CNS Pharma

Question 1

Rate limitong enzyme in catecholamine synthesis

Answer 1

Tyrosine hydroxylase

Question 2

Inhibits vesicular uptake of ACh (storage in vesicles of NT)

Answer 2

VESAMICOL inhibits vesicular uptake of ACh

Question 3

Inhibits vesicular uptake of DA/NE (storage in vesicles of NT)

Answer 3

RESERPINE inhibits vesicular uptake of DA/NE

Question 4

Prevents vesicular binding and release of ACh, leading to paralysis of muscles

Answer 4

BOTOX Prevents vesicular binding and release of ACh, leading to paralysis of muscles

Question 5

Prevents release of glycine

Answer 5

TETANUS TOXIN prevemts release of glycine

Question 6

Inhibits NE reuptake

Answer 6

DESIPRAMINE (a tricyclic antidepressant) inhibits NE reuptake

Question 7

Inhibits DA reuptake

Answer 7

COCAINE inhibits DA reuptake

Question 8

Examples of selective serotonin reuptake inhibitors (SSRI)

Answer 8

Fluoxerine

Setraline

Question 9

Example of acetylcholinesterase inhibitor

Answer 9

Pyridostigmine for myasthenia gravis