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THER 201 Therapeutics > B-lactam Antibiotics > Flashcards

B-lactam Antibiotics Flashcards

1
Q

Natural Penicillin depository preparation

A

Benzathine Penicillin

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2
Q 
Natural Penicillin oral formulation
Poor g(-) activity
A

Penicillin VK

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3
Q

Natural Penicillin spectrum of activity

g(+)

A

Natural Penicillin spectrum of activity
g(+)

SSCLECO

Streptococci
S. pneumoniae
Corynebacterium
Listeria
Enterococcus
Clostridium 
Oral anaerobes
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4
Q

Natural Penicillin spectrum of activity

g(-)

A

Natural Penicillin spectrum of activity
g(-)

Neisseria meningitidis
Haemophilus influenzae

Others:
Treponema (syphilis)
Leptospira

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5
Q

Narrow spectrum

No activity against g(-)

A

Anti-staphylococcal Penicillin

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6
Q

Anti-staphylococcal Penicillin

CONDOM

A 
Cloxacillin
Oxacillin
Nafcillin
Dicloxacillin
Oxacillin
Methicillin
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7
Q

Anti-staphylococcal Penicillin

g(+) spectrum of activity

A

Streptococci

Staphylococci

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8
Q

Resistant to CONDOM

A

MRSA: Methicillin-resistant Staphylococcus aureus

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9
Q

Anti-staphylococcal Penicillin PO (per orem)

A

Cloxacillin

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10
Q

Aminopenicillins
vs
HELPES

A

HELPES

*Haemophilus
E. coli
*Listeria
Proteus
*Enterococci
Salmonella
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11
Q

Aminopenicillin per orem

A

Amoxicillin

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12
Q

Extended Spectrum Penicillins

more g(-) coverage

A

Carbenicillin
Ticarcillin
Piperacillin

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13
Q

Highest oral bioavailability

A

Penicillin VK
Cloxacillin
Amoxicillin

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14
Q

Highest urinary recovery

A

Penicillin G > Ticarcillin = Piperacillin

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15
Q

Similar to penicillins but more stable to many bacterial beta-lactamase (thus, broader spectrum activity)

A

Cephalosporins

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16
Q

First Generation Cephalosporins

FA - IV
PHA - Pho

A

First Generation Cephalosporins

CeFAzolin - IV
CePHAlexin - PO

17
Q

Cephalosporin that is active against g(-)

A

First Generation Cephalosporins

18
Q

Exetended Spectrum Penicillin

Spectrum activity g(+)

A

SCLECO + Pneumococci

19
Q

Cephalosporins

g(-)

A

1st gen: E. coli, Klebsiella

*2nd gen: E. coli, Klebsiella, H. influenzae, Enterobacter

3rd gen: E. coli, Klebsiella, H. influenzae, Enterobacter, Salmonella, Acinetobacter, Proteus

4th gen: E. coli, Klebsiella, H. influenzae, Enterobacter, Salmonella, Acineyobacter, Proteus, Pseudomonad

*5th gen: E. coli, Klebsiella, H. influenzae, Enterobacter

20
Q

Adverse effect of CefTRIaxone

A

Biliary sludge

THER 201 Therapeutics (7 decks)

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