CNS - NAUSEA Flashcards

1
Q

When should antiemetics be given?

A
  • When the cause is known

- need to identify the cause first e.g. DKA, digoxin, epileptic overdose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is effective in nausea and vomiting that result from underlying conditions?

A

antihistamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are some examples of phenothiazines?

A
  • prochlorphenazine, perphenazine, trifluoperazine = less sedating
  • chlorphenazine = sedating
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are phenothiazines effective against?

A
  • prophylaxis and treatment of n&v caused by - neoplastic disease, radiation sickness, emesis caused by other drugs e.g. opioids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Metoclopramide:

A
  • acts directly on GI tract
  • Can only be prescribed for up to 5 days due to risk of neurological side effects
  • usual dose = 10mg TDS
  • IV dose - administered slowly over 3 minutes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Domperidone:

A
  • does not cross bbb = less central effects such as sedation
  • good to use in parkinsons for nausea caused by drugs
  • use at the lowest effective dose for the shortest period of time - max 7 days
  • CI in cardiac disease or drugs that prolong QT
  • Recommended dose in adults over 12 and over 35kg = 10mg up to TDS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ondansetron and Granisetron:

A
  • management of n&v in pts receiving cytotoxics and in postperative n&v
  • palonosetron = for high cytotoxic chemo - can also be used in combo w netupitant
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dexamethasone:

A
  • can be used in vomiting associated with cancer chemo

- can be used with metoclopramide, prochlorperazone, lorazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is appropriate to give if n&v is really bad in pregnancy?

A

antihistamine e.g. promethazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are risk factors for post operative surgery?

A
  • type of anaesthetic used
  • duration of surgery
  • females
  • non smokers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is usually given to prevent motion sickness?

A

hyoscine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly