CNS Infections Flashcards

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1
Q

What is meningism

A

Symptoms such as stiff neck, photophobia, rash and headache typically associated with meningitis

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2
Q

What Infective organisms are common for neonates

A

Group B Beta Haemolytic
E Coli
Listeria

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3
Q

Where is listeria found and who does it commonly target

A

Found in cheese

Targets Neonates, Elderly and immunocompromised

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4
Q

What is Encephalitis

A

Infected cerebral cortex w/HSV-1

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5
Q

What is meningoencephalitis

A

Infected cerebral cortex with infected meninges

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6
Q

How are CNS infections Investigated

A

CSF Analysis (Cell count, Gram stain, Protein, Glucose)
Blood Culture and PCR
Throat swab

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7
Q

What colour is bacterial CSF

A

Yellow
Raised protein
Raised WCC

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8
Q

What colour is viral CSF

A

Clear
Raised protein
Raised lymphocytes

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9
Q

What colour is TB and Fungi CSF

A

Yellow fibrous
Raised Protein
Raised lymphocytes

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10
Q

A patient with N Meningitidis presents with what haemotological disorder

A

DIC sepsis
-Purpuric rash
Diagnosis of Gonococcal Meningitis

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11
Q

Name an Optochin sensitive organism

A

S Pneumonia

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12
Q

Name an Optochin resistant Organism

A

S Viridans

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13
Q

What are the general treatments for CNS infections

A

Ceftriaxone/Ceotaxime

w/ Steroids

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14
Q

Why is H Influenzae known and fastidious

A

It is a gram negative bacteria which needs Factor 5 and 10 to grow

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15
Q

What should be given for suspected listeria

A

IV Amoxicillin

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16
Q

What two steps are taken in Close contact tracing

A

Immediate notification to Public Health England

Ciproflaxin for Close contacts

17
Q

What lobe is typically affected by Encephalitis

A

Temporal lobe

18
Q

How is Encephalitis diagnosed

A

CSF

HSV-1 PCR

19
Q

How is Encephalitis treated

A

IV Aciclovir against HSV-1