CNS BNF quiz Flashcards
Which class of drugs does cimetidine belong to?
A- H1 receptor agonist
B- H2 receptor agonist
C- H2 receptor antagonist
D- H1 receptor antagonist
C - H2 receptor antagonist
You are conducting an antidepressant medication review with Mr PL who is 79 years old. You have been seeing Mr PL who was commenced on Sertraline 50mg 1 OD a year and a half ago since the passing of his wife. Today Mr PL informs you he feels as though he does not need this medication anymore and is informing you, he is in a much better place. He has, over the last week or so started to wonder is he can come off this medication.
How long should antidepressant treatment be continued in Mr PL following remission?
At least 6 months
Miss U, 73 years old is new to the practice. You are currently conducting a meds reconciliation from her previous practice notes. From the notes, you can see that she has been stabilised on a brand of Lithium Citrate for 20 years, and her bloods from the last 3 years all show Lithium being in range. She also has her annual secondary care mental health review with the psychiatry team.
How often should Miss U come in for monitoring for her Lithium?
A- Every fortnight
B- Every month
C- 3 monthly
D- 6 monthly
C - 3 monthly once dose is stable
Mr L, 58 years old has come into the practice today to see his regular GP. Mr L has recently been experiencing pain in his back. Below is the list of medication Mr L is currently taking.
Priadel 400mg tablets
Levothyroxine 100mg tablets
Olanzapine 10mg tablets
What would be the least suitable analgesic to prescribe, considering Mr L’s medication?
A- Naproxen
B- Paracetamol
C- Codeine
D- Meptazinol
A- Naproxen
Naproxen increases concentration of lithium
TOXICITY RISK
Mr K 89 years old, has been admitted to the ward. He was admitted due to experiencing nausea and vomiting, being very confused and irritable. Some blood tests have been conducted, and the results have come back showing a reduction in sodium levels.
Which of the following medications below is likely to have caused a reduction in sodium levels?
A- Citalopram
B- Olanzapine
C- Temazepam
D- Zopiclone
A- Citalopram
SSRIs can cause hyponatraemia
Miss P, a 17-year-old girl has been referred to CAMHS to help with her ongoing persistent sadness and low mood. The specialist has decided to offer pharmacological therapy alongside the psychological therapy which Miss P is undertaking.
Which of the following is most appropriate to offer as first line drug treatment to Miss P?
A- Sertraline
B- Clozapine
C- Fluoxetine
D- Venlafaxine
C-Fluoxetine
Preferred for under 18s due to longer half life so safer profile in overdose
Which of the following antipsychotics has the lowest risk of Diabetes?
A- Haloperidol
B- Clozapine
C- Olanzapine
D- Quetiapine
A- Haloperidol
Clozapine, Quetiapine and Olanzapine increase glucose in urine = DIABETES RISK
Mr S has had Parkinson’s disease for 3 years now and is on Co-Beneldopa to help manage his symptoms. Unfortunately, today he has also been diagnosed with Dementia.
Which of the following drugs would be the most appropriate for him to be put on?
A- Donepezil
B- Galantamine
C- Rivastigmine
D- Memantine
C- RIVASTIGMINE
First line for memory loss associated in PD
Entacapone can colour your urine what colour?
A- Red/yellow
B- Orange/yellow
C-Orange/yellow
D-Red/brown
D- Red / brown
Mrs R brings in a prescription for Duloxetine. Your pre-reg student asks you what drug class this belongs to, what answer do you give?
A- SSRI
B-TCA
C-SNRI
D-MAOI’s
C- SNRI
Which of the following drugs below has both opioid agonist and antagonist properties?
A- Methadone
B- Gabapentin
C- Topiramate
D- Buprenorphine
D- Buprenorphine
How many weeks can it take for Buspirone to work?
A- Up to 1 week
B- Up to 2 weeks
C- Up to 3 weeks
D- Up to 4 weeks
B- Up to 2 weeks
Used for short term, usually after an event that causes anxiety
Mrs K Alory comes into the pharmacy to collect her monthly repeat prescription of medications. You are chatting away to her and notice that she’s not her usual self and ask if she is okay. She informs you that she has been putting on weight recently and unsure why. She is not eating any more than normal and is exercising the same amount and believes it may be down the medications.
Which of the medications below is likely to have caused Mrs K Alory’s weight gain?
A- Metformin
B- Pizotifen
C- Methylphenidate
D- Semaglutide
B- Pizotifen
Mr P 69-years-old has presented a prescription for Co-Careldopa 25/100mg TDS. He has been diagnosed with having Parkinson’s disease and has been commenced on this medication. Mr P asks you what side effects could possibly be related to this medication.
Which of the following adverse effect is NOT associated with taking Co-Careldopa?
A- Binge eating
B- Hypersexuality
C- Urine discolouration
D- Dry eyes
D- Dry eyes
Mrs P 34-years-old, has been experiencing severe back pain, which has not responded to paracetamol, and topical analgesia. Mrs P also suffers from hypothyroidism and epilepsy.
Which of the following analgesics would be LEAST suitable for Mrs P?
A- Naproxen
B- Tramadol
C- Aspirin
D- Ibuprofen
B- Tramadol
Reduces seizure threshold
Not suitable in epileptics
Which of the following opioids below is likely to exert it affect by being a mu-receptor agonist, and also enhancing serotonergic and adrenergic pathways?
A- Morphine
B- Tramadol
C- Oxycodone
D- Buprenorphine
B- Tramadol
Which of the following drugs below is used to treat moderate to severe dementia in Alzheimer’s disease?
A- Donepezil
B- Memantine
C- Galantamine
D- Rivastigmine
A- Memantine
Donepezil, Rivastigmine and Galantamine = mild-moderate dementia
The MHRA have released guidance relating to the prolonged use of a medication. It reinforces the fact that, prolonged use of this medication can cause serious neurological adverse effects, and that this medication should not be used for more than 5 days.
Which medication is this guidance most likely to be related to?
A- Metoclopramide
B- Tramadol
C- Oxycodone
D- Domperidone
A- Metoclopramide
Only for short term use
Which one of the drugs below can be used for the treatment of nocturnal enuresis in children?
A-Citalopram
B-Sertraline
C-Imipramine
D-Duloxetine
C- Imipramine
A 55-year-old man has recently been diagnosed with stage 2 hypertension.
Other medical conditions include T2DM and Depression.
NKDA
His current medication includes:
Atorvastatin 20mg ON Metformin 1g BD
Sertraline 50mg OD
Which antihypertensive should this patient be started on first line?
A- Amlodipine
B- Doxazosin
C- Indapamide
D- Ramipril
E- Bisoprolol
D- Ramipril
ACE inhibitors are first line for HTN in diabetic patients
If he didn’t have T2DM it would be a CCB as he is 55+
