CNS basics

Question 1

GABA receptor types

Answer 1

GABA-A is a fast Cl channel

GABA-B is slow GPCR

Question 2

GABA roles

Answer 2

Sleep
Anxiety
Epilepsy
Muscle relaxation
Disinhibition via inhibition of GABA

Question 3

ACh receptor types

Answer 3

Excites through ionotropic nicotinic receptors

Excites and inhibits through metabotropic muscarinic

Question 4

Monoamine receptor types

Answer 4

NA, dopamine, 5HT receptors all slow GPCR except 5HT3 - fast ionotropic

Question 5

Peptides and inhibit/excite

Answer 5

Substance P excites

Opioids inhibit