CNS-Alcohol

Question 1

what are the acute effects of ethanol on the CNS system?

Answer 1

dose-dependent CNS depression (ˇ membrane excitability + ^GABAa & ˇ NMDA acivation)
diuresis
ˇ myocardial contractility
ˇ anxiety, slurred speech, impaired judgement

toxic doses: CNS and respiratory depression.

Question 2

what are the chronic effects of ethanol on the CNS system?

Answer 2

fatty liver->hepatitis-> cirrhosis ->liver failure
pancreatits & gastritis
malnutrition

Question 3

how is ethanol eliminated from the human body?

Answer 3

> 90% is metabolized by the liver (oxidation)

Question 4

what is methanol, and how is it metabolized?

Answer 4

wood alchohol

methanol metabolism -> formic acid -> blindness

Question 5

how do you treat methanol consumption?

Answer 5

ethanol. it has a higher affinity for alcohol dehydrogenase therefore it slows methanol metabolism to formic acid