CNS

Question 1

Dose of adrenaline (epinephrine) in case of anaphylaxis

Answer 1

0.3 - 0.5 ml 1:1000 solution - intramuscular

Acts within minutes

If initial response is inadequate, repeat at 5-10 minute intervals

Question 2

Sites of involvement in angioedema

Answer 2

Face
Extremities
Genitalia

Question 3

HAM

Answer 3

HTLV-1 asso. myelopathy

Tropical spastic paraplegia

Question 4

Essential amino acids

Answer 4

Valine 
Lysine 
Leucine, isoleucine
Phenylalanine
Tryptophan
Methionine
Histidine
Threonine

Question 5

Pickwickian syndrome

Answer 5

Obesity hypoventilation syndrome

• complication of obesity occurring as a result of restricted ventilation

Question 6

Zinc containing enzymes

Answer 6

CA - carbonic anhydrase

ALD - Alcohol dehydrogenase

ALP

Question 7

First rank symptoms of acute schizophrenia

Answer 7

A - Auditory hallucinations (Écho de la pensée)

B - Broadcasting, insertion/withdrawal of thoughts

C - Controlled feelings, impulses or acts (passivity experiences/phenomena)

D - Delusional perception

Question 8

Metabolic complications of eating disorders

Answer 8

Uremia

Renal calculi

Osteoporosis

Question 9

Cardiac abnormalities in eating disorders

Answer 9

ECG - T wave inversion, ST depression, prolonged QT interval

Arrhythmias - profound sinus bradycardia, ventricular tachycardia

Question 10

Parasitic infections involving CNS

Answer 10

Malaria 
Chagas' disease
African sleeping sickness
Toxoplasmosis 
Loiasis
Schistosomiasis 
Strongyloidiasis 
Cysticercosis
Diphyllobothrium latum infection

Question 11

Fungal infections involving CNS

Answer 11

Candidiasis

Cryptococcosis

Coccidiodomycosis

Question 12

PUO

Answer 12

Temperature persistently > 38 C
> 3 weeks without diagnosis

Despite initial investigation during

• 3 days of IP care
• more than 2 OP visits

Question 13

Types of PUO

Answer 13

HIV-1 related

Immunodeficient

Nosocomial

Question 14

MC presenting feature of Toxoplasmosis

Answer 14

Painless lymphadenopathy - local or generalised

MC involves - cervical LN

Question 15

Long term sequelae of congenital toxoplasmosis

Answer 15

Retinochoroiditis

Microcephaly

Hydrocephalus

Question 16

Serological test in toxoplasmosis

Answer 16

Sabin Feldman dye test (Indirect fluorescent antibody test)

Detects IgG antibody

Recent infection - 4x increase

Question 17

Blood counts in Kala azar

Answer 17

Pancytopenia

Granulocytopenia

Monocytosis

Question 18

CNS manifestation of loiasis

Answer 18

Encephalitis - in heavy infections especially after treating (due to heavy microfilaremia)

Question 19

CNS involvement in vit B12 deficiency

Answer 19

Peripheral nerves

Spinal cord - SCD

Cerebrum - dementia, optic atrophy

Autonomic neuropathy

Question 20

Peripheral nerves involvement in vit B12 deficiency

Answer 20

Glove & stocking paraesthesia

Loss of ankle reflexes

Question 21

Alice in wonderland sydrome - Clinical features

Answer 21

Hallucinations

Sense of time - lost

Altered perception of body parts size & shape

Altered perception of external objects size & shape

Question 22

Causes of sterile meningitis

Answer 22

Malignancy

• Breast, Bronchus
• Leukemia, Lymphoma

Inflammatory diseases

• Sarcoidosis
• SLE
• Behçet’s disease