CNS Flashcards

1
Q

Dose of adrenaline (epinephrine) in case of anaphylaxis

A

0.3 - 0.5 ml 1:1000 solution - intramuscular

Acts within minutes

If initial response is inadequate, repeat at 5-10 minute intervals

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2
Q

Sites of involvement in angioedema

A

Face
Extremities
Genitalia

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3
Q

HAM

A

HTLV-1 asso. myelopathy

Tropical spastic paraplegia

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4
Q

Essential amino acids

A
Valine 
Lysine 
Leucine, isoleucine
Phenylalanine
Tryptophan
Methionine
Histidine
Threonine
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5
Q

Pickwickian syndrome

A

Obesity hypoventilation syndrome

  • complication of obesity occurring as a result of restricted ventilation
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6
Q

Zinc containing enzymes

A

CA - carbonic anhydrase

ALD - Alcohol dehydrogenase

ALP

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7
Q

First rank symptoms of acute schizophrenia

A

A - Auditory hallucinations (Écho de la pensée)

B - Broadcasting, insertion/withdrawal of thoughts

C - Controlled feelings, impulses or acts (passivity experiences/phenomena)

D - Delusional perception

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8
Q

Metabolic complications of eating disorders

A

Uremia

Renal calculi

Osteoporosis

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9
Q

Cardiac abnormalities in eating disorders

A

ECG - T wave inversion, ST depression, prolonged QT interval

Arrhythmias - profound sinus bradycardia, ventricular tachycardia

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10
Q

Parasitic infections involving CNS

A
Malaria 
Chagas' disease
African sleeping sickness
Toxoplasmosis 
Loiasis
Schistosomiasis 
Strongyloidiasis 
Cysticercosis
Diphyllobothrium latum infection
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11
Q

Fungal infections involving CNS

A

Candidiasis

Cryptococcosis

Coccidiodomycosis

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12
Q

PUO

A

Temperature persistently > 38 C
> 3 weeks without diagnosis

Despite initial investigation during

  • 3 days of IP care
  • more than 2 OP visits
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13
Q

Types of PUO

A

HIV-1 related

Immunodeficient

Nosocomial

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14
Q

MC presenting feature of Toxoplasmosis

A

Painless lymphadenopathy - local or generalised

MC involves - cervical LN

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15
Q

Long term sequelae of congenital toxoplasmosis

A

Retinochoroiditis

Microcephaly

Hydrocephalus

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16
Q

Serological test in toxoplasmosis

A

Sabin Feldman dye test (Indirect fluorescent antibody test)

Detects IgG antibody

Recent infection - 4x increase

17
Q

Blood counts in Kala azar

A

Pancytopenia

Granulocytopenia

Monocytosis

18
Q

CNS manifestation of loiasis

A

Encephalitis - in heavy infections especially after treating (due to heavy microfilaremia)

19
Q

CNS involvement in vit B12 deficiency

A

Peripheral nerves

Spinal cord - SCD

Cerebrum - dementia, optic atrophy

Autonomic neuropathy

20
Q

Peripheral nerves involvement in vit B12 deficiency

A

Glove & stocking paraesthesia

Loss of ankle reflexes

21
Q

Alice in wonderland sydrome - Clinical features

A

Hallucinations

Sense of time - lost

Altered perception of body parts size & shape

Altered perception of external objects size & shape

22
Q

Causes of sterile meningitis

A

Malignancy

  • Breast, Bronchus
  • Leukemia, Lymphoma

Inflammatory diseases

  • Sarcoidosis
  • SLE
  • Behçet’s disease