CNS Flashcards
what is the origin of a psychiatric disorder?
psychogenic origin without evidence of structural or biochemical abnormaility
what does the -schizo in schizophrenia mean?
loss of perception of reality
what are examples of negative effects caused from treatment of psychiatric disorders?
flat affect and apathy
what is the name of the disorder when patients exhibit alternating periods of depression and excitation (mania, elation)
bipolar depression, also known as manic-depressive disorder
the amount of any drug prescribed at one time should not exceed what amount when the drug is for a depressed or suicidal patient?
the amount required for a lethal dose, usually a 1-week supply
how do the side effects of the second-generation antipsychotics compare with those of the first generation?
less side effects with 2nd generation
what is the mechanism of action of first generation antipsychotic agents?
dopamine antagonist
how do first-generation antipsychotics work on both the positive and negative effects of psychosis?
active against the positive effects of psychosis but have little effect on the negative effects
first-generation antipsychotics would have little effect on which symptom of psychosis?
flat affect
first generation antipsychotic therapy must often be combined with what other drugs to control excessive extrapyramidal stimulation?
anticholinergic drugs such as benztropine
second generation antipsychotics are primarily antagonists at what receptor types?
Norepinephrine
Dopamine
Serotonin
extrapyramidal effects or movement disorders can occur with what drugs?
all first-generation antipsychotics
what are involuntary, repetitive body movements involving the tongue, lips, face, and jaw called?
tardive dyskinesia
what are involuntary, repetitive body movements involving the tongue, lips, face, and jaw called?
tardive dyskinesia
what are extrapyramidal effects exacerbated by?
drug withdrawal
