CN III Flashcards

1
Q

Function of CN V

A
  • General sensation
  • General propriocepation from extraocular muscles, TMJ, muscles of mastication etc
  • Skeletal motor to muscles of mastication and some others
  • CARRIES parasympathetic “hitch hikers” of other cranial neres and sympathetic fibers from the internal carotid plexus in its own branches.
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2
Q

What are the parasympathetic fibers that CN V carries

A
  • OCULOMOTOR: parasympathetic fibers leave CILIARY GANGLION via opthalamic division (V1) to terminate in SPHINCTER PUPILLAE and CILIARY MUSCLES
  • FACIAL: Parasympathetic fibers leave the PTERYGOPALATINE GANGLION via the maxillary division (V2) to terminate int he LACRIMAL, NASAL and PALATINE GLANDS
  • FACIAL: Parasympathetic fibers leave SUBMANDIBULAR GANGLION via the mandibular divison (V3) to terminate in the PAROTID GLAND
  • GLOSSOPHARYNGEAL: parasympathetic fibers leave OTIC GANGLION via mandibular division (V3) to terminate in PAROTID GLAND
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3
Q

Describe the sympathetic “hitch hikers” that the trigeminal nerve carries

A
  • Sympathetic hitch hikers from the internal carotid plexus are carried by OPTHALAMIC DIVISION (V1) to the dilator pupillae muscle
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4
Q

What are the divisons of the Trigeminal nerve and are they motor or sensory

A
  • Opthalamic = sensory
  • Maxillary = sensory
  • Mandibular = sensory and motor
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5
Q

What neruons are found in Trigeminal ganglion (Gasserian ganglion)

A
  • Is a sensory ganglion
  • contains PSEUDOUNIPOLAR NEURONS
  • no synapses
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6
Q

Define Mesencephalic nucleus of the trigeminal

A
  • Sensory nuclei
  • located in midbrain
  • Function = general proprioception from muscles innervated by trigeminal nerve and periodental ligament (PDL)
  • -> muscles of mastication and PDL contain nerve receptors that convey info to the brain about position of the jaw
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7
Q

Define Principal (main, Chief) sensory nucleus of tigeminal

A
  • Sensory nuclei
  • Location = midpons
  • Function = discriminatory (fine, detailed) touch and pressure sensation from orofacial structures, GP from extraocular muscles and TMJ

–> sensory input is relayed to principal nucleus by central processes of sensory neurons located in V ganglion

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8
Q

define the spinal nucleus of the trigeminal

A
  • Sensory nuclei
  • Located = pons, medulla, extends to spinal cord levels C1-C2(3)

–> sits on top of substantia gelatinosa of the spinal cord

  • FUNCTION = nociceptive and thermal sensation and some tactile sense from orofacial structures (resembles substantia gelatinosa structuraly and functionaly)

** ONLY cranial nerve that has PAIN NUCLEUS**

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9
Q

Define Motor nucleus of trigeminal

A
  • Motor nucleus
  • Location = midpons
  • Function = contains cell bodies of motor neurons whose axons gather to from motor root of trigeminal nerve

–> innervate muscles of mastication and a few others

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10
Q

define the spinal tract of trigeminal

A
  • Origin = Pons, near sensory root of V
  • Course = descends in pons, through medulla to C1 or C2
  • Termination = spinal nucleus of trigeminal (pons, medulla, C1-C2)
  • Function = Pain, temperature, some tactile sense

**merges with lissauers tract at upper cervical levels**

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11
Q

Define ventral trigeminal lemniscus (ventral trigeminothalamic tract)

A
  • origin = spinal nucleus of V
  • Course = ascends to the thalamus
  • Termination = VPM nucleus of thalamus
  • Function = pain, temeprature, tactile sensation

** similar to spinothalamic tract of anteriolateral system **

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12
Q

Define dorsal trigeminal lemniscus (dorsal trigemnothalamic tract)

A
  • Origin = main sensory nucleus of V
  • Course = ascends to the thalamus
  • Termiantion = VPM nucleus of thalamus
  • Function = discriminative (fine, detailed) touch, proprioception

** similar to medial lemniscus **

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13
Q

Define tigeminoreticular fibers

A
  • Origin = main sensory nucleus/spinal nucleus of V
  • Course = project to nearby brainstem reticular formation, BILATERALLY
  • Termination = reticular formation
  • Function = Arousal, produced by stroking or slapping the face, or “smelling salts” (containing ammonia)

** similar to/counterpatrs of spinoreticular tract **

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14
Q

Describe the pathways of the trigeminal nerve: Discriminatory touch and pressure sensation of orofacial region

A
  • 1st order neuron cell bodies found in TRIGEMINAL GANGLION –> terminate in MAIN SENSORY NUCLEUS OF V
  • 2nd order neurons are located in MAIN SENSORY NUCLEUS and their axons join the DORSAL TRIGEMINAL LEMNISCUS to ascend to the VPM nucleus of thalamus
  • 3rd order neurons in VPM project to the POSTCENTRAL GYRUS (representing orofacial region)
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15
Q

describe the pathway of the rigeminal nerve: pain and temperature sensation

A
  • 1st order neruon: cell bodies found in trigeminal ganglion and DESCEND in the spinal tract of V to terminate in SPINAL NUCLEUS OF V
  • 2nd order neurons located in SPINAL NUCLEUS OF V join VENRAL TRIGEMINAL LEMNISCUS to ASCEND TO VPM
  • 3rd order neurons in VPM project to POSTCENTRAL GYRUS as well as ANTERIOR CINGULATE and ANTERIOR INSULAR CORTICES (emotional component of pain)
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16
Q

Describe the pathway of the trigeminal nerve: Motor pathway

A
  • Lower motor neuron cell bodies found in MOTOR NUCLEUS of V
  • Axons exit brianstem at MIDPONTINE LEVEL as motor root of V
  • Axons join the MANDIBULAR DIVISION of the trigeminal to districute to ALL MUSCLES INNERVATED by trigeminal
17
Q

describe the pathway of trigeminal nerve: general proprioception Pathway

A
  • 1st order neuron located in MESENCEPHALIC NUCLEUS (contains PSEUDOUNIPOLAR NEURONS) distribute their peripheral processes with braches of trigeminal nerve
  • Central processes terminal in the MAIN SENSORY NUCLEUS OF V (for jaw sensation) and motor nucleus of V (for reflex movement of jaw)
18
Q

Describe the role of the trigeminal nerve in the corneal blinke reflex

A
  • ophthalamic division of trigeminal nerve forms the AFFERENT (sensory) limb of the corneal blink reflex arc
  • facial nerve forms the EFFERENT (motor) limb of the reflex arc
19
Q

What will damage to opthalmic division result in?

A
  • Reduce sensation over V1 zone
  • Inhibit corneal blink reflex
20
Q

damage to the maxillary division will result in?

A
  • reduce or inhibit sensation over the V2 zone
21
Q

damage to the mandibular division will result in?

A
  • reduce or inhibit sensation over V3 zone
  • may cause paralysis of muscles of mastication resulting in jaw or DEVIATE TO THE SIDE OF THE LESION
22
Q

describe the characteristics of Trigeminal neuralgia

A
  • characterized by sharp, excruciating intermittent pain on ONE SIDE OF FACE brought on by touching of the affected side of face, brushign teeth or moving mouth
  • spontaneous onset and each attack lasts for few seconds but individual feels fine between attacks

–> pain is so bad that patients contemplate suicide

23
Q

what is the cause of trigeminal neuralgia

A

1) demyelination of trigeminal nerve (resulting from demyelinating disease) as it enters the pons of the brainstem
2) vascular structures (SUPERIOR CEREBELLAR ARTERY) or loops may develop next to or surround (compressing) one of the division of trigeminal nerve (opthalmic or maxillary)

–> compression results in demyelination

**demyelination results in ephaptic transmission of nerve impulses (short circutiing or cross talk between adjacent fibers) **

24
Q

result of a lesion to SPINAL V TRACT and or SPINAL V NUCLEUS between midpon and C2

A
  • Loss of pain and temeprature sensation
  • diminution of tactile sense

** from IPSILATERAL OROFACIAL REGION and GSA territory of VII, IX and X **

25
Q

result of a lesion to ventral V lemniscus

A
  • loss of pain and temperature sensation
  • Diminution of tactile sense

**from CONTRALATERAL orofacial region and GSA territory of VII, IX, and X **

26
Q

Result of a lesion to dorsal V lemniscus anywhere between the midpons to the thalamus

A
  • diminution of tactile sensation from the IPSILATERAL OROFACIAL REGION

–> not total loss of tactile sensation because some fibers from main nucleus ascend to the venral V lemniscus