CN Course and Distribution Flashcards
III
Oculomotor
- Anterior midbrain
- Middle cranial fossa
- Lateral wall of cavernous sinus
- Divides into superior (LPS and SR) and inferior (MR, IR, IO)
- Passes through superior orbital fissure
- Eye muscles
Which oculomotor branch has somatic motor and parasympathetic nerves passing through?
Inferior
Superior
- GSE - LPS and SR
Inferior
- GSE - MR, IR,IO
- GVE - ciliary and sphincter pupillae
How does parasympathetic innervation of III get to its destination?
Hitch hikes on short ciliary nerves (of V1)
Sympathetic innervation of intrinsic eye muscles
Pre-gang neurons to superior cerivical ganglia
Post-gang neurons to long and short ciliary nn.
- Wrap around IC artery
- IC plexus
Innervates
- Dilator pupillae
- Ciliary mm.
- Superior tarsal m.
- SM
- Attached to LPS and lid
- Opens lid up ALL THE WAY
CN III lesions
Diplopia
Lateral strabismus
Mydriasis
Dry eye
Ptosis
VII
- Two roots from pons near PMJ
- Laterally in posterior cranial fossa with vestibulocochlear n.
- Enter IAM
- Pass through facial canal, branch into GP and CT
- Remaining VII is facial n. proper and continues down through stylomastoid foramen
- Posterior auricular n., Posterior digastric n., Stylomastoid branch off
- Pass THROUGH parotid to form plexus
- TZBMC
CN IX lesions
Supranuclear (in brain) = contralateral paralysis
- Tongue goes to side opposite of injury
Peripheral (after leaving brainstem) = ipsilateral paralsys
- Tongue goes to same side of injury/lesion
- “Lick your wounds”
Parasympathetic innervation of lacrimal gland
Pre-gang
- Super sal nuc.
- GP of VII
- Joins with DP (symp) = vidian n.
Post-gang
- Pterygopalatine gang
- Hitch hikes on zygomatic n. of V1
- Hitch hikes on lacrimal gland of V2 to innervate lac gland (what actually stimulates tears) via lac n. of V1
Parasympathetic: chorda tympani
Joins V3 on the way to sublingual and submandibular glands
Goes through submandibular ganglion
Posterior auricular n. innervates what muscle?
Auricularis posterior and occipitalis
Temporal n. innverates what muscle?
Motor - auricularis anterior/superior, frontalis, orbicularis oculi, corrugator supercilii, procerus
Zygomatic (malar) n. innverates what muscle?
Motor - orbicularis oculi and zygomaticus
Buccal (infraorbital) n. innervatess what muscle?
Motor - buccinator, orbicularis oris
Mandibular (maginal) n. innervates what muscle?
Motor - depressor labii inferioris, depressor anguli oris, mentalis
Cervical n. innervates what muscle?
Motor - depressor anguli oris and platysma
CN VII lesions
Bell’s Palsy - unilateral face paralysis from damage to SVE of VII
Temporary from dental procedures
- Inferior alveolar nerve block into parotid bed
- Improves when anesthetic wears off
Affected at stylomastoid foramen
CN IX
- Anterior medulla
- Passes laterally in posterior cranial fossa
- Jugular foramen
- Descends through upper part of neck to back of tongue
Tympanic n.
Branch of IX
- Enters middle ear cavity
- Sensory and pre-gang para fibers
- Forms part of tympanic plexus
Tympanic plexus
IX br
Sensory and sympa to middle ear cavity, pharyngotympanic tube, mastoid air cells
Lesser petrosal
IX br
- Travels through foramen ovale
- Fibers synapse in otic gang
- Travel to parotid
- Hitch hiking on V3, auriculotemporal n.
Parasympathetic innervation of parotid
Pre-gang neuron
- Inferior sal. nuc
- IX exits jugular foramen
- Tympanic n. of IX joins tympanic plexus = lesser petrosal n.
- Lesser petrosal exits foramen ovale
Post-gang neuron
- Otic gang
- Hitch hikes on auriculotemporal n. of V3
X
- Anterior medulla
- Laterally pass through posterior cranial fossa
- Pass through jugular
- Descends through neck along carotid arteries and internal jugular vein in carotid sheath
- Through mediastinum
- Pierces diaphragm with esophagus
- Terminal br in abdomen
- Most extensive distribution
X br
Pharyngeal
Superior laryngeal
- Internal laryngeal
- External laryngeal
Recurrent laryngeal
Pharyngeal plexus components
IX - glossopharyngeal n.
X - vagus n.
XI - accessory n., cranial part
X lesions
Soft palate
- Paralyzes larynx muscles ipsilateral of lesion
- Uvula deviates AWAY from lesion
Larynx
- Paralyze larynx mm. ipsilateral of lesion
- Unilateral = hoarseness
- Bilateral = dyspnea
Which cranial nn. travel through cavernous sinus?
III
IV
V1, V2
VI
6 major br. of cervical plexus? What CN are they associated with?
- Great auricularis n.
- Supraclavicular n.
- Phrenic n.
- Lesser occipital n.
- Ansa cervicalis
- Transverse cervical n.
XII
What are the major cutaneous br?
- Lesser occipital n.
- C2
- Great auricular n.
- C2, C3
- Transverse cervical n.
- C2, C3
- Supraclavicular n.
- C3, C4
What is Erb’s pt?
Where 4 br. of cervical plexus (cutaneous br) emerge from behind SCM
LGTS
Surgical landmark
Phrenic n.
C3, C4, C5 keep the diaphragm alive
Runs along anterior scalene, deep to carotid sheath
Mixed n.
Ansa cervicalis
Motor
Loop of n. fibers
- Superior - C1
- Inferior - C2, C3
Travel WITH CN XII
Innervates 3 of 4 infrahyoid mm.
- Omohyoid
- Sternohyoid
- Sternothyroid
I
- Olfactory nn.
- Pass through cribiform plate
- Olfactory bulb
- Olfactory tract
- Olfactory area of cerebral cortex (temporal lobe)
I lesions
Torn dura mater near cribiform plate = leaking CSF, “runny nose” after trauma
Torn olfacotry neurons
II
- Rods and cones to ganglion cells o retina
- Passes through optic canal
- Optic chiasm
- Optic tract (medial fibers switch, lateral fibers stay on same side)
- Lateral geniculate body (thalamus)
- Visual cortex of cerebrum (occipital lobe)
II lesions
Optic n. - complete blindness
Optic chiasm - bitemporal hemianopsia
Optic tract - homonymous hemianopsia
VII
- Two sets of sensory fibers = vestibular and cochlear
- Leave anterior surface pons (near PMJ)
- Cross posterior cranial fossa
- IAM with facial n.
VIII lesions
Acoustic neuroma
- Benign Schwann cell tumor
- Hearing loss and gait ataxia
- Can block CSF drainage of 4th ventricle = hydrocephaly
- Vomiting, loss of consciousness, death
IV
- Most slender n.
- Posterior surface of midbrain
- Middle cranial fossa
- Lateral cavernous sinus
- Superior orbital fissure
- Superior oblique
IV lesions
Diplopia
Eye is adducted and elevated (in and up)
VI
- Anterior surface of pons, PMJ
- Passes forward with IC artery through cavernous sinus
- Enters orbit through superior orbital fissure
- Lateral rectus
VI lesions
Diplopia
Medial strabismus
XI
- Cranial root: anterior surface of medulla
- Runs laterally in posterior cranial fossa and joins spiral root
- Spinal root: anterior gray horn of upper 5 segments of spinal cord
- Ascends along spinal cord
- Enters skull through foramen magnum
- Turns laterally to join cranial root
- Roots unite, leave skull via jugular foramen, roots separate
- Cranial joins vagus (pharyngeal plexus)
- Spinal joins SCM and traps
XI lesions
Partial paralysis of traps
- Drooping of shoulder on affected side
- Also innervated by C3-C5
Complete flaccid paralysis of SCM
-
Torticollis (wry neck)
- Unilateral injury, cannot turn neck to opposite side
- Bilateral, cannot hold head up
- Only innervated by XI
XII
- Anterior surface of medulla
- Rootlets join together to form XII
- Travel through hypoglossal canal
- Enter root of tongue superior to hyoid bone and lateral to hyoglossus
XII lesions
Supranuc (brain) - contralateral paralysis
Peripheral (after brainstem) - ipsilateral paralysis if lesion is on XII
Trigeminal sensory nuc (V, VII, IX, X): mesencephalic
Mesencephalic
- Midbrain
- Located at CN V entry
- Proprioreceptive input from joints, muscles of mastication, teeth, periodontium
- Sensory limb of jaw jerk reflex, force of bite, projects to motor nucleus of V
Trigeminal sensory nuc (V, VII, IX, X): Chief
Chief - main, pontine, primary, principle TSN
- Pons
- Lateral to motor nuc
- 2 pt discrimination or touch and pressure sensations from face, scalp, oral cavity, nasal cavity, dura
Trigeminal sensory nuc (V, VII, IX, X): Spinal
Spinal TSN (descending)
- Spinal cord to pons
- Continuation of chief TSN
- Pain and T sensations from face
V
Largest CN
- Anterior pons
- Small motor root and large sensory root
- Posterior cranial fossa
- Apex of petrous part of temporal bone in middle cranial fossa
- Sensory root forms trigeminal gang
- V1, V2, V3 branch from gang
- V1 - only S
- Cavernous sinus
- Superior orb fiss
- V2 - only S
- Cavernous sinus
- F. rotundum
- V3 - both S and M
- F. ovale
- V1 - only S
What does V1 branch off into?
- Nasociliary n.
- Posterior ethmoid n.
- Anterior ethmoid n.
- External nasal n.
- Infratrochlear
- Long ciliary n.
- Short ciliary n (via ciliary gang)
- Frontal n.
- Supraorbial n.
- Supratrochlear n.
- Lacrimal n.
Parasympathetic innervation of lacrimal gland
Pre-gang
- Super sal. nuc
- GP n. of VII
- Joins with DP (symp) to form vidian n. (nerve of pterygoid canal)
Post-gang
- Pterygopalatine gang
- Hitch hikes on V2 zygomatic n.
- Communicating br
- Hitchhikes on V1 lacrimal n.
What does V2 branch off into?
- Zygomatic n.
- (Comm to lacrimal n.)
- Zygomaticotemporal n.
- Zygomaticofacial n.
- Infraorbital n.
- (Pterygopalatine ganglion)
- Lesser (posterior) palatine n.
- Greater (anterior) palatine n.
- Nasopalatine
- PSA n.
- MSA n.
- ASA n.
- Palpebral n.
- Nasal n.
- Superior labial n.
- (Pterygopalatine ganglion)
What does V3 branch off into?
- Meningeal
- Auriculotemporal n.
- Massteric
- TT
- TVP
- Medial pterygoid
- Lateral pterygoid
- Buccal
- Deep temporal nn. - ant. and post.
- Lingual
- (Submandibular gang)
- Inferior alvolar n.
- Incisive n.
- Mental n.
- Mylohyoid
Trigeminal neuralgia
AKA tic douloureux
- Pain in V2, V3, rarely V1
- 1-2 min
- Initiatied by stimulus
- 5th-6th decades
- Usually unilateral
- Bilateral = MS
- Unknown cause
- Tx
- Anticonvulsants
- Neurosurgery
Horner’s
PAM is Horny - V
Interruption of sympa nerve supply
Causes
- Stroke
- Neck trauma
- Carotid artery injury
- Pancoast tumors
PAM - signs/symptoms
- Ptosis
- Anhidrosis
- Miosis - dilator pup. m. paralyzed
Corneal reflex
V
AKA blink reflex to protect eye
Stimulated by cornea - light, touching it
Sensory - nasociliary V1
Motor - Temporal and zygomatic branches of VII
Cough reflex
Cough receptors in resp tract - mechanical and chemical stimuli
Sensory
- X (internal laryngeal n.)
Motor
- X (recurrent laryngeal n.)
- Phrenic n.
- Intercostal m.
Gag reflex
AKA pharyngeal reflex
Contraction of back of throat stimulated by touching back of tongue, uvula, tonsils
Sensory
- Primarily IX
- Touching soft palate, V
Motor
- X
Pupillary light reflex
Miosis - constriction
Mydriasis - dilation
Sensory - II
Motor - III (symp and para)
Lens accommodation
Sensory - II
Motor - III (para)
Baroreceptor reflex
Carotid sinus and arch
Sensory
- Carotid sinus, IX
- Aortic arch, X
Motor
- Symp and para
Jawjerk reflex
AKA masseter reflex
Stretch reflex - Testing V
Mandible is tapped at a downward anglle below lips with mouth slightly open - masseter should jerk upwards
Sensory - V3
Motor - V3