CM: Inflammatory Dermatoses Flashcards
normal epidermis
infiltrate around blood vessels in superficial plexus
blood vessels dilated
superficial perivascular dermatitis w/o epidermal change
What is the clinical presentation of superficial perivascular dermatitis w/o epidermal change?
erythematous macules and patches, papules and plaques
normal epidermis –> smooth skin surface
What kinds of skin diseases commonly show a superficial perivascular dermatitis w/o epidermal change pattern?
viral exanthems
drug eruptions of morbilliform type (7-14 days after)
thickened stratum corneum = parakeratosis
alteration of dermoepidermal jxn by infiltrate
superficial perivascular dermatitis w interface change
What are the two types of superficial perivascular dermatitis w interface change?
vacuolar subtype - interface altered by vacuolated basal cells as result of inflammation
lichenoid subtype - lichen planus like, band of lymphocytes obscures interface
What is the clinical presentation of superficial perivascular dermatitis w interface change?
erythema, violaceous
papules and plaques, scale
What skin diseases commonly show superficial perivascular inflammation w interface change?
EM, dermatomyositis, lichen planus, mycosis fungoides, cutaneous t cell lymphoma
spongiosis
serum and inflammatory cells in stratum corneum
acanthosis and parakeratosis
superficial perivascular infiltrate
superficial perivascular dermatitis w spongiosis
What is the clinical presentation of superficial perivascular dermatitis w spongiosis?
erythema, papules and plaques, crust
Which skin diseases present w superficial perivascular dermatitis w spongiosis?
allergic contact dermatitis
nummular dermatitis
tinea inf
superficial perivascular infiltrate
epidermal hyperplasia due to elongation of thinned rete ridges
diminished granular layer and parakeratosis
thin epidermis above widened capillaries
neutrophils in stratum corneum or spinous layer
superficial perivascular dermatitis w psoriasiform hyperplasia
What is the clinical presentation of superficial perivascular dermatitis w psoriasiform hyperplasia?
erythema, papules and plaques, sharp circumscription of lesions, (silver) scale
What are skin diseases that show superficial perivascular dermatitis w psoriasiform hyperplasia?
psoriasis
lichen simplex chronicus
inflammatory cells in superficial and deep vascular plexuses in dermis
variable changes in epidermis
superficial and deep perivascular dermatitis
What is the clinical presentation of superficial and deep perivascular dermatitis?
erythema, papules and plaques, indurated due to deeper inflammation
What are skin diseases that present w superficial and deep perivascular dermatitis?
lupus and dermatomyositis (interface change) secondary syph (psoriasiform + lichenoid changes) arthropod bite rxn (maybe spongiosis)
perivascular aggregates of inflammatory cells around superficial and deep vascular plexi
extensive coalescence of nodular aggregates to form sheets
possible granulomas
nodular and diffuse dermatitis
What is the clinical correlation of nodular and diffuse dermatitis?
reddish-brown granulomatous infiltrates by exam
yellow-brown infiltrates on diascopy
erythematous non-granulomatous infiltrates
papules, nodules, plaques