CloudySwelling And Hydropic Degeneration

Question 1

Cloudy swelling? (2 points)

Answer 1

1-Mildest, commonest and reversible cell injury
2-characterized by cellular
swelling and cytoplasmic granularity.

Question 2

Organs affected by cloudy swelling

Answer 2

Parenchymatous organs as ((heart , kidney,liver))

Question 3

Gross picture: The affected organs

Answer 3

SERP
1-softer , enlarged, rounded borders ,pale
2- cut surface bulge outwards with tense capsule

Question 4

The pathogenesis

Answer 4

injurious agent such as hypoxia__ Mitochondrial damage__ loss of
ATP formation__ Failure of the active cell membrane transport__ Na enters the cell ___while Potassium out of the cell.___ Excessive intracellular sodium is followed
by accumulation of water inside the cell.

Question 5

Microscopic picture (3 points)

Answer 5

1-The cells are swollen by entry of water
2-granular cytoplasm (due to damaged mitochondria).
3-The nucleus is normal.

Question 6

The fate (2 options)

Answer 6

1-It is reversible process after removal of the injurious agent.
OR
2-it may proceeds
to hydropic degeneration. NiXo

Question 7

What is the difference between cloudy swelling and Hydrobic degeneration?

Answer 7

Both are reversible cell injury, but hydropic degeneration has extra amount of fluid inside the cell

Question 8

How can the fluid accumulated inside the cell in hydrobic degeneration?

Answer 8

1-small multiple vacuoles
2-Single large vacuole replacing the site place and displacing normal nucleus

Question 9

Definition of hydropic de generation

Answer 9

The last 2 cards

Question 10

Example of hydropic degeneration

Answer 10

1-epidermis in burns
2-renal tubules in diarrhea
3- liver cell in viral hepatitis
4- pancreatic islets of langerhans in diabetes mellitus