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ASDOH Hematology > Clotting factors > Flashcards

Clotting factors Flashcards

1
Q

What are the clotting factors that are found outside the liver?

A

III (3)
IV (4)
XII (12)
XIII (13)

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2
Q

Clotting factor 1 Name and Origin…

A

Fibrinogen, Liver

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3
Q

Clotting factor 2 Name and Origin…

A

Prothrombin, Liver

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4
Q

Clotting factor 3 Name and Origin…

A

Tissue factor thromboplastin, Perivascular tissue

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5
Q

Clotting factor 4 Name and Origin…

A

Calcium, Plasma

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6
Q

Clotting factor 5 Name and Origin…

A

Proaccelerin (Labile factor), Liver

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7
Q

Clotting factor 7 Name and Origin…

A

Proconvertin (stable factor)

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8
Q

Clotting factor 8 Name and Origin…

A

“Antihemophilic factor A” or “Antihemopilic globulin”, Liver

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9
Q

Clotting factor 9 Name and Origin…

A

“Antihemophilic factor B” or “Christmas factor”, Liver

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10
Q

Clotting factor 10 Name and Origin…

A

Stuart-Prower factor, liver

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11
Q

Clotting factor 11 Name and Origin…

Name associated disease…

A

“Plasma Thromboplastin antecedent”, Liver

associated with Hemophilia C, and Rosenthal syndrome

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12
Q

Clotting factor 12 Name and Origin…

A

Hageman factor

Liver, Platelets

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13
Q

Clotting factor 13 Name and Origin…

A

Fibrin Stabilizing factor, or Lake-lorand factor

Platelets, plasma

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14
Q

Extrinsic Mechanism basic steps

A

Damage to Perivascular tissue»>
Thromboplastin (Factor 3)»>
Factor 7»>

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15
Q

Intrinsic pathway basic steps

A 
Platelets>>>
Factor 12>>>
Factor 11>>>
Factor 9>>>
Factor 8>>>
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16
Q

Common Pathway Mechanism Basic steps

A 
Factor 10>>>
Prothrombin activator>>>
Prothrombin (Factor 2)>>>
Thrombin>>>
Fibrinogen (Factor 1)>>>
Fibrin>>>
Fibrin Polymer (clot)
17
Q

Extra factors involved with the Extrinsic pathway

A

Ca2+ and Factor V involved

18
Q

Extra factors involved with the intrinsic pathway

A

Ca2+, and PF3 involved

19
Q

Extra factors involved with the common pathway

A 
Factor 3
Factor 4
Ca2+ (involved 2 times)
PF3
Factor 13
20
Q

Vitamin K dependent clothing factors

A

2, 7, 9, and 10

ASDOH Hematology (6 decks)

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