Clostridium Flashcards
Module 4
Causative agent of Tetanus
Clostridium tetani
Morphology of Clostridium
Straight, slender rod shaped (Gram variable)
True or False,
Clostridium does not ferment Carbohydrates
True
3 toxins produced by Clostridium tetani
- Tetanospasmin
- Tetanolysin
- Peripherally active non-spasmogenic toxin
What toxin produced by Clostridium tetani is responsible for characteristic feature of tetanus
Tetanospasmin
What toxin produced by Clostridium tetani is responsible for local tissue necrosis favorable for multiplication
Tetanolysin
Travel route of Tetanospasmin
Nerve trunk to Spinal Cord
Tetanospasmin inhibits the release of ________ which is a transmitter substance responsible for inhibitory nerve network of spinal cord
Glycine
Portals of entry of Clostridium tetani
- Nail wounds in horses
- Castration
- Calving, dehorning, nose ringing (Cattle)
- Autointoxication
- Umbilical Cord in Newborns
This toxin produced by Clostridium tetani has a paralytic action on PNS and inactivation of inhibitory nerve network
Tetanospasmin
This species of Clostridium is a source of potent neurotoxin characterized by Flaccid Paralysis
Clostridium botulinum
Morphology of Clostridium botulinum
Oval spores, centric and eccentric
Major Metabolic End product of all strains
Acetic Acid
This toxin consists of hemagglutinin moiety
Botulism toxin
True or False,
Botulism toxin is released during lysis of cell
True
Disease caused by Clostridium perfringens A
Yellow Lamb Disease
Disease caused by Clostridium perfringens E
Enterotoxemia in lambs and calves
What clostridia causes necrotic enteritis of sheep
Clostridium perfringens C
Disease caused by Clostridium perfringens B
Lamb dysentery, hemorrhagic enteritis of sheep and goats
What clostridia causes redwater disease infectious icterohemoglobinuria
Clostridium hemolyticum
What clostridia causes black leg, black quarter, quarter evil, symptomatic anthrax
C. chauvoei
What clostridia causes malignant edema Braxy or bradsot
C. septicum
Disease caused by Clostridium novyi
Big head in rams Black disease
Disease caused by Clostridium difficile
Enterotoxemia in hamsters
What clostridia is responsible for Ulcerative enteritis or quail disease
C. colinum
Disease caused by Clostridium villosum
Subcutaneous abscesses in cats
Synonyms of Clostridium perfringens
C. welchii, Gas Bacillus, Welch bacillus
What is the phospholipase C produced by Clostridium perfringens
Lecithinase
What species of clostridia is Clostridium hemolyticum closely related to
C. novyi (Type D)
Other name of Clostridium chauvoei
Clostridium feseri
Other name of Clostridium septicum
Ghon-Sachs bacillus
4 toxins of Clostridium perfringens
Alpha, Beta, Epsilon, Iota
Clostridium botulinum strain A causes this disease in chickens
Botulism
Clostridium botulinum strain C causes this disease in Ducks and wild birds
Limberneck, Western Duck disease
What strain of C. botulinum causes Lamsiekte/Lame sickness in cattle
Clostridium botulinum strain D
This disease is characterized by dysphagia tremors, weakness, recumbency followed by death
Shaker foal syndrome
