Clostridium Flashcards

Module 4

1
Q

Causative agent of Tetanus

A

Clostridium tetani

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2
Q

Morphology of Clostridium

A

Straight, slender rod shaped (Gram variable)

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3
Q

True or False,

Clostridium does not ferment Carbohydrates

A

True

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4
Q

3 toxins produced by Clostridium tetani

A
  1. Tetanospasmin
  2. Tetanolysin
  3. Peripherally active non-spasmogenic toxin
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5
Q

What toxin produced by Clostridium tetani is responsible for characteristic feature of tetanus

A

Tetanospasmin

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6
Q

What toxin produced by Clostridium tetani is responsible for local tissue necrosis favorable for multiplication

A

Tetanolysin

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7
Q

Travel route of Tetanospasmin

A

Nerve trunk to Spinal Cord

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8
Q

Tetanospasmin inhibits the release of ________ which is a transmitter substance responsible for inhibitory nerve network of spinal cord

A

Glycine

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9
Q

Portals of entry of Clostridium tetani

A
  1. Nail wounds in horses
  2. Castration
  3. Calving, dehorning, nose ringing (Cattle)
  4. Autointoxication
  5. Umbilical Cord in Newborns
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10
Q

This toxin produced by Clostridium tetani has a paralytic action on PNS and inactivation of inhibitory nerve network

A

Tetanospasmin

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11
Q

This species of Clostridium is a source of potent neurotoxin characterized by Flaccid Paralysis

A

Clostridium botulinum

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12
Q

Morphology of Clostridium botulinum

A

Oval spores, centric and eccentric

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13
Q

Major Metabolic End product of all strains

A

Acetic Acid

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14
Q

This toxin consists of hemagglutinin moiety

A

Botulism toxin

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15
Q

True or False,

Botulism toxin is released during lysis of cell

A

True

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16
Q

Disease caused by Clostridium perfringens A

A

Yellow Lamb Disease

17
Q

Disease caused by Clostridium perfringens E

A

Enterotoxemia in lambs and calves

18
Q

What clostridia causes necrotic enteritis of sheep

A

Clostridium perfringens C

19
Q

Disease caused by Clostridium perfringens B

A

Lamb dysentery, hemorrhagic enteritis of sheep and goats

20
Q

What clostridia causes redwater disease infectious icterohemoglobinuria

A

Clostridium hemolyticum

21
Q

What clostridia causes black leg, black quarter, quarter evil, symptomatic anthrax

A

C. chauvoei

22
Q

What clostridia causes malignant edema Braxy or bradsot

A

C. septicum

23
Q

Disease caused by Clostridium novyi

A

Big head in rams Black disease

24
Q

Disease caused by Clostridium difficile

A

Enterotoxemia in hamsters

25
Q

What clostridia is responsible for Ulcerative enteritis or quail disease

A

C. colinum

26
Q

Disease caused by Clostridium villosum

A

Subcutaneous abscesses in cats

27
Q

Synonyms of Clostridium perfringens

A

C. welchii, Gas Bacillus, Welch bacillus

28
Q

What is the phospholipase C produced by Clostridium perfringens

A

Lecithinase

29
Q

What species of clostridia is Clostridium hemolyticum closely related to

A

C. novyi (Type D)

30
Q

Other name of Clostridium chauvoei

A

Clostridium feseri

31
Q

Other name of Clostridium septicum

A

Ghon-Sachs bacillus

32
Q

4 toxins of Clostridium perfringens

A

Alpha, Beta, Epsilon, Iota

33
Q

Clostridium botulinum strain A causes this disease in chickens

A

Botulism

34
Q

Clostridium botulinum strain C causes this disease in Ducks and wild birds

A

Limberneck, Western Duck disease

35
Q

What strain of C. botulinum causes Lamsiekte/Lame sickness in cattle

A

Clostridium botulinum strain D

36
Q

This disease is characterized by dysphagia tremors, weakness, recumbency followed by death

A

Shaker foal syndrome