Bacillus Flashcards

Module 3

1
Q

Most pathogenic species of the Genus Bacillus

A

Bacillus Anthracis

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2
Q

Morphology of Bacillus

A

Large rod shaped, Gram positive

(Bacillus anthracis forms long chains in cultures with square ends)

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3
Q

Major anthrax enzootic zones

A

India, Pakistan, Africa, South America, Philippines

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4
Q

What is the component of capsule of Bacillus

A

Polymers of D-glutamic acid and some polysaccharide

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5
Q

What are the toxin complex or holotoxin

A
  1. Edema Factor
  2. Protective Antigen
  3. Lethal Factor
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6
Q

Net effect of Holotoxin

A
  1. Kills phagocytes
  2. Increase capillary cell permeability
  3. Damage clotting mechanism
  4. Inhibit bactericidal activity of Serum
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7
Q

Forms of Anthrax

A
  1. Localized
  2. Generalized
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8
Q

What form of anthrax is a wound on skin, cutaneous, malignant carbuncle or pustule

A

Localized Anthrax

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9
Q

This form of anthrax is an airborne spore; woolsorter’s disease

A

Generalized Anthrax

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10
Q

Symptoms of Anthrax

A

Edema, Shock, Hemorrhage before death

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11
Q

This diagnosis stains the organism blue and capsules pink

A

McFadyean’s stain

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12
Q

This diagnosis detects capsular antigen

A

Agar Gel Precipitation Test

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13
Q

This diagnosis results to a Medusa-Head or judge wig type

A

Ground glass-like non-hemolytic colonies on Blood Agar Plate

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14
Q

Organisms grow with cell wall impairment due to

A

Presence of Penicillin

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15
Q

What bacteriophage can Lyse B. anthracis

A

Gamma phage

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16
Q
A