ClinPath 4 - csv Flashcards

1
Q
  1. Replicative form of chlamydia
A

Reticulate body

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2
Q
  1. Infectious stage of chlamydia
A

Elementary body

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3
Q
  1. The target cell of R. Rickettsii
A

Vascular endothelium

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4
Q

4.Ornithosis

A

Chlamydophila psittaci

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5
Q
  1. Cell Lines used for diagnosis of Chlamydia infections
A

Mcoy and Buffalo Green Monkey Cells (both)

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6
Q
  1. B. Quintana
A

Trench Fever

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7
Q
  1. Fried egg colonies
A

Mycoplasma

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8
Q
  1. Chlamydia trachomatis can cause one of the following conditions
A

Both (ocular and genital disease)

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9
Q
  1. Antigen detected in chlamydial infection
A

LPS antigen

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10
Q
  1. Horder Spots
A

C. psittaci

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11
Q
  1. This organ was named TWAR?
A

C. pneumoniae

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12
Q
  1. AR39 is associated with?
A

From throat of a student with Pharyngitis

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13
Q
  1. TW-183
A

Isolated from eye of a control child in a trachoma vaccine

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14
Q
  1. IgM Antibody incubation period of C.pneumoniae
A

1-2 weeks (pero sa notes 2-3 weeks)

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15
Q
  1. Black ESCHAR suggests the presence of the ff infection?
A

C. Rickettsial Infection

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16
Q
  1. Rickettsial spp. Replication takes place in the?
A

Cytoplasm

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17
Q
  1. Rickettsial organism has
A

Gram negative cell wall

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18
Q

18 Most severe form of rickettsial infection:

A

endemic murine epidemic rmsf

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19
Q
  1. Rickettsia Prowazeki
A

Epidemic Typhus

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20
Q
  1. Rickettsia rickettsii
A

RMSF (rocky mountain spotted fever)

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21
Q
  1. Rickettsia typhi
A

murine typhus

22
Q
  1. Bartonella quintana
A

Trench fever

23
Q
  1. Bartonella henselae
A

Cat scratch disease

24
Q
  1. Which of the ff tumor markers is classified as a tumor suppressor gene?
A

BRCA1

25
Q
  1. Which of the following is the most useful in using tumor analysis?
A

Monitoring recurrence

26
Q
  1. Which is used for recurrence of ovarian cancer?
A

CA-125

27
Q
  1. Which of the following tumor maker is used to monitor persons with breast cancer for recurrence of disease.
A

CA-15-3

28
Q
  1. Tumor marker used to determine the usefulness of herceptin therapy in breast cancer
A

HER2

29
Q
  1. A person is suspected of having testicular cancer. Which type of hCG test would be most useful?
A

Plasma immunoassay for intact hCG and b-hCG subunit

30
Q
  1. Mild illness, wheezing, coryza and pneumonia is suggestive of?
A

Mycoplasma infection

31
Q
  1. Considered as the smallest living organism.
A

Mycoplasma

32
Q
  1. Increase Alpha Fetoprotein is usually associated with
A

Hepatocellular carcinoma

33
Q
  1. Which of the following assays is recommended as a screening test for colorectal cancer in persons over 50 years old?
A

Occult blood

34
Q
  1. Which of the following assay is used to determine the risk for development of cancer?
A

P53 gene mutation

35
Q
  1. Which of the following is true about PSA?
A

Free PSA below 25% is nonmalignant

36
Q

36 Tumor marker as screening tool

A

PSA

37
Q
  1. 65 yr old male with hemochromatosis, inadequately treated, status post left colon resection. On routine examination CEA level is elevated. CT scan shows no mass lesion. What is the likely reason for this?
A

Impaired liver function

38
Q
  1. Tumor marker used for HEPATOCELLULAR CARCINOMA. in China:
A

AFP

39
Q
  1. Tumor marker occurring in epithelial cells that become elevated during malignancies except
A

CEA

40
Q
  1. Polypeptide hormone:
A

Alkaline phosphatase

41
Q
  1. Mutation of p53 can be detected through:
A

PCR

42
Q
  1. Tumor marker for the screening and identification of families or high-risk individuals
A

BRCA 1

43
Q
  1. Recommendation for ordering tumor marker tests:
A

Order serial test in same laboratory using the same assay kit.

44
Q
  1. Ectopic Tumor Marker EXCEPT:
A

CEA

45
Q
  1. Female with sudden change on her bowel movement, no lesion on rectal area, positive on occult blood test, presence of 6cm mass. What tumor marker should be used?
A

CA 19-9

46
Q
  1. Organ specific tumor marker.
A

PSA

47
Q
  1. Which tumor marker is associated with Lewis Blood group?
A

CA 19-9

48
Q
  1. A 79 yr old woman, previously healthy. Palpated a lump in her upper outer quadrant breast. Histologic test shows pleomorphic cells with increase N:C ratio and prominent nucleoli. Immunologic test shows negative HER2/neu, positive estrogen receptor, positive c. D marker. HER2/neu is indicative of?
A

Good Prognosis

49
Q
  1. A 50 yr old man has had headaches and difficulty concentrating for the past 2 months. He then begins to exhibit odd behavior. He suffers a grand mass tissue and the sample is submitted to the hospital. MRI reveals a large mass with extensive necrosis in the left cerebral hemisphere. Which of the following tumor marker is most likely used?
A

Desmosterol

50
Q
  1. A 50 yr old woman has headache. Has 5kg wt. Loss for the last few months, has decreased menstruation over the past 10 days, the physical examination, bilateral papiledema was noted. Ct scan revealed a marked decreased cerebral edema with effacement of lateral ventricles. Lab shows, Na 108, k 4.o cl 83 co2 14 glucose 82 creatinine 0.5 Which tumor markers is useful?
A

CgA