ClinPath 4 - csv Flashcards
- Replicative form of chlamydia
Reticulate body
- Infectious stage of chlamydia
Elementary body
- The target cell of R. Rickettsii
Vascular endothelium
4.Ornithosis
Chlamydophila psittaci
- Cell Lines used for diagnosis of Chlamydia infections
Mcoy and Buffalo Green Monkey Cells (both)
- B. Quintana
Trench Fever
- Fried egg colonies
Mycoplasma
- Chlamydia trachomatis can cause one of the following conditions
Both (ocular and genital disease)
- Antigen detected in chlamydial infection
LPS antigen
- Horder Spots
C. psittaci
- This organ was named TWAR?
C. pneumoniae
- AR39 is associated with?
From throat of a student with Pharyngitis
- TW-183
Isolated from eye of a control child in a trachoma vaccine
- IgM Antibody incubation period of C.pneumoniae
1-2 weeks (pero sa notes 2-3 weeks)
- Black ESCHAR suggests the presence of the ff infection?
C. Rickettsial Infection
- Rickettsial spp. Replication takes place in the?
Cytoplasm
- Rickettsial organism has
Gram negative cell wall
18 Most severe form of rickettsial infection:
endemic murine epidemic rmsf
- Rickettsia Prowazeki
Epidemic Typhus
- Rickettsia rickettsii
RMSF (rocky mountain spotted fever)
- Rickettsia typhi
murine typhus
- Bartonella quintana
Trench fever
- Bartonella henselae
Cat scratch disease
- Which of the ff tumor markers is classified as a tumor suppressor gene?
BRCA1
- Which of the following is the most useful in using tumor analysis?
Monitoring recurrence
- Which is used for recurrence of ovarian cancer?
CA-125
- Which of the following tumor maker is used to monitor persons with breast cancer for recurrence of disease.
CA-15-3
- Tumor marker used to determine the usefulness of herceptin therapy in breast cancer
HER2
- A person is suspected of having testicular cancer. Which type of hCG test would be most useful?
Plasma immunoassay for intact hCG and b-hCG subunit
- Mild illness, wheezing, coryza and pneumonia is suggestive of?
Mycoplasma infection
- Considered as the smallest living organism.
Mycoplasma
- Increase Alpha Fetoprotein is usually associated with
Hepatocellular carcinoma
- Which of the following assays is recommended as a screening test for colorectal cancer in persons over 50 years old?
Occult blood
- Which of the following assay is used to determine the risk for development of cancer?
P53 gene mutation
- Which of the following is true about PSA?
Free PSA below 25% is nonmalignant
36 Tumor marker as screening tool
PSA
- 65 yr old male with hemochromatosis, inadequately treated, status post left colon resection. On routine examination CEA level is elevated. CT scan shows no mass lesion. What is the likely reason for this?
Impaired liver function
- Tumor marker used for HEPATOCELLULAR CARCINOMA. in China:
AFP
- Tumor marker occurring in epithelial cells that become elevated during malignancies except
CEA
- Polypeptide hormone:
Alkaline phosphatase
- Mutation of p53 can be detected through:
PCR
- Tumor marker for the screening and identification of families or high-risk individuals
BRCA 1
- Recommendation for ordering tumor marker tests:
Order serial test in same laboratory using the same assay kit.
- Ectopic Tumor Marker EXCEPT:
CEA
- Female with sudden change on her bowel movement, no lesion on rectal area, positive on occult blood test, presence of 6cm mass. What tumor marker should be used?
CA 19-9
- Organ specific tumor marker.
PSA
- Which tumor marker is associated with Lewis Blood group?
CA 19-9
- A 79 yr old woman, previously healthy. Palpated a lump in her upper outer quadrant breast. Histologic test shows pleomorphic cells with increase N:C ratio and prominent nucleoli. Immunologic test shows negative HER2/neu, positive estrogen receptor, positive c. D marker. HER2/neu is indicative of?
Good Prognosis
- A 50 yr old man has had headaches and difficulty concentrating for the past 2 months. He then begins to exhibit odd behavior. He suffers a grand mass tissue and the sample is submitted to the hospital. MRI reveals a large mass with extensive necrosis in the left cerebral hemisphere. Which of the following tumor marker is most likely used?
Desmosterol
- A 50 yr old woman has headache. Has 5kg wt. Loss for the last few months, has decreased menstruation over the past 10 days, the physical examination, bilateral papiledema was noted. Ct scan revealed a marked decreased cerebral edema with effacement of lateral ventricles. Lab shows, Na 108, k 4.o cl 83 co2 14 glucose 82 creatinine 0.5 Which tumor markers is useful?
CgA
