Clinical Syndromes Flashcards
Causes of necrotising fasciitis?
Treatment?
Group A strep
May be polymicrobial
Ben pen, clinda +/- meropenem
+/- IVIG
SURGERY
Mycobacterium ulcerans?
Victoria - Bairnsdale, Phillip Island, Point Lonsdale, Daintree
Rifampicin + moxifloxacin for 8 weeks
+/- surgery
Infections with TNF-alpha inhibitors?
TB Listeriosis Aspergillosis Candida CMV HBV HSV VZV PCP Cryptococcus Nocardia
Disease from Tropheryma whipplei?
Whipple's Disease Large joint arthragia Weight loss Diarrhoea Abdominal pain
PCR
Treatment = Ceftriaxone then bactrim
Cat Scratch Disease?
Bartonella species infection
Cat bite or scratch
Cutaneous lesion –> lymphadenopathy
Resolves with ceftriaxone and gent over 1-4 months
Other diseases caused by bartonella?
Bactaemia Endocarditis Trench fever Bacillary angiomatosis Spenitis Oroya fever
Infection from HHV-6?
Roseola infantum or febrile seizures Febrile illness Haemophagocytic syndrome Hepatitis Encephalitis
Severe in transplantation patients
Infection from HHV-8
Kaposi’s sarcoma
Body cavity lymphoma
Castleman’s syndrome
Only in immunosuppression
STI and vertical transmission
Features of disseminated gonococcaemia?
Fever, rash, polyarthritis, tenosynovitis
Infective arthritis in young people
Infections from group A strep?
Impetigo
Cellulitis
Nec fasc
Features of Toxic shock syndrome?
Toxin producing staph - usually from tampon
–> flucloxicillin and clindamycin
Strep pyogenes - wounds
–> Ben pen and clindamycin
What is Lemerre’s syndrome?
Causes by Fusobacterium Necrophorum or strep - pharyngeal infections
Thrombophebitis of the internal jugular vein –> infective emboli
Treat for 6-8weeks IV antibiotics
What is the importance of staphlococcus lugdunensis?
Same as staph aureus - positive culture is always important!
Treat with IV antibiotics for 2 weeks +
What is first line for diabetic foot infections?
Pipercillin-tazobactam
Covers psuedomonas
