Clinical - Pulmonary Mycosis Flashcards
What is the presentation of histoplasmosis?
Acute pneumonia
ARDS, disseminated infection, mediastinal granuloma, mediastinal fibrosis, broncholithiasis
How do you treat histoplasmosis?
Amphotericin B for severe life threatening cases
Itraconazole for non-life threatening cases
Where is coccidioidomycosis found?
San Joaquin Valley
How does coccidiomycosis present?
Erythema nodosum, arthralgia, eosinophilia, acute pneumonia, chronic cavitary disease
How do you treat coccidiomycosis?
Amphotericin B for severe manifestation and pregnant
Fluconazole for meningitis
Where is blastomycosis found?
Southern, south central, and Great Lakes
What organs does blastomycosis affect?
Lung, skin, bone, male genitalia, CNS
How do you treat blastomycosis?
Amphotericin B for severe life threatening cases
Itraconazole for non-life threatening cases
Both for 6 months
Who is at risk for sporotrichosis?
Florists, horticulturists, gardeners
What are the signs of sporotrichosis?
Lymphangitis of skin and nodule
Chronic pneumonitis with cavitation and empyema or meningitis
How is sporotrichosis transmitted?
Cutaneous inoculation
Inhalation
How do you treat sporotrichosis?
Itraconazole for lymphatic or cutaneous
Amphotericin B for disseminated
How does invasive aspergillosis present in immunocompromised?
Presents in granulocytopenic patients with hematologic malignancy
Fever, pulmonary infiltrates, neutropenia and Hodkins
What is a fungal ball?
Invasions of aspergillosis that colonize the repiratory tract
What are the symptoms of a fungal ball?
Hemoptysis, weight loss, cough, fever with neutropenia