Clinical Pharmacology Exam II Flashcards
In general, hepatobiliary therapeutics include ____, ____, and _____ treatments,
What are some common goals for symptomatic therapy of hepatobiliary diseases?
List some of the different gastroprotectants we use as a supportive treatment for patients with hepatobiliary disease.
List some of the different appetite stimulants we use as a supportive treatment for patients with hepatobiliary disease.
List some of the different antiemetics we use as a supportive treatment for patients with hepatobiliary disease.
How do we detoxify or remove intestinal toxins to decrease the symptoms of HE?
What are some drugs we use to control seizure management in our patients with HE?
How do we manage ascites in our patients with hepatobiliary disease?
How do we manage coagulopathies in our patients with hepatobiliary disease?
What are the primary goals of our systemic and hepatobiliary specific treatments for patients with hepatic disease?
Briefly describe how we modify anesthesia for patients with liver disease.
How do we modify fluid therapy for patients with ascites?
How do we modify fluid therapy for patients with hepatic insufficiency/PSS?
How do we modify fluid therapy for patients with hepatic failure?
How do we modify fluid therapy for patients with hepatic lipidosis?
How do we modify fluid therapy for patients with hepatic encephalopathy?
Why do we tend to reach for colloid fluids in our patients with hepatic disease?
List some of the different antioxidants we use in our patients with hepatitis disease.
List some of the different water soluble vitamins we use in our patients with hepatitis disease.
List some of the different fat soluble vitamins we use in our patients with hepatitis disease.
Briefly describe the role and complexity of the hepatic antioxidant system.
Describe the roles that thiols play in the hepatic antioxidant system.
Why do we want to support hepatic GSH in patients with liver disease?
Describe NAC as an antioxidant that we supplement in patients with liver disease.
Describe SAMe as an antioxidant that we supplement in patients with liver disease.
What are the 4 core effects of ursodiol?
What are the uses and side effects of ursodiol?
What are some of the different antifibrotic agents we user in our patients with hepatic disease?
What is the mechanism of action of colchicine?
What are the indications for colchicine? What are the side effects?
Describe the use of polyunsaturated phosphatidylcholine in patients with hepatic disease.
Describe the use of milk thistle in patients with hepatic disease.
What are the different anti-inflammatory drugs we may use in patients with hepatobiliary disease?
Advantageous combination therapy in necroinflammatory and cholestatic liver disorders may include _____, other _____ or _____ prescription drugs combined with various _____.
Adjunctive therapy with an effective ____ and ____ may optimize control of inflammatory mediator release and cell response as compared to pure immunomodulatory treatment or therapy limited to antioxidants.
Describe the use of antibiotics in patients with hepatobiliary disease.
List the different immunosuppressant drugs we use in our patients with hepatobiliary disease.
List some of the different drugs we use in patterns with copper hepatopathy.
What are the different effects of zinc?
When should we consider supplementing zinc in our patients with hepatobiliary disease? What are the side effects?
Name and describe the different copper chelating drugs we use in patients with copper hepatopathy.
Describe your fluid therapy plan for a cat with hepatic lipidosis.
Describe your nutritional support plan for a cat with hepatic lipidosis.
List some of the different adjuvant therapies you would use in a cat with hepatic lipidosis.
Lay out an appropriate treatment plan for feline cholangiohepatitis.
Lay out an appropriate treatment plan for feline neutrophilic CCHS.
Lay out an appropriate treatment plan for feline non-neutrophilic CCHS.
What are our goals when treating canine chronic hepatitis?
Lay out a comprehensive treatment plan for canine chronic hepatitis.
