Clinical Management of Arrhythmias Flashcards
What is an arrhythmia?
Abnormal heart beat
What can arrhythmias be defined as?
Too fast
Too slow
Extra beats
Missed beats
What is bradycardia?
<60 bpm
What is tachycardia?
> 100 bpm
What is associated with tachyarrhythmia?
Atrial fibrillation
Atrial flutter
Supraventricular tachycardia
Ventricular tachycardia
Ventricular fibrillation
What are the different types of atrial fibrillation?
Paroxysmal AF
Persistent AF
Permanent AF
What is paroxysmal AF?
Episode stops within 48hrs without treatment
What is persistent AF?
Episode lasts >7 days
What is permanent AF?
Present all the time
What is supraventricular tachycardia?
Fault in electrical impulses above ventricles
What is associated with bradyarrhythmia?
Sick sinus syndrome
Heart block
What are the different types of arrhythmias?
Premature heartbeats
Premature atrial contractions
Premature ventricular contractions
What does arrhythmias present as?
SYMPTOMS
Fluttering sensation in chest
SOB
Dizziness
Fatigue
Fainting
Sweating
Anxiety
What are the causes?
Coronary artery disease
High B.P= uncontrolled
Diabetes
Caffeine
Thyroid toxicosis
Alcohol
Smoking
ACS
Valvular disease
What are the complications of arrhythmias?
Stroke
Heart failure
Sudden death
What is an ischaemic stroke?
Ischaemic tissue from clot = artery blocked
What is a haemorrhage stroke?
Clot bursts = bleed in brain
What is catheter ablation?
Pushed into heart to find where impulse is coming from
Create scar tissue = doesn’t conduct
Which drugs are used for rate control?
Beta blockers
CCB
Cardiac glycoside
What is an example of a beta blocker you would use?
Bisoprolol
What is an example of CCB you would use?
Diltiazem
Verapamil
What is an example of cardiac glycoside you would use?
Digoxin
Which drug would you use to control rhythm?
Amiodarone
What do you council a patient on taking beta blockers?
Fatigue
Nightmares
Cold peripheries
Bronchospasm
Mask hypoglycaemia = diabetes
Bradycardia
What does anticoagulation do?
Inhibit blood clotting pathways
What do the NICE guidelines say about anticoagulate?
NOT for those under 65
+ NO other risk factors other than sex
When do you consider anticoagulation with CHA2DS2-VASc score?
1 for males with AF
2 or above for females with AF
What are the types of anticoagulants?
DOACS
Warfarin (vitamin K antagonist)
Heparins/low molecular weight heparins = injections
What is aspirin?
Anti-platelet
= used when plaque is involved
What is CHA2DS2-VASc?
C = congestive heart failure
H = hypertension
A2 = age > 75 (scores 2)
D = diabetes
S2 = stroke (scores 2)
V = vascular disease
A = age 65-74
S = sex (female)
What is in a Trimbow inhaler?
Steroid
LABA
LAMA
What is the assessment for bleeding?
ORBIT
When do you NOT use DOAC for anticoagulation?
> 120kg
How long does Warfarin take to work?
2-3 days
Because Warfarin takes 2-3days to work, what does this mean?
Offer another anti-coagulant till it is a correct level in system
CALLED BRIDGING
How does Warfarin work?
Inhibit vitamin K epoxide
= decrease clotting factors
What colour Warfarin tablet is 0.5mg?
White
What colour Warfarin tablet is 1mg?
Brown
What colour Warfarin tablet is 3mg?
Blue
What colour Warfarin tablet is 5mg?
Pink
What does the INR scale mean?
INR = 1 = normal
INR = 2 = 2x longer takes to clot than normal
And so on … 3, 4, 5
What is the yellow book?
Patients on Warfarin should always carry it around with them
Says dose, indication, range, INR, hospital + ect
What is a contraindication of DOACS?
Mechanical heart valve
Why is amiodarone a high risk medication?
Extensive side effect profile
Very long t1/2
What does amiodarone interact with?
CYP enzyme inhibitor
QT prolongation
Hypokalaemia
Drugs lowering HR
What are the side effects of amiodarone?
Night time glare
Blindness
Photosensitivity
Slate grey skin
Scarring in lungs
Hypo/hyperthyroidism
Unhealthy liver
Peripheral neuropathy
What are the loading dose for amiodarone?
100mg 3x a day for 7 days
100mg 2x a day for 7 days
200mg 1x a day so after
What are the side effects of Warfarin?
Increased time of bless
Painful skin rash
What does Warfarin interact with?
CYP450 inhibitors/inducers
Alcohol
Herbal medication
Food - leafy greens, liver
Antibiotics
What does DOACS interact with?
CYP450 inhibitors/inducers