clinical examples ( lecture 1 )

Question 1

what is wilsons disease

Answer 1

an inherited disorder in which excessive amounts of copper accumulate in the body, particularly in the liver, brain, and eyes.

Question 2

what is shown on T2WI MRI for wilsons disease

Answer 2

hyperintensities due to copper depositions in the bilateral basal ganglia and thalami

Question 3

what is glioblastoma multiforme- GMB

Answer 3

a fast-growing and aggressive tumor in the brain
that presents with the following symptoms:
- inabilty to make decisions
- persistent headache
- diplopia
- vomitting
- loss of apetite
- change in behaviour and personality and mood
- difficulty in speech
- new onset of seizures
-

Question 4

what can be seen on T1WI/T2WI mri for GBM

Answer 4

ring enhancement
irregular boarders
butterfly shape = if spreads
necrotic centre

Question 5

what are metastatic brain tumours

Answer 5

Tumors that spread to the brain from a primary neoplasm located in other organs of the body are referred to as metastatic brain tumors.

Question 6

what would you seen on an mri for metastatic brain tumors

Answer 6

multiple lesions in diffrent areas on the body as they’ve spread

Question 7

what is multiple sclerosis

Answer 7

a condition that can affect the brain and spinal cord, causing a wide range of potential symptoms, including problems with vision, arm or leg movement, sensation or balance.

Question 8

what is seen on mri ( T2WI ) for MS

Answer 8

white matter lesions are bright, especiallly in corpus callosum and periventricular regions.