Clinical correlates Flashcards
1
Q
Most common enzyme defect in glycolysis
Sx: chronic hemolytic anemia
A
Pyruvate kinase deficiency
2
Q
Low exercise capacity, particularly on high CHO diet
A
Muscle Phosphofructokinase Deficiency
3
Q
Most common biochem cause of lactic acidosis
X-linked DOMINANT
Sx: psychomotor retardation
Tx: ketogenic diet
A
Pyruvate dehydrogenase deficiency
4
Q
Deficiency that occurs with chronic alcoholism
A
Thiamine deficiency
5
Q
Inhibits pyruvate dehydrogenase by binding to lipoic acid
A
Arsenic poisoning
