2nd messenger systems Flashcards
1
Q
G protein involved in cAMP pathway
A
Gs: inc cAMP
Gi: dec cAMP
Adenylate cyclase
2
Q
Protein kinase in cAMP pathway
A
protein kinase A
3
Q
Examples in cAMP pathway
A
glucagon
epi (a2,b1)
4
Q
G proteins in IP3/DAG
A
Gq
phospholipase C
5
Q
Protein kinase in IP3/DAG
A
Protein kinase C
6
Q
Example in IP3/DAG pathway
A
epi (a1)
7
Q
Protein kinase in cGMP
A
Protein kinase G
8
Q
Example on cGMP pathway
A
ANP
NO
9
Q
Protein kinase in tyrosine kinase pathway
A
tyrosine kinase/ JAK-STAT
10
Q
Example in tyrosine kinase pathway
A
Insulin
Growth factors
11
Q
Example in intracellular pathway
A
glucocorticoids
thyroid hormones
12
Q
The 5 2nd messenger systems
A
cAMP IP3/ DAG cGMP Tyrosine kinase Intracellular