Clinical Considerations in Antiypertensive therapy (Dr. D'AMico) Flashcards

1
Q

individuals who are normotensive at 55 years of age have a _____-lifetime risk for developing hypertension

A

90%

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2
Q

what is normal hypertension

A

120/80

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3
Q

what is prehypertension

A

129-139 or diast 80-89

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4
Q

what are the criteria for stage 1 hypertension

A

syst BP 140-159 or diast of 90-99

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5
Q

what are the criteria for stage 2 hypertension

A

syst BP greater than 160, and diast greater than 100

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6
Q

what are the three main risks for hypertension

A

retinopathy
kidney disease
cardiovascular disease

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7
Q

primary hypertension is also known as

A

essential or idiopathic hypertension

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8
Q

according to JNC 7 patients who are normal or prehypertensive should be treated how

A

only with encouragement of lifestyle modification

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9
Q

if patient has coronary artery disease/previous MI the desirable agents are

A

ACE inhibitor or Angiotensin receptor blocker and beta blocker

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10
Q

if patient has systolic heart failure what are the deriable agents

A

ACE inhibitor, ARB if intol to ACE, thiazide
Aldosterone antagonist
Beta blocker if stable

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11
Q

what are the LESS desirable agents for systolic heart failure

A

non-dihydropyridine calcium channel blockers

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12
Q

what are the desirable agents in patients with diastolic heart failure

A

ACE inhibitor or ARB
Thiazide diuretic
Beta Blocker (if stable)

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13
Q

what are the desirable agents for patients with diabetes

A

ACEI or ARB
thiazide
Beta blocker
Nondihydropyridine calcium channel blocker

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14
Q

what are the desirable agents for chronic kidney disease

A

ACEI or ARB but…ACE contraindcated in bilateral renal artery stenosis and ARB caution in hyperkalemia

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15
Q

what are the desirable agents for previous stroke or TIA

A

ACEI or ARB

thiazide diruetic

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16
Q

what are the desirable agents for for exertional l angina

A

beta blocker and calcium channel blocker

17
Q

what are the less desirable for patients with exertional angina

A

direct vasodilators or short acting dihydropyridine calcium channel blockers

18
Q

what are the desirable agents for Prinzmetals variant angina

A

calcium channel blocker

19
Q

what are the LESS desirable agents for prinzmetals variant angina

A

beta blockers

20
Q

number one side effect of ACE inhibitor is

A

cough

21
Q

what are the less desirable agents for comorbid conditions

A
thiazide diuretics (except indapamide)
beta blockers (esp. non-cardioselective beta blockers)
22
Q

what facilitates angioedema

A

build up of bradykinin

23
Q

what are the desirable agents for dyslipidemia

A

Alpha blocker
ACEI or ARB
calcium channel blocker
indapamide

24
Q

what are the desirable agents for patients with osteoporosis

A

thiazide diruetic

25
Q

what are the desirable agents for benign prostatic hypertrophy

A

alpha blocker

26
Q

desirable agents in migraine cephalgia

A

beta blockers (non-cardioselective) and Nondihydopyridine calcium channel blocker

27
Q

what drug should be avoided in gout patients

A

thiazide diruetics

28
Q

what drugs should be avoided in asthma, severe chronic obstructive lung disease

A

beta blockers

29
Q

what drugs should be avoided in patients who have current or history f depression

A

central alpha agonists
reserpine
beta blockers

30
Q

what are the desirable agents for pregnancy hypertension

A

methyl dopa

hydralazine

31
Q

what drugs should be avoided in pregnancy

A

ACEI and ARB’s

32
Q

what are the agents that should be less desirable agnet for individuals who are physically active or atheles

A

high dose diuretics

beta blockers

33
Q

what agents should be avoided in sexually active men

A

beta blockers

thiazide diuretic

34
Q

what agents should be avoided in truck drivers

A

central alpha agonists

dirueticss

35
Q

what are the desirable agents for african americans

A

thiaxide diruetics and calcium channel blockers

36
Q

what are the less desirable agents for african americans

A

ACI and ARBS

37
Q

what are the agents that are desirable for

A

thiazide diruetics

dihydropyridien calcium channel blockers

38
Q

what drugs should be avoided in the elderly with orthostatic hypertension

A

avoid/use with caution alpha blockers