Clinical Cohort Studies

Question 1

When does the ‘clinical phase’ of a disease begin?

Answer 1

begins at signs and symptoms of the disease

Question 2

What are the three components of a clinical cohort study?

Answer 2

• Defined group of patients
• At a defined point in the natural history of the disease
• Followed up to assess defined endpoints

Question 3

What does ‘ censored mean’ ?

Answer 3

• Censored means we know that the patient survived their melanoma at least this long- dropped out of the study
• We don’t know how much longer they would survive because we don’t have enough follow-up (2), they were lost to follow-up (3) or died of something else (4)

Question 4

what is the difference between prevalence and incidence ?

Answer 4

prevalence = snapshot in time (ex. 3/100 people died)

incidence = rate of things occuring (1 person died every year)

Question 5

all cohort studies measure what?

Answer 5

all cohort studies measure risk factors