CLINICAL CARE OF THE SKIN, HAIR AND NAILS Flashcards
What is an inflammation of a hair follicle that can occur anywhere on the body where hair is found?
Folliculitis
Folliculitis is most frequently due to what bacteria?
S. aureus (+/- MRSA)
Strep species, pseudomonas also contribute
These are what kind of causes of folliculitis ?
- Dermatophytic
- Pityrosporum on upper chest and back
- Candida albicans
Fungal
What are viral causes of folliculitis ?
- HSV
2. Molluscum contagiosum
What are some parasitic causes of folliculitis?
- Demodex spp. Mites
2. Schistosomes
What are the non infectious causes of Folliculitis?
- PFB
2. Mechanical Folliculitis (Skinny Jeans Syndrome)
The following are all risk factors for what?
- Hair removal
- Other pruritic skin conditions: eczema, scabies
- Occlusive dressing or clothing
- Personal carrier or contact with MRSA
- DM
- Immunosuppression
- Use of hot tubs or saunas
- Chronic antibiotic use
- Tattoos
- Poor hygiene
Folliculitis
What is an abrupt onset of follicular erythematous papules or pustules, with pruritis and pain in hair areas; rash occurs on hair-bearing skin, especially the face (beard), proximal limbs, scalp, and pubis?
Folliculitis
What form of folliculitis appears as a widespread rash, mainly on the trunk and limbs?
Pseudomonal Folliculitis
What is the clinical hallmark of folliculitis ?
Hair emanating from the center of a pustule
True or False
The diagnosis for folliculitis is made clinically
True
What is the treatment of folliculitis?
- Antiseptic and supportive care is usually enough.
- Good hygiene practices
- Wash hands
- Wash towels, clothes, and linens frequently
- Good hair removal practices
- Use witch hazel, alcohol, or tend skin afterward
What is the treatment for Staphylococcal folliculitis?
- Mupirocin ointment applied TID for 10 days
- Cephalexin: 250-500 mg PO QID (7-10 days)
- Dicloxacillin: 250-500 mg PO QID (7-10 days)
Folliculitis
What is the treatment for MRSA?
- Bactrim DS: 1-2 tablets BID PO (5-10 days)
- Clindamycin: 300 mg PO TID (10 to 14 days)
- Doxycycline: 50-100 mg PO BID (5-10 days)
What is the treatment for Pseudomonas folliculitis?
- Ciprofloxacin: 500 to 750 mg PO BID for 7 to 14 days if lesions are
persistent - High-potency topical corticosteroids for inflammation
- Antihistamines (hydroxyzine, cetirizine) to control itching
What is the treatment for Fungal Folliculitis?
- Topical antifungals: ketoconazole 2% cream or shampoo or selenium
sulfide shampoo daily - Systemic antifungals for relapses fluconazole (100 to 200 mg/day for 3 weeks) or itraconazole (200 mg/day for 1 week) or griseofulvin (500 mg/day for 2 to 4 weeks)
What is the treatment for Parasitic folliculitis?
- 5% permethrin: Apply to affected area, leave on for 8 hours, and wash off.
What is the treatment for Herpetic Folliculitis?
- Valacyclovir: 500 mg PO TID for 5 to 10 days
2. Acyclovir: 200 mg PO 5 times daily for 5 to 10 days
What is the primary complication of folliculitis?
Recurrent folliculitis
What is a condition caused by ingrowing hairs, mostly in the beard area (neck area is typically most severe)?
Pseudofolliculitis Barbae
What condition affects people with curly hair or those with hair follicles oriented at an oblique angle to the skin surface, a sharp, shaved, tapered hair re-enters the skins as it grows from below the skin surface and induces a foreign body reaction, producing a micro-abscess?
Pseudofolliculitis Barbae
What condition presents with red papules or pustules that can be both painful and or pruritic, occurs in any area where the hair is shaved, scarring and hyper pigmentation may result from this condition?
Pseudofolliculitis barbae
Keloid formation is often a problem in what condition, especially in African-American people?
Pseudofolliculitis Barbae
PFB is found in ___% to ___% of blacks and __% to ___% of whites who shave
- 50%-75%
2. 3%- 5%
What is treatment approach 1 for PFB?
Medical treatment with grooming standard modifications
What is treatment approach 1 for PFB (mild to moderate)?
Medical treatment with Grooming modifications
The treatment of what consists of the combined use of: application of medicated creams to make hairs more shaveable, shaving with gentle equipment and shaving techniques to minimize the risk of irritation and hair re-entry into the skin?
Mild to Moderate PFB
What is treatment approach 2 for PFB (moderate to severe PFB)?
Laser hair reduction with grooming modification
True or False
Where available, laser hair reduction is the most reliable approach allowing a return to grooming standards. This is an appropriate treatment for moderate to severe cases of PFB or any case desiring permanent hair reduction.
True
Laser Treatment of PFB
A series of at least ____ treatments is usually needed, with ___ to ___ days between treatments. This procedure is usually available at military medical treatment facilities with a dermatology department.
- Three
2. 30-45 days
What are the complications of PFB?
Abscess formation and scarring
What is a contagious, superficial, intra-epidermal infection occurring prominently on the exposed areas of the face and extremities?
Impetigo
What form of Impetigo is the invasion of previously healthy skin?
Primary Impetigo (pyoderma)
What form of Impetigo is an invasion at sites of minor trauma (abrasions, insect bites, underlying eczema) and can be considered to be S. aureus Impetigo of hair follicles?
Secondary Impetigo (impetiginization)
True or False
Impetigo may present with S. Aureus alone or combined with Group A beta-hemolytic streptococci
True
What is known as a deeper, ulcerated impetigo infection often with lymphadenitis?
Ecthyma
What are the synonyms for Impetigo?
- Pyoderma
- Impetigo contagiosa
- Impetigo vulgaris
What is the most common form of impetigo, presenting with the formation of vesiculpustules that rupture, leading to crusting with a characteristic golden appearance; some local lymphadenopathy may occur?
Nonbullous impetigo
What is a staphylococcal impetigo that progresses from small to large flaccid bullae (newborns/young children) caused by epidermolytic toxin release; ruptured bullae leaving brown crust; less lymphadenopathy; trunk is most often affected in <30% of patients?
Bullae Impetigo
These are all risk factors associated with what condition?
- Warm humid environment
- Tropical or subtropical climate
- Summer or Fall season
- Minor trauma, insect bites, breaches in skin
- Poor hygiene, poverty, crowding, epidemics, wartime
- Familial spread
- Complications of pediculosis, scabies, chicken pox, eczema/atopic dermatitis
- Contact dermatitis
- Burns
- Contact sports
- Children in day care
- Carriage of Group A Strep and S. Aureus
Impetigo
What is a cutaneous pyoderma characterized by thickly crusted erosions or ulceration, usually a consequence of neglected impetigo and classically evolves in impetigo occluded by footwear and clothing?
Ecthyma
True or False
Impetigo Treatment
Treatment speeds healing, improves cosmetic appearance, and avoids spread of disease. Avoidance of infection spread is the key; hand washing is vital, especially for reducing spread in children.
True
What can be used to help prevent impetigo at the sites of minor skin trauma?
Mupirocin ointment TID
Impetigo Treatment
Remove crusts, clean with gentle washing ___ to ___ times daily, and clean with antibacterial soap, chlorhexidine, or Betadine
2-3 times daily
Impetigo treatment
What is the treatment for Vanilla Staph?
Nonbullous (minor spread, treat 7 days; widespread, treat 10 days); bullous (treat 10 days)
- Mupirocin (Bactroban) 2% topical ointment applied TID for 5 to 7 days (nonbullous only)
- Dicloxacillin: Adult 250 mg PO QID
Impetigo treatment
What is the treatment for MRSA?
- Clindamycin, tetracyclines, or trimethoprim-sulfamethoxazole. Oral
doses given for 7 days are usually sufficient. - Clindamycin 300 mg q6-8h
What is the disposition for a patient with Impetigo?
- Full duty or modified duty
2. Dependent on location, distribution, and extent
What is an acute bacterial infection of the dermis and subcutaneous (sc) tissue and is typically caused by bacterial penetration through a break in the skin?
Cellulitis
What infection of the skin presents with these 4 classic signs of inflammation?
- Erythema
- Edema
- Tenderness to palpation
- Elevated skin temperature surrounding area of infection
Cellulitis
What skin infection typically has unilateral lower-extremity involvement with systemic symptoms usually being absent, the most common portal of entry of this for the lower leg is the toe web intertrigo with fissuring ?
Cellulitis
True or False
Cellulitis typically occurs near surgical wounds and trauma sites
True
A patient presents with a wound to the lower left leg with itching and burning; he is running a fever and reports chills and malaise over the past 4 days. He has some localized pain and tenderness with erythema, induration, swelling and warmth to the site. Regional lymphadenopathy and purulent drainage is noted as well. What is the most likely diagnosis?
Cellulitis
The following is the treatment for what?
- Demarcate area w/ sharpie to measure progress once treatment is started
- Immobilize and elevate involved limb to reduce swelling
- Sterile saline dressing or cool aluminum acetate compresses for pain relief
- Compression stocking for edema
- Tylenol +/- NSAIDS for pain relief
- Tetanus if needed (especially if there is an open traumatic wound)
Cellulitis
What is the antimicrobial treatment for Non-purulent cellulitis?
(target treatment toward beta-hemolytic streptococci and MSSA)
- Cephalexin 500mg PO q6H
2. Dicloxacillin 500mg PO q6H
What is the antimicrobial treatment for Purulent cellulitis?
probable CA-MRSA
- Clindamycin 450mg PO
- Trimethoprim-sulfamethoxazole (TMP-SMX) 1 DS tab PO BID
- Doxycycline 100 mg PO BID
What is the antimicrobial treatment for cellulitis secondary to a human or animal bite?
Amoxicillin + clavulanic acid (Augmentin)
MEDADVICE needs to be considered when for cellulitis?
- Elevated WBC with marked left shift
- Failure to respond to oral antibiotics
- Severe infection, suspicion of deep or rapidly spreading infection, tissue necrosis, or severe pain
- Worsening symptoms that do not resolve/improve after 24 - 48 hrs of therapy
True or False
Cellulitis of the hands and face my require hospitalization
TRUE TRUE TRUE
What are rare and rapidly progressing infections involving any layer of the soft tissue including the skin, subcutaneous fat, fascia, and or muscle; associated with extensive tissue destruction, systemic toxicity, limb loss and are potentially fatal; and represents a MEDICAL EMERGENCY?
Necrotizing Soft Tissue Infections (NSTI)
These can all be risk factors for what tissue infection?
- Major penetrating trauma
- Minor laceration or blunt trauma (muscle strain, sprain, or contusion)
- Skin breach (varicella lesion, insect bite, injection drug use)
- Recent surgery
- Mucosal breach (hemorrhoids, rectal fissures, episiotomy)
- Immunosuppression
- Malignancy
- Obesity
- Alcoholism
Necrotizing Fasciitis
Where does necrotizing fasciitis most frequently occur?
extremities (predilection for the lower leg)
May mimic DVT
In what skin infection will you see and initial presentation of pain, erythema, edema, cellulitis and a high fever; pain is usually progressive, relentless, and severe and is often out of proportion to the severity of the physical findings?
Necrotizing Fasciitis
The skin exam for what may be unrevealing early on, or may be even confused with cellulitis or abscess; you may see blistering, crepitus, soft tissue edema, erythema, discoloration, necrosis, bullae, vesicles, or ulceration?
Necrotizing fasciitis
An MRI for a patient with Necrotizing fasciitis may show what?
Edema along the fascial plane
Cultures for necrotizing fasciitis may show what bacteria?
Group A strep and mixed aerobic and anaerobic bacteria
What is the cornerstone of treatment for necrotizing fasciitis ?
Prompt and wide surgical debridement
may require amputation
What should be administered once the diagnosis of Necrotizing soft tissue infections (NSTI) is suspected?
Broad spectrum antibiotics
Should cover gram positive, negative and anaerobic organisms
What is the main adjunctive therapy to surgery when a patient has Necrotizing fasciitis?
Antibiotics
What is the disposition for a patient with Necrotizing Fasciitis?
IMMEDIATE MEDEVAC
True or False
Necrotizing Fasciitis
Close contacts of patients and health care workers require chemoprophylaxis with antibiotics after being exposed
False
Do not require chemoprophylaxis (good to brief COC on)
What is a well-circumscribed, painful, inflammatory nodule at any site that contains hair follicles, may extend into the dermis and subcutaneous tissues?
Furuncle (aka Boil)
What is a collection of pus within the dermis and deeper skin tissues and manifests as a painful, tender, fluctuant, and erythematous nodules?
Typically no systemic symptoms
Skin abscess
What is a coalescence of several inflamed follicles into a single inflammatory mass with purulent drainage from multiple follicles?
Typically presents with systemic symptoms and fever
Carbuncle
The following is the etiology and pathophysiology of what?
- infection spreads away from the hair follicle into the surrounding dermis
- pathogen strain of S. aureus or CA-MRSA
Abscess
These are risk factors associated with what?
- Carriage of pathogenic Staphylococcus sp. in nares, skin, axilla, and perineum
- DM, malnutrition, alcoholism, obesity, atopic dermatitis
Abscess
The following is a description of what?
- Deep subcutaneous erythematous papules enlarge to deep seated nodules that can be stable or become fluctuant within several days
- Most commonly occurs on the back of the neck, upper back, and lateral thighs
- Tender perifollicular swelling, terminating in discharge of pus and necrotic plug
Carbuncle
True or False
With a carbuncle, malaise, chills, and fever may precede or occur during the height of inflammation
True
Carbuncle should be handled by ____ or _____ in all situations unless the patient is unable to be transferred
dermatology or general surgery
What systemic antibiotic therapy is used to cover MSSA with a patient with an Abscess?
- Dicloxacillin 250-500mg QID for 10 Days
- Cephalexin 250-500mg QID for 10 Days
- Amoxicillin and Clavulanate (Augmentin) 875 mg BID for 10 days
What systemic antibiotic therapy is used to cover MRSA with a patient with an Abscess?
- Doxycycline 100 mg BID
- Trimethoprim-Sulfamethoxazole DS BID
- Clindamycin 150-300 mg BID for 10 days
Abscess
What lab test is indicated if a patient has a fever or signs/symptoms of systemic disease?
CBC
What are the most common benign cutaneous cysts?
Epidermal Cysts
aka Epidermoid cysts, epidermal inclusion cysts, or improperly sebaceous cysts
What can occur anywhere on the body and the size ranges from a few millimeters to several centimeters in diameter, the wall of consists of normal stratified squamous epithelium derived from the follicular infundibulum?
Epidermal cysts
True or False
Cysts can be primary (de novo) or may arise of the implantation of the follicular epithelium in the dermis as a result of trauma or from a comedone
True
What is usually a firm or fluctuant flesh-to-yellow colored solitary nodule (0.5 to 5 cm) which often connects with the surface by keratin filled pores, grow slowly over time and may remain stable for months to years, and are commonly located in the face, neck, upper back, and chest; if due to trauma, on buttocks, palms or plantar side of the feet?
Stable epidermal cyst
True or False
Inflamed/Ruptured Epidermal Cyst
Inflamed epidermal cysts are warm, red and boggy and TTP; sterile purulent material and keratin debris often point toward and drain to the surface
True
What lesions often mimic and present very similarly to abscesses?
Inflamed/ruptured epidermal cysts
Do asymptomatic epidermal cysts require treatment?
Nope
True or False
Epidermal Cyst Disposition
Duty status is based on location, severity, and control of the infection. Wound should be checked throughout treatment to ensure symptoms improvement and adequate drainage/healing
True
What is the most common benign mesenchymal neoplasm in adults and are composed of mature white adipocytes?
Lipoma
What can occur on any part of the body and usually develop superficially in the subcutaneous tissue, may often occur on the neck, trunk, and on other extremities and is composed of fat cells?
Lipoma
True or False
Malignant transformation of a lipoma into a liposarcoma is common
False
Rare
What should be done for rapidly growing lipomas?
Biopsy
Treatment for lipomas is usually not required, but may be excised by Dermatology for what reasons?
- Cosmetic
- Pain
- Impedance of duties
True or False
Classic lipomas are entirely benign and recur only rarely
True
Intramuscular/intermuscular lipomas have a recurrence rate of up to what percentage?
20%
What is an acute inflammatory process, with or without abscess formation, that involves the proximal and lateral nail folds that has been present for less than 6 weeks?
Paronychia
What is most commonly caused by S. Aureus, Streptococcus pyogenes infection in the periungual tissue by minor mechanical or chemical traumas that disrupt the nail fold barrier?
Paronychia
What are some common factors contributing to paronychia?
- Manicuring
- Nail biting
- Thumb sucking
- Picking a hangnail
What is the most common infection of the hand, representing 35% of all hand infections in the United States?
Paronychia
What usually develops along the nail margin (proximal and lateral nail folds) manifesting over hours to days with pain, warmth, redness, and swelling?
Paronychia
What is the early treatment for paronychia?
Warm compresses and soaks
What is the disposition for a patient with paronychia?
LLD may be indicated based on occupation and treatment
What is an abscess of the distal phalanx fat pad, S aureus is the most common pathogen, patient usually presents with a painful and swollen distal pulp space?
Felon
What is a pyogenic infection of the distal pulp space, with pus collecting in the spaces formed by the vertical septa anchoring the pad to the distal phalanx?
Felon
nearly always follows minor finger injury
What condition is characterized by severe pain, exquisite tenderness, and tense swelling of the distal digit with erythema, may have a visible collection of pus or palpable fluctuance; underlying bone, joint or flexor tendons may become infected?
Felon
What is the treatment for a felon?
- Prompt incision with division of the fibrous septa to ensure adequate drainage
- Should be performed by Derm if available
- IDC should treat with antibiotics
a. MSSA- Dicloxacillin or Keflex
b. MRSA- Trimethoprim/sulfamethoxazole, clindamycin, or doxy - Rest and immobilization
- Elevation
What is the spectrum of cutaneous infections caused by Candida yeast?
Candidiasis
True or False
Candida acts as an opportunistic pathogen when allowed to overgrow and predisposing conditions permit
True
True or False
Yeast infects only the outer layers of the epithelium of the mucous membrane and skin (stratum corneum)
True
What are some synonyms for candidiasis?
- Monilia
- Thrush
- Yeast
- Intertrigo
These are all risk factors associated with what?
- Hormonal alteration of the skin microbiome
- Elimination of competing microorganisms
- Physical environmental changes
- Direct/indirect immunosuppression
Candidiasis and fungal infections
What occurs mostly in intertriginous areas such as the axillae, groin, digital web spaces, glans penis, and beneath the breasts; manifesting as pruritic, well-demarcated, erythematous patches of varying size and shape?
Candidiasis
The primary patches of what may have adjacent satellite papules and pustules; the contents of which dissect horizontally under the stratum corneum and then peel it away, resulting in a red, denuded, glistening surface with a long, cigarette paper-like, scaling and advancing border?
Candidiasis
True or False
Oral candidiasis is adults can be the first sign of HIV
True
What is the treatment for candidiasis?
- affected skin should be kept dry and exposed to air as much as possible
- Topical Azole class antifungals
- Allylamine class antifungals
a. Terbinafine (Lamisil)
What is the treatment for Vaginal candidiasis?
- First line (topical)
a. clotrimazole vaginal cream
b. miconazole nitrate vaginal cream - Second line (oral)
a. fluconazole (Diflucan)
What kind of fungal infection involves the crural fold and gluteal cleft?
Tinea Cruris
What kind of fungal infection involves the face, trunk, and/or extremities; often presents with ring shaped lesions, hence the misnomer ringworm?
Tinea Corporis
What kind of fungal infection involves the face, trunk, and/or extremities; often presents with ring shaped lesions, hence the misnomer ringworm?
Tinea Corporis
What kind of fungal infection involves the face, trunk, and/or extremities; often presents with ring shaped lesions, hence the misnomer ringworm?
Tinea Corporis
What fungal infection involves the scalp and hair; affected areas of the scalp can show characteristic black dots resulting from broken hairs?
Tinea Capitis
What is the cause of Tinea infections that can subsist on protein, namely keratin and can cause disease in keratin-rich structures such as skin, hair, and nails?
Dermatophytes
What are anthropophilic infections?
Infections acquired from personal contact
What form of tinea will present with scaling, round or oval pruritic plaques characterized by a sharply defined annular pattern with peripheral activity and central clearing (ring shaped lesions), the papules and occasionally the pustules/vesicles present at the border, and less commonly at the center?
Tinea Corporis
How long should treatment for Tinea Corporis be continued for after the resolution of the infection?
1 week
What oral medication can be used for Tinea Corporis?
Griseofulvin (ultra-microsize) 250 po mg QD x 2 weeks or
Fluconazole 150 mg once a week for 3-4 weeks.
What form is Tinea is well-marginated, erythematous, halfmoon-shaped plaques in crural folds that spread to the medial thighs, advancing border is well defined, often with fine scaling and sometimes vesicular eruptions; lesions are often bilateral and do not include scrotum/penis (unlike candida)?
Tinea Cruris
Can tinea cruris migrate to the perineum, perianal area, and gluteal cleft and onto the buttocks in chronic/progressive cases?
Yes
What is the first line treatment of tinea cruris?
Topical antifungal creams applied 2 times a day for 10 to 14 days