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Antimicrobial Drugs 2 - Protein synthesis inhibitors > Clindamycin > Flashcards

Clindamycin Flashcards

1
Q

Mechanism

A

Binds 50s subunit; inhibits translocation (like macrolides)

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2
Q

Adverse effects

A

Associated with higher incidence of gastrointestinal superinfection (C. difficile) -> vancomycin or metronidazole

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3
Q

Uses of clindamycin

A

Gram - aerobes resistant
**Penicillin resistant strep (S. pyogenes necrotizing fascitis)
Wound infections in penicillin allergic pt

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Antimicrobial Drugs 2 - Protein synthesis inhibitors (4 decks)

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