Cleft Palate-Craniofacial anamolies; Embryological developement

Question 1

Embryo

Answer 1

0-9 weeks

Question 2

Fetus

Answer 2

9 weeks-birth

Question 3

Neonate

Answer 3

birth-1 month

Question 4

Infant

Answer 4

1 month-2 years

Question 5

Process of egg fertilization

Answer 5

Meiosis—gamete—mitosis—

Question 6

Zygote

Answer 6

sperm and egg, initial one cell organism

Question 7

Segmentation

Answer 7

cell dividing and creating daughter cells (cleavage), meiosis

Question 8

Blastomere

Answer 8

Zygote after the first cell division takes place

Question 9

Morula

Answer 9

3 days post-fertilization to roughly 6 days

Question 10

Blastocyst

Answer 10

6 days
Differentiation between 6-8 days, Tropoblast forms, outer layer contains inner cell mass and attaches to uterine wall- becomes cord and placenta
Trophoblast is when things can go wrong, problems with differentiation

Question 11

Gastrulation

Answer 11

9-12 days- inner cell mass turns inside out to create a hollow core

Question 12

Embryonic disk

Answer 12

12 days- cell differentiation and gastrulation create 3 layers of cells, all become part of body (organs are usually combinations)
Ectoderm- outer layer: teeth, nervous system
Mezoderm- middle layer: connective tissues, bone, cartilage, muscle, blood
Endoderm- inner layer: lining of tracts, interior with no air contact

Question 13

Syndrome

Answer 13

a constellation of symptoms that all have the same root cause

Question 14

Sequence

Answer 14

Dominos, no single cause. (Pierre Robins)

Question 15

Dysmorphology

Answer 15

Individual does not look symmetrical

Question 16

Most common defect

Answer 16

Clefting
1 in every 30,000 births
Can be isolated or part of a syndrome