classical pathway

Question 1

Recognition unit

A. C4
B. C1 (ab)C1q

Answer 1

B. C1 (ab)C1q

Question 2

Activation unit

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 2

C4, C2,C3

Question 3

membrane attack complex in classical pathway

Answer 3

C5->C9

Question 4

Binds to FC Igm and IgG

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 4

B.C1q

Question 5

Cleaves c2 and c4

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 5

C1s

Question 6

Activate c1s
A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 6

C 1r

Question 7

Part of C3 convertase C4b

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 7

C4

Question 8

Binds to C4b-form c3 convertase

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 8

C2

Question 9

key intermediate in all pathway, most concentrated component
A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 9

C3

Question 10

initiates membrane attack complex

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
C. C5
I. c6
J.c7
K.c8
L.c9

Answer 10

C5

Question 11

Binds to C5b IN MAC

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 11

C 6

Question 12

Bind to c5bc6 in mac

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 12

C7

Question 13

starts pore formation on membrane

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 13

C8

Question 14

polymerizes to cause cell lysis

A. C1
B.C1q
C.C1r
D.c1s
E. C4
F. c2
G. C3
H. C5
I. c6
J.c7
K.c8
L.c9

Answer 14

c 9

Question 15

-Specific immune system
- The main ab- directed mechanism for triggering complement activation

A. Lectin pathway
B.classical path

Answer 15

B classical

Question 16

ONLY IgM and IgG activates complement in classical pathway EXCEPT

A.IgG4
B.IgG2

Answer 16

A.IgG4