Antibody classes Flashcards
predominant antibody in secondary/anamnestic Immune response
A. IgA
B. IgG
C. IgM
D. IgD
E.Ig E
IgG
Warm antibodies are
serum half life of 5 days
A. IgA
B. IgG
C. IgM
D. IgD
E.Ig E
IgG
numbered according to their abundance in the serum In IgG
IgG1 > IgG2>IgG3> IgG4
most efficient in crossing the placenta
A.IgG1
B. IgG2
C.IgG3
D. IgG4
IgG1
cant cross the placenta
A.IgG1
B. IgG2
C.IgG3
D. IgG4
IgG2
most efficient incomplement fixation and has longest hinge region
A.IgG1
B. IgG2
C.IgG3
D. IgG4
IgG3
cant fix complement
A.IgG1
B. IgG2
C.IgG3
D. IgG4
IgG4
predominant in body secretions in tears, saliva, Colostrum, milk and intestinal fluid
A. IgA
B. Ig G
C.Igm
IGA
subclass of IgA that has serum;monomer
A. IgA1
B. IgA2
IgA1
subclass of IgA that has secretions; dimer and held by J Chain
A. IgA1
B. IgA2
IGA2
Protects IgA from digestion by proteolytic enzymes and
facilitate transport of lgA to mucosal surfaces.
Secretory component
It is known as primary response antibody
A. Igm
B.IgG
Igm
the cold reacting Antibody
IgM
*IgM**
How many Ag binding sites are available for effector functions due to steric hindrances
A.1-6
B.5-6
C.4-6
. B. 5-6
First Ab that is formed by the fetus
IgM
most efficient Ab that activates complements
Igm
Immunoregulation AB
IgD
It is found on the surface of mature and naive B cells in association with Igm
A.IgM
B. IgD
C. IgE
IgD
The least abundant immunoglobulin in the serum
A.IGE
B. IgA
C.IgG
D.IgD
IgE
Plays an important role in Ag recognition by B cells
A.IGE
B. IgA
C.IgG
D.IgD
IgD
Extremely susceptible to proteolysis (due to unusual long hinge
A.IGE
B. IgA
C.IgG
D.IgD
IgD
The most Heat labile antibody, originally called Reagenic
ANTIBODY
A. IgE
B.IgD
C.IgD
IgE
What antibody
Mediates some types of hypersensitivity (allergic) reactions, allergies, and anaphylaxisand is generally responsible for an individual’s immunity to invading parasites
IgE
