classic presentation Flashcards
athlete with polycythemia
secondary to EPO injection
back pain, fever, night sweats
Pott’s disease
bone pain, bone enlargement, arthritis
Paget’s Disease of bone
chest pain, pericardial effusion/friction rub, persistant fever following MI
Dressler Syndrome (autoimmune fibrinous pericarditis, weeks/months post MI)
chest pain with ST depression
unstable angina (normal troponin), NSTEMI subendocardial infarct (elevated troponin)
child with fever later develops red rash on face and then on body
erythema infectiosum - parvovirus B19
chorioretinitis, hydrocephalus, intracranial calcification
congenital toxoplasmosis
cutaneous/dermal edema due to connective tissue deposition
myxedema of hypothyroidism
pretibial myxedema of graves
dog or cat bite infection
pasturella multocida cellulitis
dysphagia/esophageal web, iron deficiency, glossitis
Plummer Vinson syndrome (increased risk esophageal SCC)
erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cell
Mycosis fungiodes (cutaneaous T cell lymphoma) Sezary syndrome (mycosis fungiodes with malignant T cells in blood
fever, chills, headache, myalgia following Abx treatment for syphilis
Jarisch Herxheimer reaction - lysis of spirochete and endotoxin release
fibrous plaque on penis and abnormal curvature
peyronie disease
hyperphagia, hyperorality, hypersexuality, hyperdocility
Kluver Bucy syndrome (bilateral loss of amygdala)
hypoxemia, polycythemia, hypercapnea
chronic bronchitis (blue bloater)
infant with hypoglycemia and hepatomegaly
von gierke (glucose 6 phosphatase; severe), Cori disease (debranching enzyme; milder)
jaundice, palpable distended, non tender gallbladder
Courvoisier sign - obstruction of biliary tree due to cancer of pancreatic head
mucosal bleeding and prolonged BT
Glanzmann thrombasthemia (GPIIb/IIIa)
multiple colon polyps, osteomas and soft tissue tumors, impacted/supernumerary teeth
Gardner syndrome (FAP subtype)
painful blue fingers/toes, hemolytic anemia
cold agglutinins (mycoplasma, mononucleosis, CLL)
painful, red raised lesion of pads of fingers and toes
Osler nodes (infectious endocarditis - immune complex deposition)
painless erythematous lesion on palm/soles
Janeway lesion (infectious endocarditis- septic emboli/microabscess)
pink complexion, dyspnea, hyperventiliation
emphysema
polyuria, renal tubular acidosis type 2 (proximal), growth failure, electrolyte imbalance, hypophosphatemic rickets
Fanconi syndrome (non functioning proximal tubule)
rash on palms, soles
coxsackie virus, secondary syphilis, RMSF
recurrent cold abscess, unusual eczema, high IgE
Job hyper IgE (neutrophil chemotaxis abnormality)
retinal hemorrhage with pale center
roth spot (bacterial endocarditis)
severe RLQ on palpation of LLQ
Rovsing sign of acute appendicitis
short stature, cafe au lait spot, thumb/radial defect, leukemia (AML), aplastic anemia
fanconi anemia (loss of cross link repair)
smooth, moist, painless wart like lesion on genitals
condyloma lata of secondary syphilis
swollen, hard painful finger joints
osteoarthritis (heberdens nodes - DIP; bouchard nodes-PIP)
vascular birthmark (portwine stain) on face
nevus flammeus; normally benign unless associated with Sturge Weber
weight loss, diarrhea, arthritis, fever, adenopathy
Whipple disease
