Class/indication Flashcards
Balsalazide
Maintenance or acute ulcerative colitis
Amino salicylate
Mesalazine
Acute or maintenance of IBD Amino salicylate (rectal and oral)
Olsalazine
Acute or maintenance of mild ulcerative colitis
Amino salicylate
Sulfasalazine
Amino salicylate
Mild to severe IBD and active rheumatoid arthritis
Beclometasone
Corticosteroid
Adjunct to amino salicylate in ulcerative colitis
Prophylaxis of asthma
Allergic and vasomotor rhinitis
Management of oral ulceration
0.025% is potent for severe inflammatory skin disorders and psoriasis
Budesonide
Corticosteroid - glucocorticoid
IBD (including foam for ulcerative colitis affecting sigmoid colon and rectum)
Autoimmune hepatitis
Prophylaxis of mild to moderate asthma
Vedolizumab
Anti lymphocyte monoclonal antibody
IBD unresponsive to conventional or TNF inhibitor
Eluxadoline
Antidiarrhoeal antipropulsive
IBS with diarrhoea
Peppermint oil
Antispasmodic
Abdominal colic and distention particularly in IBS
Linaclotide
Guanylate cyclase c receptor agonist laxative
IBS with constipation
Teduglutide
GLP-2 analogue
Short bowel syndrome
Citric acid with magnesium carbonate (citrameg)
Osmotic laxative
Bowel evacuation
Macrogol 3350
Osmotic laxative
Bowel cleansing
Magnesium citrate with sodium picosulfate
Stimulant laxative Bowel evacuation (day be for)
Isphagula husk
Constipation
Bulk forming laxative from 1 month
Methyl cellulose
Bulk forming laxative
Contipation and diarrhoea in adults
Stericula
Bulk forming laxative
Contipation from 6 years old
Lubiprostone
Chloride channel agonist
Chronic idiopathic constipation
Lactulose
Osmotic laxative with 48 hours to act
Contipation from 1 month
Hepatic encephalopathy
Macrogol 3350
Osmotic laxative onset in 24 - 48 hours
Chchronic constipation in adults
Laxido and movicol (with chlorides/bicarbonate) also for foecal impaction
Magnesium hydroxide
Constipation in adults
Osmotic laxative
Prucalopride
Selective serotonin agonist
Chronic constipation
Docusate
Stimulant and softening laxative acting in 1-2 days or 20 minuted (anal)
Chronic constipation
Bisacodyl
Stimulant laxative acting in 10 - 12 hours or 20 - 60 minutes
Contipation
bowel clearance
Senna
Stimulant laxative acting in 8 - 12 hours
Constipation
Sodium picosulfate
Stimulant laxatives with onset in 6 - 12 hours
Constipation
Methylnaltrexone
Opioid induced constipation
Opioid receptor antagonist acts within 30 - 60 mins
Naloxegol
Opioid induced constipation
Opioid receptor antagonist
Loperamide
Diarrhoea
Foecal incontinence
Bowel colic
Racecadotril
Diarrhoea
Enkephalinase inhibitor
Co phenotrope
Diarrhoea and control of consistency following stoma
Antipropulsive
Koalin
Diarrhoea
Intestinal absorbent
Sucralfate
Gastritis, ulceration
Chelate
Cimetidine
Ulceration, oesophagitis, reduce degradation of pancreatic enzyme supplementation
H2 receptor antagonist
Esomeprazole
Proton pump inhibitor
Ulcers, GORD, Zollinger Ellison, h pylori
Lansoprazole
Proton pump inhibitor
H pylori, ulcers, Zollinger Ellison, GORD, oesophagitis, acid related dyspepsia
Dicycloverine
Antimuscarinic
Smooth muscle spasm
Hyoscine
Antimuscarinic
Smooth muscle spasm, IBS, Respiratory secretions, bowel colic
Propantheline
Antimuscarinic
Smooth muscle spasm and anuresis in adults
Alverine
Antispasmodics
Smooth muscle spasm and dysmenorrhoea
Mebeverine
Antispasmodic
IBS or smooth muscle spasm
Chonedeoxycholic acid
Cerebrotenidinous xanthomatosis (inborn errors of bile acid synthesis). Bile acid
Cholic acid
Inborn errors of bile acid synthesis
Bile acid
Obeticholic acid
Bile acid
Biliary cholangitis
Ursodeoxycholic acid
Bile acid
Dissolution of gallstones and biliary cirrhosis
Terlipressin
Vasopressin analogue
Bleeding from oesophageal varices
Naltrexone with bupropion
Adjunct in obesity with dietary measures when bmi above 30 or 27 with Co morbidity
SNRI
Orlistat
Lipase inhibitor
Adjunct in obesity
Disopyramide
Ventricular and supra ventricular arrythmias including after MI. maintain sinus rythmn after cardioversion
Class 1a anti arrythmic
Lidocaine
Class 1b anti arrythmic and anaesthetic
Cardiopulmonary resuscitation (if amiodarone unavailable)
Ventricular arrythmias
Dental practice
Relief of pain in oral regions
Flecainide
Class 1c anti arrythmic
Supra ventricular and ventricular arrythmias
Propafenone
Class 1c anti arrythmic
Ventricular and paroxysmal supra ventricular arrythmias
Amiodarone
Class 3 anti arrythmic
Arrythmias particularly where other measures ineffective
Dronedarone
Class 3 anti arrythmic
Maintenance of sinus rythmn after cardioversion (paroxysmal or persistent)
Adenosine
Anti arrythmic
Rapid reversion to sinus rythmn in paroxysmal supra ventricular tachycardia
Sotalol
Non selective beta blocker
Ventricular tachyarrythmia
Maintenance of sinus rythmn after cardioversion of AF or flutter
Digoxin
Cardiac glycoside
Heart failure
rapid digitalisation
Tranexamic acid
Antifibrinolytic Local and general fibrinolysis Menorrhagia Hereditary angioedema Epstaxis Prevention and treatment of significant haemorrhage following trauma
Emicizumab
Haemostatic
Prophylaxis of haemorrhage in haemophilia A
Dried prothrombin complex
Coagulation proteins
Treatment and prophylaxis of haemorrhage in factor deficiency
Major bleeding with warfarin following phytomenadione
Idarucizumab
Antidote/chaltor for dabigatran
Aspirin
Antiplatelet
Secondary prevention of cvd (75mg)
ACS (300mg)
Suspected TIA (300mg)
TIA or stroke (75mg daily)
Atrial fibrillation following disabling stroke (300mg daily for 14 days)
Following disabling stroke when recieveing anticoagulation for prosthetic heart valve and risk of haemorrhagic transformation (300mg daily)
Following coronary by pass (75 - 300mg daily)
Mild to moderate pain (300-900mg every 4 to 6 hours. Max 4g)
Clopidogrel
Antiplatelet
Prevention of artherothrombotic events in percutaneous coronary intervention (loading 300/600 mg previous to procedure)
TIA or stroke if aspirin hypersensitive
Prevention of artherothrombotic events in peripheral arterial disease or within 35 days of MI or 6 months of stroke.
After NSTEMI/STEMI
Atrial fibrillation where warfarin unsuitable
Dipyridamole
Secondary prevention fo stroke or thromboembolism with prosthetic valve
antiplatelet
Apixaban
Direct factor xa inhibitor
2.5mg BD following knee (10-14 days) or hip (32 - 38 days) replacement started 12 - 24 hours after surgery
10mg BD for 7 days after VTE then maintenance 5mg BD
2.5mg BD for recurrent after 6 months above.
5mg BD in AF
Edoxaban
Direct reversible inhibitor of factor xa
30 - 60mg daily depending on weight below 61kg for AF and following 5 days of parenteral in VTE
Fondaparinux
Factor X inhibitor Prophylaxis of VTE if major/othro/hip/leg/abdominal surgery Superficial vein thrombosis ACS Treatment of VTE
Rivaroxaban
Factor xa direct inhibitor
10mg daily for 2 (knee) to 5 (hip) weeks in replacement surgery started 6 - 10 hours after surgery
Treatment of VTE - initially 15mg BD for 21 days then 20mg daily
AF
Following ACS with elevated biomarkers
Danaparoid
Heparinoid
Prevention of dvt in general or ortho surgery
Thromboembolic disease with history of heparin induced thrombocytopenia
Dalteparin
LMWH Treatment of VTE Unstable coronary artery disease (different doses depending on risks) Prophylaxis of dvt
Enoxaparin
LMWH
Treatment of VTE, STEMI
Unstable angina and NSTEMI.
Prevention of clotting in extracorporeal circuits
Tinzaparin
LMWH
Treatment of VTE
Prophylaxis of dvt
Prevention of clotting in extracorporeal circuits
Argatroban
Thrombin inhibitor
Anticoagulation in patients with heparin induced thrombocytopenia (different doses if pci, cardiac surgery, warfarin or critically ill)
Bivalirudin
Thrombin inhibitor
Unstable angina, NSTEMI and anticoagulation if having in intervention
Dabigatran
Thrombin inhibitor
110mg 1-4 hours after surgery, then 220mg daily (or 150mg with amiodaron/Verapamil)
Prophylaxis of VTE following knee (9 days after) or hip (27 - 34 days after) replacement
75mg then 150mg in over 75yo
Treatment of prophylaxis of recurrent following parenteral anticoagulant
AF
Urokinase
Tissue plasminogen activators
VTE
Occlusive peripheral artery disease
Occluded central venous catheter or haemodialysis shunts blocked by fibrin clots
Acenocoumarol
Vitamin k antagonists
Prophylaxis of embolization in rheumatic heart disease and atrial fibrillation, inserted prosthetic heart valve, TIA
Phenindione
Prophylaxis of embolization in rheumatic heart disease and atrial fibrillation, inserted prosthetic heart valve
Vitamin k antagonists
Warfarin
Vitamin k antagonists
Prophylaxis of embolization in rheumatic heart disease and atrial fibrillation, inserted prosthetic heart valve and TIA
Clonidine
Centrally acting antihypertensive
Hypertension
Prevention of recurrent migraine, vascular headache, menopausal symptoms (flushing, vasomotor)
Methyldopa
Centrally acting antihypertensive
Moxonidine
Centrally acting antihypertensive
Timolol
Non selective beta blocker Hypertension Angina Prophylaxis after MI Migraine prophylaxis
Reduction of Intra ocular pressure in open angle glaucoma
Acebutolol
Selective beta blocker
Hypertension
Angina
Arrythmias
Atenolol
Selective beta blocker Hypertension Angina Arrythmias Migraine prophylaxis Early intervention within 12 hours of MI
Bisoprolol
Selective beta blocker
Hypertension
Angina
Adjunct in heart failure
Celiprolol
Selective beta blocker
Mild to mod hypertension
Co-tenidone
Atenolol with chlortalidone (thiazide)
Esmolol
Selective beta blocker
Supra ventricular arrythmia
Tachycardia and hypertension in peri op
Metoprolol
Selective beta blocker Hypertension Angina Arrythmias (including in surgery) Migraine prophylaxis Early intervention within 12 hours of the mi Hyperthyroidism
Nebivilol
Selective beta blocker
Hypertension
Adjunct in mild to mod heart failure
Amlodipine
Calcium channel blocker
Prophylaxis of angina
Hypertension
Initially 5mg to max 10mg.
Diltiazem
Calcium channel blocker
Prophylaxis and treatment of angina
Mild to moderate hypertension
Adizem/Angitil/dilcardia/dilzem SR, tildiem retard BD ~ 90 - 120mg up to 180mg
Adizem/angitil/dilzem/viazem XL, slozem, zemtard, tildiem LA OD ~ 180 - 240mg up to 300 - 360mg.
Felodipine
Calcium channel blocker
Prophylaxis of angina
Hypertension
Lacidipine
Calcium channel blocker (dihydropyridine)
Hypertension
Lercanidipine
Dihydropyridine calcium channel blocker
Mild to moderate hypertension
Nicardipine
Dihydropyridine calcium channel blocker
Prophylaxis of angina
Mild to moderate hypertension
Life threatening hypertension (incl neonates and pregnancy)
Nifedipine
Dihydropyridine calcium channel blocker Raynauds syndrome Kawasaki disease Hiccup in palliative care Postponement of premature labour
Angina prophylaxis
Hypertension
Adalat capsules - tds (5mg - 20mg)
Adalat LA, Adipine XL, coracten XL, Valni XL, Fortipine LA 40 OD (30mg to 90mg)
Adipine MR, coracten SR, nifedipress Mr, tensipine MR BD (10mg to 40mg)
Verapamil
Calcium channel blocker
Treatment of supra ventricular arrythmias
Paroxysmal tachyarrhythmia
Prophylaxis of cluster headache
Angina 240mg BD may be reduced to OD
Hypertension 120mg then 240mg OD - 480mg divided
Prophylaxis after MI where beta blockers inappropriate 360MG divided (securon only)
Bendroflumethiazide
Thiazide diuretic
Oedema (5-10mg weekly-daily)
Hypertension (2.5mg daily)
Co-amilozide
Amiloride and hydrochlorothiazide
Hypertension
Congestive heart failure
Oedema and ascites
Indapamide
Thiazide like diuretic
Essential hypertension
Captopril
ACEIs Hypertension Heart failure Within 24 hours of MI Diabetic neuropathy
Enalopril
ACEIs
Hypertension
Heart failure
Prevention of heart failure with left ventricular dysfunction
Lisinopril
ACEIs Hypertension Following MI Renal complications of diabetes Heart failure
Perindopril
ACEIs
Hypertension
Symptomatic heart failure
Following MI
Ramipril
ACEIs Hypertension Symptomatic heart failure Following MI Prevention of cvd Neuropathy
Azilsartan
ARB
Hypertension
Hypertension with intravascular volume depletion
Candesartan
ARB
Hypertension
Hypertension with intravascular volume depletion
Heart failure with impaired left ventricular function when ACEIs not tolerated
Irbesartan
ARB
Hypertension
Hypertension when recieveing haemodialysis
Renal disease in diabetes
Losartan
ARB
Diabetic neuropathy
Chronic heart failure when ACEIs are unsuitable
Hypertension
Hypertension with intravascular volume depletion
Valsartan
ARB
Hypertension
Hypertension with intravascular volume depletion
Heart failure when ACEIs or beta blockers are unsuitable
MI with left ventricular dysfunction /failure
Aliskerin
Renin inhibitor
Essential hypertension
Hydralazine
Vasodilator antihypertensive
Moderate to sever hypertension
Heart failure
Hypertensive emergency
Phenoxybenzamine
Peripheral vasodilator
Hypertension in phaeochromocytoma
Pentolamine
Peripheral vasodilator
Hypertensive episodes in phaeochromocytoma and its diagnosis
Guanethidine
Peripherally acting anti adrenergic
Hypertensive crisis
Sodium nitroprusside
Vasodilator antihypertensive
Hypertensive emergency
Hypotension in anaesthesia
Acute or chronic heart failure
Selexipag
Antiplatelet
Pulmonary arterial hypertension
Iloprost
Cardiovascular prostoglandin
Idiopathic or familial pulmonary arterial hypertension
Ambrisentan
Endothelian receptor antagonists
Pulmonary arterial hypertension
Bosentan
Endothelian receptor antagonists
Pulmonary arterial hypertension
systemic sclerosis with ongoing digital ulcer disease
Riociguat
Guanylate cyclase stimulator
Chronic thromboembolic pulmonary hypertension
Dopamine
Ionotropic sympathomimetics
Cardiogenic shock
Midodrine
Vasoconstricting sympathomimetic
Severe orthostatic hypotension
Noradrenaline
Vasoconstricting sympathomimetic
Acute hypotension
Phenylephrine
Vasoconstricting sympathomimetic
Acute hypotension
Priapism associated with alprostadil
Mydriasis (eye drops)
Eplernone
Aldosterone antagonist
Adjunct in stable patients with LVEF under 40 with HF following MI.
Adjunct in chronic HF with LVEF under 30.
Spironolactone
Aldosterone antagonist
25mg OD;
Moderate to severe HF (to 50mg)
Resistant hypertension
100 - 400mg; Oedema, ascites Malignant ascites Nephrotic syndrome Oedema in CHF Primary hyperaldosteronism
Enoximone
Phosphodiesterase type 3 inhibitors
CHF where cardiac output reduced and filling pressures increased.
Colesevelam
Bile acid sequestrant Primary hypercholstrolemia (with or without statin and ezetimibe)
Colestyramine
Bile acid sequestrant
Hyperlipidaemia
Pruritis in biliary obstruction and cirrhosis
Diarrhoea in chrons, ileal resection, vagotomy, diabetic vagal neuropathy and radiation
Accelerated elimination of teriflunomide/leflunomide
Ezetimibe
Cholesterol absorption inhibitor
Hypercholstrolemia
Bezafibrate
Fibrate (lipid modifying drug)
Hyperlipidaemia if statin not tolerated
Severe hypertriglyceridaemia
Fenofibrate
Fibrate (lipid modifying drug)
Hyperlipidaemia when statin not tolerated
Severe hypertriglyceridaemia
Gemfiibrozil
Fibrate (lipid modifying drug)
Hyperlipidaemia
Hypertriglyceridaemia
Acipimox
Nicotinic. Acid derivative
Hyperlipidaemia not responding
Nicotinic acid
Lipid modifying drug
Adjunct to statin in dyslipidaemia or alone if not tolerated
Atorvastatin
High density statin from 20mg
Hypercholstrolemia
Primary/secondaey prevention of cvd
Fluvastatin
Medium intensity statin at 80mg
Hypercholstrolemia
Prevention of coronary events after percutaneous coronary intervention
Pravastatin
Low intensity statin
Hypercholstrolemia
Prevention of cvd events in previous MI or unstable angina.
Reduction of hyperlipidaemia if recieveing immunosuppression
Rosuvastatin
High intensity statin at 10mg
Hypercholstrolemia
Prevention of cvd events
Simvastatin
High intensity statin at 80mg
Hypercholstrolemia
Prevention of cvd events in cvd or diabetes
Alirocumab
Lipid modifying drug
Hypercholstrolemia a nd dyslipidaemia
Evolocumab
Lipid modifying drug
Hypercholstrolemia /dyslipidaemia
Lomitapide
Lipid modifying drug
Hypercholstrolemia
Cangrelor
Antiplatelet
In combination with aspriirn for reduction of thrombotic events in coronary artery disease undergoing PCI
Abxiximab
Glycoprotein IIB/IIIA inhibitor - antithrombotic
Prevention of ischemic complications when undergoing pci
Short term prevention of MI with unstable angina scheduled for pci
Eptifibatide
Glycoprotein IIB/IIIA INHIBITOR - antithrombotic
In combination with aspirin ad Unfractionated heparin for prevention of early MI with unstable angina or NSTEMI when chest pain within 24 hours.
Tirofiban
Glycoprotein IIB /IIIA inhibitor - antithrombotic
In combination with Unfractionated heparin, aspirin and clopidogrel for prevention of early MI with unstable angina or NSTEMI when chest pain within 12 hours.
Ranolazine
Piperazine derivative
Adjunct for stable angina
Ivabradine
Selective sinus node if inhibitor
Angina
Mild to severe chronic heart failure
Nicorandil
Potassium channel opener
Prophylaxis and treatment of stable angina
Prasugrel
Antiplatelet
In combination with aspirin for preventing artherothrombotic events when undergoing pci
Ticagrelor
Antiplatelet
In combination with aspirin for preventing artherothrombotic events with acs
Alternative to clopidogrel undergoing pci
Alteplase
Fibrinolytics
Acute MI
PE
Ischemic stroke
Streptokinase
Fibrinolytics
Acute MI
VTE
Tenecteplase
Fibrinolytics
Acute MI
Glyceryl trinitrate
Nitrate
Angina. (sublingual spray/tablet may be repeated every 5 minutes intervals and medical attention sought after 3)
Control of hypertension and ichemia after/during surgery
CHF
Anal fissure
Isosorbide dinitrate
Nitrate
Angina
Left ventricular failure
Isosorbide mononitrate
Nitrate
Angina
Dobutamine
Ionotropic sympathomimetics
Support in infarction, surgery, shock and ventilation
Cardiac stress testing
Adrenaline
Vasoconstricting sympathomimetic CPR Acute hypotension Acute anaphylaxis Bradycardia following MI Priapism associated with alprostadil
Bumetanide
Loop diuretics
Oedema
Furosemide
Loop diuretic
Oedema
Resistant hypertension
Torasemide
Loop diuretic
Oedema
Hypertension
Mannitol
Osmotic diuretic
Cerebral oedema
Raised intra ocular pressure
Amiloride
Potassium sparing diuretic
Oedema
Potassium conservation with loop and thiazides
Triamterene
Potassium sparing diuretic
Oedema
Potassium conservation with loop and thiazides
Chlortalidone
Thiazide related diuretic Ascites due to cirrhosis Oedema due to Nephrotic syndrome Hypertension Mild to moderate chronic heart failure Nephrogenic/partial pituitary diabetes insipidus
Metolazone
Thiazide related diuretic
Oedema
Hypertension
Cilostazol
Antiplatelet
Intermittent claudication without rest pain or peripheral tissue necrosis
Inositol
Nicotinic. Acid derivative (lipid modifyer)
Peripheral vascular disease
Moxisylyte
Peripheral vasodilator
Primary Raynauds
Naftidrofuryl
Peripheral vasodilator
Peripheral vascular disease
Cerebral vascular disease
Sodium tetradecyl sulfate
Sclerosant
Reticular/spider/varicose veins
Aclidinium bromide
Inhaled antimuscarinic
COPD maintenance
Glycopyrronium bromide
Inhaled antimuscarinic
COPD maintenance
Hyperhidrosis
Ipratropium bromide
Inhaled antimuscarinic 30-60 minutes onset, duration 3-6h Reversible airway obstruction Acute bronchospams Severe or life threatening acute asthma
Rhinorrhea
Tiotropium
Inhaled antimuscarinic
Maintenance of COPD
Severe asthma
Umeclidinium
Long acting antimuscarinic
Maintenance of COPD
Formoterol
Long acting beta agonists
Chronic asthma
COPD
Indacaterol
Long acting beta agonist
COPD maintenance
Olodaterol
Long acting beta agonist
COPD maintenance
Salmeterol
Long acting beta agonists
COPD
Chronic asthma
Salbutamol
Short acting beta agonists
Asthma
Acute bronchospams
Terbutaline
Short acting beta agonists
Asthma
Exacerbation of reversible Airways obstruction
Uncomplicated premature labour
Fluticasone
Corticosteroid
Prophylaxis of asthma
Allargic rhinitis
Nasal polyps
Potent topical for severe inflammatory skin disorders and psoriasis
Mometasone
Corticosteroids
Prophylaxis of asthma
Allergic rhinitis
Nasal polyps
0.1% cream is potent for severe inflammatory skin disorders and psoriasis
Benralizumab
Monoclonal antibodies
Severe eosinophilic asthma
Mepolizumab
Monoclonal antibodies
Add on for severe refractory eosinophilic asthma
Omalizumab
Monoclonal antibodies
Prophylaxis of severe persistent allergic asthmq
Chronic spontaneous urticaria not responding to antihistamines
Montelukast
Leukotreine receptor antagonists
Prophylaxis of asthma
Seasonal allergic rhinitis with asthma
Nedocromil
Mast cell stabiliser
Prophylaxis of asthma
Sodium cromoglicate
Mast cell stabiliser
Prophylaxis of asthma
Food allergy
Allergic conjunctivitis
Seasonal keratoconjunctivitis
Prophylaxis of allergic rhinitis
Roflumilast
Phosphodiesterase type 4 inhibitor
Severe COPD with chronic bronchitis and exacerbations (adjunct)
Ephedrine
Vasoconstricting sympathomimetic
Reversal of hypotension from spinal or epidural anaesthesia
Neuropathic oedema
Nasal congestion and Sinusitis
Aminophylline
Xanthine
Severe acute asthma
Severe acute exacerbation of COPD
Chronic asthma
Theophylline
Xanthine
Severe acute and chronic asthma
Acrivastine
Non sedating antihistamine
Hayfever, chronic idiopathic urticaria
Cetirizine
Non sedating antihistamine
Hayfever, chronic idiopathic urticaria, atopic dermatitis
Fexofenadine
Non sedating antihistamine
Seasonal allergic rhinitis, chronic idiopathic urticaria
Loratadine
Non sedating antihistamine
Hayfever, chronic idiopathic urticaria
Alimemazine
Sedating antihistamine
Urticaria, Pruritis
Chlorphenamine
Sedating antihistamine
Hayfever, urticaria, food allergy, drug reactions, chickenpox itch
Emergency treatment for anaphylaxis
Clemastine
Sedating antihistamine
Hayfever, urticaria
Hydroxyzine
Sedating antihistamine
Pruritis
Ketotifen
Sedating antihistamine
Allergic rhinitis
Promethazine
Sedating antihistamine
Hayfever, urticaria (and insomnia with it)
Emergency treatment for anaphylaxis
Sedation
Nausea, vomiting, vertigo, motion sickness
C1 esterase inhibitor
Complementary regulatory proteins
Hereditary angioedema
Acetylcysteine
Mucolytic
Reduction of sputum viscosity
Tear deficiency /abnormal mucus (eye drops)
Carbocisteine
Mucolytic
Reduction of sputum viscocity
Dornase alfa
Mucolytics
Cistic fibrosis FVC over 40%
Ivacaftor
Mucolytic
Cystic fibrosis
Mannitol
Mucolytic
Cystic fibrosis as add on therapy
Pholcodine
Cough suppressant
Dry cough
Pirfenidone
Antifibrotic
Mild to moderate idiopathic pulmonary fibrosis
Doxapram
Respiratory stimulants
Post operative respiratory depression
Acute respiratory failure
Donepezil
Centrally acting anticholinesterase
Mild to moderate dementia in alzheimer’s
Galantamine
Centrally acting anticholinesterase
Mild to moderately severe dementia in alzheimer’s
Rivastigmine
Centrally acting anticholinesterase
Mild to moderate dementia in alzheimer’s
Memantine
NMDA receptor antagonists
Moderate ot severe dementia in alzheimer’s
Brivaracetam
Antiepileptic
Adjunct in partial onset seizures with or without secondary generalisation
Carbemazepine
Antiepileptic
Focal and secndarey generalised tonic clinic seizures
Primary generalised tonic clinic seizures
Trigeminal neuralgia
Prophylaxis of bipolar unresponsive to lithium
Adjunct in acute alcohol withdrawal
Diabetic neuropathy
Ethosuximide
Antiepileptic
Absence seizures
Myoclonic seizures
Fosphenytoin
Antiepileptic
Status epilipticus
Seizures associated with neurosurgery or head injury
Gabapentin
Antiepileptic Focal seizures with or without secondary generalisation Peripheral neuropathic pain Migraine prophylaxis Menopause symptoms in breast cancer
Lacosamide
Antiepileptic
Focal seizures with or without secondary generalisation
Lamotrigine
Antiepileptic
Focal, tonic clinic seizures
Seizures associated with lennox gastaut
Bipolar disorder with or without valproate
Levetiracetam
Antiepileptic
Focal, Myoclonic, tonic clinic seizures
Perampanel
Antiepileptic
Adjunct to Focal seizures
Phenytoin
Antiepileptic
Tonic clonic, Focal seizures
Seizures from neurosurgery or head injury
Status epilipticus
Pregabalin
Antiepileptic
Peripheral and central neuropathic pain
Adjunct for Focal seizures
Generalised anxiety disorder
Rufinamide
Antiepileptic
Seizures in lennox gastaut
Sodium valproate
Antiepileptic
All epilepsy
Migraine prophylaxis
Mania
Tiagabine
Antiepileptic
Focal seizures uncontrolled with others
Topiramate
Antiepileptic
Generalised tonic clonic seizures
Seizures associated with lennox gastaut
Migraine prophylaxis
Vigabatrin
Antiepileptic
Adjunct in Focal seizures not controlled with others
Zonisamide
Antiepileptic
Focal seizures
Phenobarbital
Barbiturate antiepileptic
All forms of epilepsy except absence
Status epilipticus
CD3
Primidone
Barbiturate antiepileptic
All forms of epilepsy except absence
Essential tremor
Clobazam
Benzodiazepine
Adjunct in epilepsy
Anxiety
CD4-1
Clonazepam
Benzodiazepine All forms of epilepsy Myoclonus Panic disorder resistant to antidepressant CD4-1
Thiopental
Barbiturate antiepileptic
Status epilipticus
Induction of anaesthesia
Reduction of raised intracranial pressure
Lorazepam
Benzodiazepine Anxiety (and associated insomnia) Acute panic attacks Conscious sedation Premeditation Status epilipticus Febrile convulsions CD4-1
Midazolam
Benzodiazepine Status epilipticus Febrile convulsions Conscious sedation Premeditation Confusion and restlessness in palliative care Convulsions in palliative care CD3
Buspirone
Serotonin receptor agonist antidepressant
Anxiety
Alprazolam
Benzodiazepine
Anxiety
CD4-1
Chlordiazepoxide
Benzodiazepine
Anxiety
Alcohol withdrawal
CD4-1
Diazepam
Benzodiazepine Muscle spasm Tetanus Anxiety (and associated insomnia} Panic attacks Alcohol withdrawal Drug induced dystonic reactions Conscious sedation Status epilipticus Febrile convulsions Dyspnoea associated eith anxiety in palliative care CD4-1
Meprobamate
Non benzodiazepine hypnotic
Anxiety
CD3
Atomoxetine
Centrally acting sympathomimetics
ADHD
Methylphenidate
Centrally acting sympathomimetics
ADHD
Narcolepsy
CD2
Dexamfetamine
Centrally acting sympathomimetics
Narcolepsy
Refractory ADHD
CD2
Lis dexamfetamine
Centrally acting sympathomimetics
ADHD
CD2
Guanfacine
Alpha adrenoreceptor agonist (sympathomimetics)
ADHD when stimulants unsuitable
Asenapine
Second generation antipsychotic
Moderate to severe manic episodes (bipolar)
Lithium
Antipsychotic Mania Bipolar Recurrent depression Aggressive or self harming behaviour
Agomelatine
Melatonin receptor agonist (antidepressant)
Major depression
Isocarboxazid
Monoamine oxidase A and B inhibitor (antidepressant)
Depressive illness
Phenelzine
Monoamine oxidase A and B inhibitor (antidepressant)
Depressive illness
Moclobemide
Monoamine oxidase A inhibitor (antidepressant)
Depressive illness
Social anxiety disorder
Reboxetine
Noradrenaline reuptake inhibitor
Major depression
Citalopram
Serotonin reuptake inhibitor (antidepressant)
Depressive illness
Panic disorder
Fluoxetine
Serotonin reuptake inhibitor (antidepressant) Major depression Bulimia nervosa OCD Menopausal symptoms in breast cancer
Paroxetine
Serotonin reuptake inhibitor (antidepressant) Major depression Social anxiety disorder PTSD OCD Generalised anxiety disorder Panic disorder Menopausal symptoms in breast cancer
Sertraline
Serotonin reuptake inhibitor (antidepressant) Depressive illness OCD Panic disorder PTSD Social anxiety disorder
Duloxetine
Serotonin and noradrenaline reuptake inhibitor Major depressive disorder Generalised anxiety disorder Diabetic neuropathy Stress urinary incontinence
Venlafaxine
Serotonin and noradrenaline reuptake inhibitor Major depression Generalised anxiety disorder Social anxiety disorder Menopausal symptoms in breast cancer
Trazadone
Serotonin uptake inhibitor
Depressive illness
Anxiety
Mianserin
Tetracyclic antidepressant
Depressive illness
Mirtazepine
Tetracyclic antidepressant
Major depression
Amitriptyline
Tricyclic antidepressant Abdominal pain or discomfort Major depressive disorder Neuropathic pain Migraine prophylaxis Chronic tension headache prophylaxis
Clomipramine
Tricyclic antidepressant
Depressive illness
Phobic and obsessional States
Adjunct in cataplexy with Narcolepsy
Dosulepin
Tricyclic antidepressant
Depressive illness
Doxepin
Tricyclic antidepressant
Depressive illness
Pruritis in eczema (cream)
Imipramine
Tricyclic antidepressant
Depressive illness
Nocturnal enuresis
Nortriptyline
Tricyclic antidepressant
Depressive illness
Neuropathic pain
Tryptophan
Antidepressant
Treatment resistant depression
Vortioxetine
Antidepressant
Major depression
Chlorpromazine
First generation antipsychotic Schizophrenia and other psychoses Mania Severe anxiety Intractable hiccup Nausea and vomiting in terminal illness
Flupentixol
First generation antipsychotic
Schizophrenia and other psychoses
Depression
Haloperidol
First generation antipsychotic Nausea and vomiting (incl palliative) Schizophrenia Psychoses Mania/hypomania Organic brain damage Agitation and restlessness in the elderly/palliative Tourettes, tics, intractable hiccup
Loxapine
First generation antipsychotic
Rapid control of mild to moderate agitation (Schizophrenia/bipolar)
Pericyazine
First generation antipsychotic
Schizophrenia, psychoses
Anxiety, psychomotor agitation and violent behaviour
Perphenazine
First generation antipsychotic
Schizophrenia and other psychoses
Mania
Severe nusea and vomiting
Pimozide
First generation antipsychotic
Schizophrenia
Monosymotomatic hypochondriac psychosis
Paranoid psychosis
Prochlorperazine
First generation antipsychotic Schizophrenia and other psychoses Mania Severe anxiety Acute nausea and vomiting (and prevention) Labyrinthine disorder
Sulpride
First generation antipsychotic
Schizophrenia (Higher maximum with predominantly positive symptoms)
Trifluoperazine
First generation antipsychotic Schizophrenia and other psychoses Psychomotor agitation and violence Severe anxiety Severe nausea and vomiting
Zuclopenthixol
First generation antipsychotic
Schizophrenia and other psychoses
Amisulpride
Second generation antipsychotic
Acute psychotic episode of schizophrenia and the disorder with predominantly negative symptoms
Aripiprazole
Second generation antipsychotic
Maintenance of schizophrenia, mania
Agitation and disturbed behaviour
Clozapine
Second generation antipsychotic
Resistant Schizophrenia
Psychoses in Parkinsons
Lurasidone
Second generation antipsychotic
Schizophrenia
Olanzapine
Second generation antipsychotic Schizophrenia Mania Bipolar Agitation and disturbed behaviour
Quetiapine
Second generation antipsychotic
Schizophrenia
Treatment of mania/depression in bipolar
Major depression
Rispeidone
Second generation antipsychotic
Schizophrenia and other psychoses
Mania
Aggression in alzheimer’s
Promazine
First generation antipsychotic
Psychomotor agitation
Agitation and restlessness in elderly
Piracetam
CNS stimulant
Adjunct in cortical Myoclonus
Tetrabenazine
Monoamine depleting drug
Movement disorders from Huntington and neurological conditions
Moderate to severe tardive dyskinesia
Botulinum toxin
Muscle relaxant Focal spasticity Prophylaxis of headaches Ankle disability from stroke Crows feet
(B) just spasmodic totticollis (cervical dystonia)
Orphenadrine
Antimuscarinic
Parkinsonism
Drug induced extrapyrimidal symptoms (not tardive dyskinesia)
Procyclidine
Antimuscarinic
Parkinsonism
Extrapyrimidal symptoms (not tardive dyskinesia)
Acute dystonia
Entacapone
COMT inhibitor
Adjunct to cobeneldopa or cocareldopa in Parkinsons with end of dose motor fluctuations
Tolcapone
COMT inhibitor
Adjunct to cobeneldopa or cocareldopa in Parkinsons with end of dose motor fluctuations if another COMT inappropriate
Co-beneldopa or co-careldopa
Dopamine precursor
Parkinsons disease
Amantadine
Dopamine receptor agonist
Parkinsons disease
Post herpetic neuralgia
Influenza a prophylaxis and treatment
Apomorphine
Dopamine receptor agonist
Refractory motor fluctuations in parkinsons (off episodes) inadequately controlled by other dopaminergics
Bromocriptine
Dopamine receptor agonist Prevention of lactation Hypogonadism Galactorrhoea Infertility Acromegaly Prolactinoma Parkinsons
Cabergoline
Ergot derived Dopamine receptor agonist
Prevention of lactation
Hyperprolactinaemia
Parkinsons (others inappropriate)
Pergolide
Ergot derived Dopamine receptor agonist
Parkinsons
Pramipexole
Dopamine receptor agonist
Parkinsons
Restless leg syndrome
Ropinorole
Dopamine receptor agonist
Parkinsons
Restless leg syndrome
Rotigotine
Dopamine receptor agonist
Parkinsons
Restless leg syndrome
Rasagiline
MAOB inhibitor
Parkinsons for end of dose fluctuations
Selegiline
MAOB inhibitor
Parkinsons to reduce end of dose deterioration
Symptomatic parkinsonism
Cyclizine
Antihistamine antiemetic
Nausea, vomiting, vertigo, motion sickness, labyrinthine disorder
Different doses when associated with vestibular disorder, palliative care
Nabilone
Cannabinoid antiemetic
Nausea and vomiting caused by cytotoxic chemotherapy, unresponsive to conventional
Domperidone
Dopamine receptor antagonist antiemetic
Relief of nausea and vomiting
Gastro intestinal pain in palliative care
Metoclopramide
Dopamine receptor antagonist antiemetic
Nausea and vomiting including that associated with acute migraine.
Delayed chemo induced nausea and vomiting
Radiotherapy induced nausea and vomiting
Prevention of post op nausea and vomiting
Hiccup/nausea and vomiting in palliative care
Aprepitant
NK receptor antagonist antiemetic
Adjunct for nausea and vomiting associated with moderately and highly emetohenic chemotherapy
Fosaprepitant
NK receptor antagonist
Adjunct to dexamethasone and serotonin antagonist to prevent nausea and vomiting associated with moderately and highly emetogenic chemotherapy
Granisetron
Serotonin receptor antagonists
Nausea and vomiting induced by cytotoxic chemotherapy
Prevention/treatment of postoperative nausea and vomiting
Ondansetron
Serotonin receptor antagonists
Moderately and severely (Higher dose) emetogenic chemotherapy or Radiotherapy
Prevention and treatment of postoperative nausea and vomiting
Cinnarizine
Sedating antihistamine
Vertigo, tinnitus nausea and vomiting in minieres
Motion sickness
Promethazine
Sedating antihistamine
Nausea, vomiting, labyrinthine disorder
Motion sickness prevention/treatment (works longer as teoclate)
Hyoscine hydrobromide
Antimuscarinic Motion sickness Hypersalivation with clozapine Excessive respiratory secretion Bowel colic in palliative care Premeditation
Levomepromazine
First generation antipsychotics
Pain in palliative care (reserved for distressed with severe pain)
Restlessness and confusion in palliative care
Nausea and vomiting in palliative care
Schizophrenia
Betahistine
Histamine analogue
Vertigo tinnitus hearing loss associated with menieres
Paracetamol
Non opioid analgesic Mild to moderate pain and pyrexia 0.5-1g every 4 to 6 hours. Max 4g. (15mg/kg up to 50kg) 2/4months (post immunisation) =60mg at vaccination, after 4-6hs (2 doses) Every 4-6h; 3-5m = 60mg 6m-1y = 120mg 2-3y = 180mg 4-5y = 240mg 6-7y = 240 - 250mg 8-9y = 360 - 375mg 10 - 11 = 480 - 500mg 12 - 15 = 480 - 750mg
Max 3g if ris of Hepatitoxicity
Nefopam
Non opioid centrally acting analgesic
Moderate pain
Buprenorohine
Opioid analgesic. Moderate to severe pain Premeditation Intra operative analgesia Adjunct in opioid dependance Chronic cancer pain CD3
Codeine
Opioid analgesic Acute diarrhoea Mild to moderate pain Dry or painful cough CD5