Class: Exam 2 Reactive Tumors Flashcards
Most common “tumor” of the oral cavity
fibroma
What is a Fibroma
A reactive hyperplasia of fibrous connective tissue in response to local irritation or trauma
Where is the most common location for a fibroma?
the buccal mucosa along the bite line
*However, it occurs almost anywhere…
Name the clinical features of Fibromas
Usually sessile (immobile), Smooth surfaced, normal color, and Asymptomatic
Treatment of irritation fibroma
Treated by conservative surgical excision
Define Giant Cell Fibroma
A “papillary” fibrous tumor of connective tissue comparable to an irritation fibroma but not associated with chronic irritation.
What other lesion may a giant cell fibroma be clinically mistaken for?
A papilloma
What is the hallmark of a giant cell fibroma
Presence of numerous large, stellate fibroblasts within the superficial connective tissue.
Also, often bi or trinucleated fibroblasts.
Other than the major hallmark, what other feature/features distinguish giant cell fibromas from irritation fibromas
The lesion usually occurs a a younger age, usually diagnosed during the first 3 years of life. (a.ka. –>more in children)
Clinical features of giant cell fibroma?
Asymptomatic
Sessile (immobile) or pedunculate nodule
Less than 1 cm in size
Surface often appears papillary
What is the major location in which giant cell fibroma’s are found
Approx. 50% cases found on gingiva
Tongue also common site
Define Peripheral Ossifying Fibroma
Reactive fibroblastic lesion of PDL
Describe the location/s where peripheral ossifying fibromas may be found
Exclusively on the gingiva
Describe the clinical features of a Peripheral Ossifying fibroma
Asymptomatic Sessile or Pedunculated mass (usually emanates from interdental papilla) Color: red to pink Sometimes ulcerated Most are less than 2 cm in size
What age is common for peripheral ossifying fibroma
1-3 decades
predominantly a lesion of teenagers and young adults with peak prevalence between 10-19 yrs.
Histologic features of peripheral ossifying fibromas
Cellular fibroblastic lesion with bone and/or cementum and/or dystrophic calcification
Treatment for peripheral ossifying fibromas
Excision including superficial PDL
Submission of specimen for exam (biopsy)
Recurrence rate of 15-20% –> Highest of any reactive gingival lesions
Define Inflammatory Fibrous Hyperplasia (Epulis Fissuratum)
Reactive folds of hyper plastic fibrous connective tissue along border of ill-fitting, over extended denture
Histologic features of Epulis Fissuratum
Fibrous hyperplasia +- inflammation
Treatment of Epulis Fissuratum
Excision and remake/reline denture
Define Inflammatory Papillary Hyperplasia (Papillomatosis)
Reactive tissue growth of hyper plastic palatal mucosa usually developing beneath a denture.
Histologic features of Inflammatory Papillary Hyperplasia
Papillary Hyperplasia +- Inflammation +- Pseudoepitheliomatous Hyperplasia (PEH)
Treatment options for Inflammatory Papillary Hyperplasia
Early lesions - removal of denture may allow erythema and edema to subside and tissues may resume normal appearance
Advanced lesions - excision and remake/reline denture.
Define Peripheral Giant Cell Granuloma
Tumor of well vascularized fibrous connective tissue containing numerous multinucleated giant cells