CLASS COTYLODA (Pseudophyllidea): Family Diphyllobothriidae Flashcards
Diphyllobothrium latum CN
“broad fish tapeworm of man”
Family Diphylobothridae genera
Diphylobothrium
Spirometra
Hosts of Diphyllobothrium latum “broad fish tapeworm of man”
fish-eating mammalsman, dogs, cats
Its hosts are fish-eating mammalsman, dogs, cats
Diphyllobothrium latum
Site of Diphyllobothrium latum
small intestine
1st IH of Diphyllobothrium latum
copepods (Diaptomus vulgaris, Cyclops strenuus)
Diaptomus vulgaris CN
Cray fish
2nd IH of Diphyllobothrium latum
freshwater fish (trout, pike, salmon, perch)
Morphology of Diphyllobothrium latum
- Could be as long as 20 meters in length with up to 3000 segments
- largest tapeworm of man
- yellowish grey in color with dark central ventral markings caused by the uterus
- With 2 muscular longitudinal grooves (bothria) at the spoon-shaped scolex
- Embryophore bears a cilia, once the eggs are hatched the larva is motile (coracidium)
- Bilobed ovary is central
- Roseate-shaped uterus is central and opens ventrally
- Eggs are operculated, light brown, with round ends
Could be as long as 20 meters in length with up to 3000 segments
Diphyllobothrium latum
largest tapeworm of man
Diphyllobothrium latum
Eggs are operculated, light brown, with round ends
Diphyllobothrium latum
Life Cycle of Diphyllobothrium latum
- eggs are voided out with the feces
- develops into 1st stage larva (coracidium) in two weeks
- coracidium swims in water and become ingested by 1st i.h. within 12 hours
- procercoid in 2-3 weeks
- 2nd i.h. eat infected copepods
- plerocercoid develops in the muscle tissue of fish
- ingestion of raw or partially cooked fish with plerocercoid
- eggs appear in the feces 5-6 weeks post-infection
Essentially a parasite of humans because it produces few fertile eggs in other hosts
Diphyllobothrium latum
Diphyllobothrium latum competes for this vitamin uptake
B12
Treatment for Diphyllobothrium latum
Praziquantel 25 mg/kg
Niclosamide
Quinacrine
Spirometra erinacei CN
Zipper worm disease
Spirometra spp. causes what disease?
Spirometrosis
Morphology of Spirometra erinacei
- Adults measure 25-75 cm
- Mature proglottids often separate along the longitudinal axis for a short distance
- Egg is yellowish brown, asymmetric
- The second larval stage (plerocercoid) is specifically referred to as sparganum
the tapeworm appears to “unzip”, hence the name of______
zipper tapeworm
The second larval stage (plerocercoid) is specifically referred to as ______
sparganum
sparganum causes what disease in human?
sparganosis
Most common pseudophyllidean tapeworm in the Philippines
Spirometra erinacei
It is prevalent in Japan, Korea, China, Vietnam and sporadically in other continents
Sparganosis
Difference between Diphyllobothrium and Spirometra species
Diphyllobothrium spp.
Eggs: Ovoid, with zygote
Uterine coils: Roseate
Cirrus and vaginal opening: Common
First intermediate host: Diaptomus
Second intermediate host: Fish
Final host: Man, carnivores
Length: 20 meters (3000 segments)
Eng color: light brown
Spirometra spp.
Eggs: asymmetric
Uterine coils: Spiral
Cirrus and vaginal opening: Separate
First intermediate host: Cyclops
Second intermediate host: Frog, reptile, mammal, bird
Final host: carnivores
Length: 15-75 cm
Eng color: yellow brown
1ST IH of Diphyllobothrium spp.
Diaptomus
1ST IH of Spirometra spp.
Cyclops
2nd IH of Diphyllobothrium spp.
Fish
2nd IH of Spirometra spp.
Frog, reptile, mammal, bird
Final host of Diphyllobothrium spp.
Man, carnivores
Final host Spirometra spp.
carnivores
Adults are generally harmless and may cause intermittent diarrhea
Spirometra erinacei
Infective stage of Spirometra erinacei
Plerocercoid (sparganum)
This disease in man is caused by spargana characterized by the presence of larvae in muscles and tissues
Sparganosis
Treatment for Sparganosis
- Surgical removal of plerocercoid or sparganum in humans * Arecoline Hydrobromide (areca nut) 1-2 mg/kg bw
- Dichlorfen 20 mg/kg
- Quinacrine HCI 15-40 mg/kg
Disease of cyprinid and silurid fish
Ligulosis
1st IH of ligulosis
Cyclops
Caused by plerocercoids of tapeworms Ligula intestinalis and Digramma interrupta in birds
Ligulosis
Causative agents of Ligulosis
Ligula intestinalis (fish) and Digramma interrupta (birds)
Causative agent of ligulosis in birds
Digramma interrupta
Causative agent of ligulosis in fishes
Ligula intestinalis
It causes parasitic castration in fishes
Ligula intestinalis
More pathogenic species under Family Diphyllobothriidae
Genus Diphyllobothrium
Less pathogenic species under Family Diphyllobothriidae
Genus Spirometra
Infective stage of Spirometra
Plerocercoid