Class 8 - Inflammatory & Infectious Diseases pt. 2 Flashcards

1
Q

The bacteria that causes syphilis is called…

A

treponema pallidum

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2
Q

Syphilis sores are called…

A

chancres

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3
Q

The most effective antibiotic for syphilis is…

A

penicillin

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4
Q

Chancres develop ___ weeks after exposure to treponema pallidum

A

1-12

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5
Q

One of the primary S&S of syphilis is…

A

inguinal lymphadenopathy

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6
Q

Second stage syphilis will see what S&S? It occurs when?

A

macular rash
condyloma latum (elevated skin lesions/papules)
hepatitis, other organ inflammation

2 months to 2 years

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7
Q

What are gummas?

A

Granulomatous lesions characterized by a centre of necrotic tissue with a rubbery texture

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8
Q

Gummas can break down to form ___ and are often found in the ___, ___, and ___.

A

ulcers

liver, bones, testes

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9
Q

The tertiary stage of syphilis most notably affects the ___ system

A

cardiovascular

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10
Q

Cardiovascular syphilis/tertiary stage doesn’t occur until at least __ years after initial infection

A

10 years

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11
Q

The two most common CVS manifestations of tertiary syphilis are:

A
  1. aneurysm formation in the ascending aorta

2. gumma of the cardiac valves!!!!

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12
Q

What is tabes dorsalis?

A

symptoms of neurosyphilis where the dorsal column and dorsal root degenerate, there is a loss of sensory nerves resulting in wide-based gait (impaired proprioception) and impaired sensation of pain, temperature, vibration, and areflexia.

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13
Q

Neurosyphilis sees what kind of paresis?

A

‘general paresis of the insane’ d/t damage to cortical brain regions

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14
Q

Bell’s palsy is mot common between the ages of _ and _

A

15 and 45

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15
Q

Two likely culprits behind bell’s palsy (though it’s usually idiopathic) are…

A

reactivated shingles
lyme disease bacteria

acoustic neuromas

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16
Q

What two conditions have an increased risk of bell’s palsy?

A

diabetes mellitus

pregnancy

17
Q

The treatment for bell’s palsy is…

A

high dose corticosteroids for 5 days and lower for 5 more days (ASAP!)

may also be paired with antiviral tx

18
Q

Bell’s palsy has 100% recovery if treated within _ days of onset, and only __ after 4 days

A

3 days

86% after 4 days

19
Q

Vestibular neuritis is most likely caused by…

A

viral infection of the inner ear, or viral infections occurring elsewhere in the body

20
Q

Labyrinthitis is when… what are the symptoms?

A

both branches of the vestibulocochlear nerve are swollen, affecting balance and hearing.

symptoms are same as vestibular neuritis + tinnitus and/or hearing loss

21
Q

S&S of vestibular neuritis include…

A
nystagmus
sudden, severe vertigo
dizziness
balance difficulties
nausea, vomiting
difficulties concentrating