Class 8 - Inflammatory & Infectious Diseases pt. 2 Flashcards
The bacteria that causes syphilis is called…
treponema pallidum
Syphilis sores are called…
chancres
The most effective antibiotic for syphilis is…
penicillin
Chancres develop ___ weeks after exposure to treponema pallidum
1-12
One of the primary S&S of syphilis is…
inguinal lymphadenopathy
Second stage syphilis will see what S&S? It occurs when?
macular rash
condyloma latum (elevated skin lesions/papules)
hepatitis, other organ inflammation
2 months to 2 years
What are gummas?
Granulomatous lesions characterized by a centre of necrotic tissue with a rubbery texture
Gummas can break down to form ___ and are often found in the ___, ___, and ___.
ulcers
liver, bones, testes
The tertiary stage of syphilis most notably affects the ___ system
cardiovascular
Cardiovascular syphilis/tertiary stage doesn’t occur until at least __ years after initial infection
10 years
The two most common CVS manifestations of tertiary syphilis are:
- aneurysm formation in the ascending aorta
2. gumma of the cardiac valves!!!!
What is tabes dorsalis?
symptoms of neurosyphilis where the dorsal column and dorsal root degenerate, there is a loss of sensory nerves resulting in wide-based gait (impaired proprioception) and impaired sensation of pain, temperature, vibration, and areflexia.
Neurosyphilis sees what kind of paresis?
‘general paresis of the insane’ d/t damage to cortical brain regions
Bell’s palsy is mot common between the ages of _ and _
15 and 45
Two likely culprits behind bell’s palsy (though it’s usually idiopathic) are…
reactivated shingles
lyme disease bacteria
acoustic neuromas