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Pharm II Exam 4 > Class > Flashcards

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1
Q

WT allele of Ethanol

A

ALDH2*1 (G1510;Glu487) → proper acetaldehyde metabolism

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2
Q

WT allele of 5-fluorouracil (5FU)

A

DPD*1 (97%of pt pop) homozygous for WT ‘G’ allele found in intron

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3
Q

WT allele of Codeine

A

CYP2D6*1 proper conversion of codeine → good efficacy

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4
Q

WT allele of Warfarin

A

CYP2C9*1

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5
Q

Albendazole

A

Anti-Helminthic

Benzimidazole

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6
Q

Mebendazole

A

Anti-Helminthic

Benzimidazole

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7
Q

Ivermectin

A

Anti-Helminthic

Avermectin

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8
Q

Pyrantel Pamoate

A

Anti-Helminthic

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9
Q

Diethylcarbamazine

A

Anti-Helminthic

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10
Q

Praziquantal

A

Anti-Helminthic

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11
Q

Artemether

A

Anti-Malaria

Artemisinins

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12
Q

Artesunate

A

Anti-Malaria

Artemisinins

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13
Q

ACT with Lumefantrine

Coartem

A

Anti-Malaria

Artemisinins

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14
Q

Chloroquine Phosphate

A

Anti-Malaria

Quinolines & Related compounds

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15
Q

Quinne Sulfate

A

Anti-Malaria

Quinolines & Related compounds

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16
Q

Primaquine

A

Anti-Malaria

Quinolines & Related compounds

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17
Q

Atovaquone

A

Anti-Malaria

Adjunctive with Quinolones

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18
Q

Proguanil

A

Anti-Malaria

Adjunctive with Quinolones

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19
Q

Clindamycin

A

Anti-Malaria

Adjunctive with Quinolones

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20
Q

Isoniazid (INH)

A

Anti-TB

Cell Wall Inhibitors

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21
Q

Pyrazinamide

A

Anti-TB

Cell Wall Inhibitors

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22
Q

Ethambutol

A

Anti-TB

Cell Wall Inhibitors

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23
Q

Rifampin

A

Anti-TB

Rifamycins

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24
Q

Streptomycin

A

Anti-TB

Aminoglycosides

25
Q

Amikacin

A

Anti-TB

Aminoglycosides

26
Q

Bedaquiline

A

Anti-TB

MDR TB

27
Q

Fluroquinolines

A

Anti-TB

Levofloxacin

28
Q

Amhotericin B

A

Antifungals

Polyenes

29
Q

Nystatin

A

Antifungals

Polyenes

30
Q

Fluconazole

A

Antifungals

Azoles

31
Q

Itraconazole

A

Antifungals

Azoles

32
Q

Voriconazole

A

Antifungals

Azoles

33
Q

Caspofungin

A

Antifungals

Echocandins “fungins”

34
Q

Griseofulvin

A

Antifungals

Mitotic inhibitor

35
Q

Terbinafine

Lamisil

A

Antifungals

fungal enzyme inhibitor

36
Q

Flucytosine

A

Antifungals

Anti-metabolite

37
Q

Cobicistat

A

CYP3A4 inhibitor

38
Q

Acyclovir

A

Anti-Herpes Agents

39
Q

Ganciclovir

A

Anti-CytomMgaloVirus Agents

40
Q

Valganciclovir

A

Anti-CytomMgaloVirus Agents

41
Q

Foscarnet

A

Anti-CytomMgaloVirus Agents

42
Q

Amantidine

A

Anti-Influenza Agents

43
Q

Oseltamivir (Tamiflu)

A

Anti-Influenza Agents

44
Q

Zanamivir (Relenza)

A

Anti-Influenza Agents

45
Q

Abacavir

A

Anti-Retroviral Agents

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

46
Q

Lamivudine

A

Anti-Retroviral Agents

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

47
Q

Emtricitibine

A

Anti-Retroviral Agents

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

48
Q

Tenofovir (AF/DF)

A

Anti-Retroviral Agents

Nucleotide Reverse Transcriptase Inhibitors

49
Q

Efavirenz

A

Anti-Retroviral Agents

Non-nucleoside Reverse Transcriptase Inhibitors

50
Q

Ritonavir

A

Anti-Retroviral Agents

HIV protease Inhibitors

51
Q

Darunavir

A

Anti-Retroviral Agents

HIV protease Inhibitors

52
Q

Atazanavir

A

Anti-Retroviral Agents

HIV protease Inhibitors

53
Q

Lopinavir

A

Anti-Retroviral Agents

HIV protease Inhibitors

54
Q

Enfuvirtide

A

Anti-Retroviral Agents

Fusion, entry and integration inhibitors

55
Q

Maraviroc

A

Anti-Retroviral Agents

Fusion, entry and integration inhibitors

56
Q

Doutegravir

A

Anti-Retroviral Agents

Integrase Strand Transfer Inhibitors (INSTIs)

57
Q

Raltegravir

A

Anti-Retroviral Agents

Integrase Strand Transfer Inhibitors (INSTIs)

58
Q

Elvitegravir

A

Anti-Retroviral Agents

Integrase Strand Transfer Inhibitors (INSTIs)

Pharm II Exam 4 (7 decks)

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