Class 5: Mental Health Flashcards
Common outcomes for schizophrenia
Reduced risk of harm to self or others
Refrains from attending to and responding to delusions and hallucinations
Increased self-care, medication adherence
Asks for validation of reality, exhibits reality-based thinking
Nursing interventions for schizophrenia
-Self-care, milieu, & group therapy
Promoting self-care + nutrition
Antipsychotics cause weight gain leading to the onset or worsening of diabetes and metabolic syndrome
Self-care in schizophrenia + attire
Clean & weather appropriate clothing
Purpose of milieu therapy
-Decrease stimuli, protection from stressors and structured activities
-Monitor for signs of aggression
Structured activities provide…
Distraction from delusions and hallucinations
Signs of aggression
Externally responding to delusions and hallucinations
Purpose of group therapy in schizophrenia
-Increase social skills, modify unacceptable behavior
-Participate in constructive leisure activities
-Provide external support and opportunities to practice new skills
Antipsychotics: General information
-Known as neuroleptics
-Highly lipid soluble
Typical antipsychotics
-1st gen/conventional antipyschotics
-CHFPFZ
-Chloropromazine
-Haloperidol
-Fluphenazine
-Primozide
-Flupenthixol
-Zuclopenthixol
Typical antipyschotic MOA
Block D2 receptors (dopamine receptors that control synthesis, release & reuptake)
Typical antipsychotic indications
-Treat positive NOT negative symptoms
-Psychosis, Schizophrenia, Bipolar, Aggression/Agitation
Other information about typical antipsychotics
-2nd line tx
-Used for depot injection (long acting, 2 weeks)
-Less weight gain, decreased incidence of metabolic syndrome
Typical antipsychotic interactions
-CNS depressants (additive, increased sedative effect)
-Stimulant (competes, decreased effectiveness)
CNS adverse effects + typical antipyschotics
Sedation & reduced seizure threshold
Extra pyramidal symptoms + typical antipsychotics
Dystonia, akathisia, pseudo parkinsonism, tardive dyskinesia
Neuroleptic malignant syndrome + typical antipsychotics
-Muscle rigidity
-Increased temperature, HR & CK, aBP & mental status
Agranulocytosis + typical antipsychotics
Decreased neutrophils
Typical antipsychotics CV adverse events
Postural hypotension, tachycardia, non-specific ECG changes, arrhythmia
Typical antipsychotic anticholinergic adverse events
Dry mouth, blurred vision, constipation & urinary retention
Typical antipsychotic adverse events + endocrine/sexual side effects
-Increase prolactin
-Decreased sexual drive, ED, retrograde ejaculation
Typical antipsychotic GI adverse events
Constipation/diarrhea
Atypical antipsychotic medications
-2nd gen/unoconventional antipsychotics
-“pines”, “dones”, LAZCORQ
-Lurasidone, ziprasidone, risperidone
-Quetiapine, clozapine, olanzapine,
-Aripiprazole
Atypical antipsychotic MOA
-ACHS
-Blocks dopamine receptors D1 – D5 (serotonergic, alpha adrenergic, histamine, and cholinergic receptors)
-Preferential binding in the limbic area vs. the striatum area of the brain; reduces EPS
Atypical antipsychotic indications
-Treat positive & negative symptoms of schizophrenia
-TX of bipolar disorder, and for aggression/agitation
Atypical antipsychotic: Other information
-Less EPS & prolactin elevation, lower risk of TD
-Improve cognition
-Considered 1st Line Treatment
Atypical antipsychotic interactions
CNS depressants & stimulants
Atypical antipsychotic adverse reactions
-Headache, nausea, sedation, fatigue
-Anticholinergic effects
-Weight gain, edema, dyslipidemia, hyperglycemia, hyperthermia
-HTN, hypotension, tachycardia, increased prolactin, prolonged Q-T
-EPS, NMS