Class 3: How many Synthetic Chemicals are there Flashcards
(28 cards)
Synthetic chemicals
- production has risen
- huge increase after 1945 due to plastic
Toxicants
Are bioactive synthetic chemicals
CAS
Contain
- unique organic and inorganic chemicals
- coordination compounds minerals, polymers and salts
Exponential increase
In the numbers of synthetic industrial chemicals
New drug increase
Pharmaceutical preparations, tissue - implantable materials and medical devices
Litigation
Principally as a consequence of occupational-related illness, unrecognized or poorly documented product safety concerns( including drugs) and environmental harm (ex. Oil spill)
Enhance public awareness
Of potential adverse effects of chemicals on humans, animals and the environment
Mandatory testing
And regulations of chemicals used commercially, domestically and medically
The exposome
Represents all exposures, of a life time
-including from diets, lifestyle
Endogenous source
Chemical inside body( end of life)
Genome era
Measured all genes can all disease
External exposome -in practice
- heart rate monitors
- Sensors of air pollutants
- diet captured on smart phones
- drinking water contaminants
Internal exposome
Exposure to infections
- Urine:pollutants, drug, metabolites
- stress
- behavior and life style
- diet
- radiation
Coffee
Average cup, contains about 8,200 different natural chemicals
Human genome survey
Completed June 26, 2000
Exposimeter
Has pump sucks air at 1.15 captures chemicals
Toxins
Are natural bio active compounds
Chemicals Found in nature
Cause biochemical or physiological actions in organisms
Phytotins( are natural)
Bio active chemicals from plants
-represent 1 of 2 main source of drugs( pharmaceutical) on the market today
Mycotoxins
Bio active chemicals from mold and fungi
-represent 1 of 2 main source of drugs( pharmaceutical) on the market today
Toxic
An adjective that can capture adverse properties of natural and synthetically substance
Oxidants from oxygen
- o2-( superoxide anion )
- pyroxylin radical
- hydrogen peroxide
- hydroxyl radical
Free radical
Reactive chemicals missing electron
-“electron search”
Effect of oxidant
Telomere shortening
-chromosomes lose telomeres over time