Class 2 Asepsis & Infection Control Flashcards
Infection
a disease that results from a pathogen in or on the body
healthcare associated infections (HAI)
infections that develop during the course of treatment for other conditions; most can be preventable!!
Most common (top offenders) HAI
urinary tract infections
surgical site infections
bloodstream infections
pneumonia
Nosocomial
something that originated or occurred inside a hospital setting
Bloodborne Pathogens
infectious microorganisms in the blood/body secretions that can cause disease in humans
Iatrogenic?
something that wasn’t supposed to happen
Preventing health care associated infections
HAI in USA annually:
-2 million infections
-99,000 deaths
-$30.5 billion dollars in associated costs
Medicare/medicaid no pay list (10 conditions)..hospitals will not be paid for any costs related to (3)
-CAUTI: catheter associated urinary tract infections
-vascular catheter related infections
-surgical site infections
Factors predisposing patients to nosocomial infections
-being in hospital
-antibiotic-resistant organisms developed in hospitals (MRSA, VRSA, VRE)
-poor compliance with hand washing, standard precautions and transmission based precautions
Infectious agents
-bacterial: most significant and most prevalent in hospital settings
-virus: smallest of all microorganisms
-fungi: plant like organisms present in air, soil, and water (no flowers in ICU)
Components of the infection cycle
-infectious agent (pathogen-not all infectious)
-reservoir (where do live?)
-portal of exit
-means of transmission (how do travel? contact, airborne, droplet)
-portal of entry
-susceptible host
Possible reservoirs of micro-organisms
-other humans (TB)
-animals, insects (west nile, zika)
-soil (tetanus)
-food, water, milk (listeria, E. coli, salmonella)
-inanimate objects
common portals of exit/entry
pathogens generally enter and exit via the same portals
-respiratory
-gastrointestinal
-genitourinary tracts
-breaks in skin (intact skin is body’s 1st line of defense**)
-blood and body fluids (everything but sweat!)
How to break the chain of infection
-infectious agent–>reservoir (hand hygiene)
-reservoir–>portal of exit from reservoir (transmission-based precautions)
-portal of exit–>means of transmission (dry intact dressing/hand hygiene)
-means of transmission–>portals of entry (hand hygiene)
-portals of entry–>susceptible host (hand hygiene)
-susceptible host–>infectious agent (immunizations)
Factors affection host susceptibility
-intact skin & mucous membranes: this is the bodies first line of defense against infection**
-body’s white blood cells: low counts allow pathogens to multiply
-patients with splenectomy (filters bacteria)
-age: neonates and older adults are more susceptible to infection
-immunization, natural or acquired
-fatigue: decreased immune response
-nutritional status: poor nutritional status inhibits our ability to fight infection
-drug therapies: many drugs suppress our immune system response (steroids, chemo)
-stress: increased stress will adversely affect normal defense mechanisms
-use of invasive or indwelling medical devices:provides portal of entry for pathogens (IV)
Stages of infection
incubation period
prodromal stage
full stage of illness
convalescent period
incubation period
organisms growing and multiplying
-not feeling sick; no symptoms
-flu=1-4 days; Hep B=1-6 maths
prodromal stage
person is most infectious, vague and nonspecific signs of disease
-“I don’t feel well”
full stage of illness
presence of specific signs and symptoms of disease
convalescent period
recovery from the infection
-start to feel better
Manifestations of the presence of an infection
-local infection
-systemic infection
local infection
will see:
-swelling, heat at site, redness, pain
-loss of function
-purulent drainage
systemic infection
will see:
-elevated temperature (not in the elderly! their temp will be normal, but their level of consciousness will deteriorate)
-increased pulse and respiratory rate (increased metabolism)
-enlarged lymph nodes
-lethargy, anorexia (loss of appetite)
Laboratory data indicating infection CBC with differential (diff)
-elevated white blood cell count >10,000/mm3
-increase in specific types of white blood cells
-neutrophils(bands-immature, left shift):acute bacterial infections (should be less than 10%); generate fever response
-lymphocytes chronic bacterial (TB) and viral infections; important in synthesis of immunoglobulins
-eosinophil elevated in parasitic infection, fungus (cocci), allergic reaction; increase in response to allergic & parasitic conditions when an antigen-antibody response occurs
-C-reactive protein is non-specific and indicates inflammation (presence of pathogen in urine, blood, sputum, or drainage cultures)
-diagnostic tests such as CXR, lumbar puncture
hospital privacy curtains
are dirty!
-in study 92% of curtains showed contamination in 1 week (30 curtains)
-8 curtains yielded VRE at multiple time points
-privacy curtains are rapidly contaminated with potentially pathogenic bacteria
Paper study
4 pathogens were prepared on paper
-e. coli
-staph
-pseudomonas
-enterococcus
still stable on paper for up to 72 hours and still cultured after 7 days
**don’t bring paper in isolation room
MDRO
multi drug resistant organisms