Class 11 CADTH

Question 1

CADTH delivers 4?
and does 5

CADTH is a national organization located in all provinces and territories (except Ontario and Quebec)

Answer 1

Evidence Analysis, Advice, Recommendations

• Medical Devices and related Equipment Purchases
• Pharmacologic Agents
• Surgical Procedures
• Non-surgical Procedures or Approaches to Treatment
• Vaccines and Other Preventive Interventions

Question 2

Products and Services
When to use

Drug Reimbursement Recommendations 2
Health Technology Management
Other Products and Services 3
Knowledge Mobilization and Liaison Officers 4

Answer 2

Drug Reimbursement Recommendations

• CADTH Common Drug Review (CDR)
• CADTH Pan-Canadian Oncology Drug Review (PCODR)

Health Technology Management

• Rapid Response Service
• Health Technology Assessment
• Optimal Use

Other Products and Services

• Environmental Scanning
• Horizon Scanning
• CADTH Scientific Advice Program

Knowledge Mobilization and Liaison Officers

• Informal scans across Canada for information or contacts
• Educational workshops
• Policy development
• Tool creation

Question 3

Why use CADTH 6

Answer 3

• Evidence gathering
• Policy and Procedure writing
• Purchasing a new piece of equipment
• Educational opportunities
• Modifying practice
• *(Time)

Question 4

Evidence-informed decision-making evolved from what, and reflects what

Made up of 5 things

assumes what 2

Answer 4

EIDM has evolved from what we formally knew as “evidence based decision making”. It reflects a more thoughtful and contemplative approach of what best available scientific evidence “fits” with local environment and clinical experience for particular decision-making situations

• Clinical Experience
• Patient perspectives and values
• Best available scientific evidence
• Available resources
• Local issues, context
• assumes an understanding of available credible work, factoring in practical considerations that may include resources, funding, current unique practice needs, and patient-specific preferences
• Assumes that in some areas of health care, evidence may be lacking, sparse, or contradictory and that more local “common sense” perspectives may prevail

Question 5

6 Steps in EIDM

Answer 5

Ask:
Use info from your requestor to prepare a clinical question in a specific way so you have all the info (PICOTS)

Anticipate:
Plan an online search strategy to locate credible evidence

Acquire:
Find the best evidence that helps to answer the question

Appraise:
Decide if the particular study is good enough to use (3R’s)

Adapt:
Use parts or all of quality information to list key “results” and build a response that could work in your requestor’s specific clinical setting

Apply / Report:
Integrate the evidence and write about it

Question 6

1. ASK
   - What is the PICOTS Approach
   - 5 Steps to proper evidence based decision

Answer 6

P = Patient/ POP.
I= Intervention
C = Comparison/Context
T= Timeframe
S = Study Type

1. Formulate a clear, focused clinical question (PICO model) – this is the first step of any evidence based process – questions of patient care, formulary review, literature review, clinical guidelines
2. Search the literature for the best external evidence
3. Critically appraise the evidence for its validity and usefulness
4. Implement the useful evidence in clinical practice
5. Evaluate the results

Question 7

2. Anticipate

Google Cautions 6

Look in Grey Literature

• What does it include
• What has CADTH developed
• It does what 3

If you cant find anything else on CINHAL where do you go

Answer 7

• Google is a non-filtered source of information
• Companies/Group may “purchase” space for higher prioritization of their item
• Some Google “hits” reflect subtle (and not-so-subtle) advertisement for services, products, marketing initiatives, surveys or tallies, or other)
• Google tracks your search patterns within its engine and prioritizes items within your search lists that a pre-set algorithm thinks you want to see
• Many sources of evidence do not contain references, dates of publication, etc
• Google pulls “info” from peer-reviewed and non-peer-reviewed journals and doesn’t tell you the difference!
• Grey literature includes reports and government information that are not published commercially and that are inaccessible via bibliographic databases
• CADTH developed a Grey Literature Checklist to provide guidance when grey literature searching.
• The checklist is used to:
• -Ensure the retrieval of all relevant HTA, government, and evidence-based agency reports that may not be indexed in a bibliographic database such as MEDLINE
• -Help document the grey literature search process, thereby increasing transparency and the potential for reproducibility
• -Ensure that grey literature searching is done in a standardized and comprehensive way

CADTH Gray matters