Citric acid cycle, reagents, products enzymes

Question 1

1st step in the citric acid cycle?

1) reactants and products
2) enzymes

Answer 1

Pyruvate to acetyle CoA.

IN: NAD+ + COA
OUT:NADH + H+ CO2

Pyruvate DH complex

Question 2

2nd step of citric acid?

Answer 2

Acetyl- CoA+ Oxaloacetate= citrate

Citrate synthase

h20 and acetyl CoA out.

Question 3

Citrate >?

Answer 3

aconitate
h20 out
aconitase enzyme

Question 4

Aconitate to?

Answer 4

Acontate> Isocitrate

aconitase enzyme

in: h20

Question 5

Isocitrate onwards

Answer 5

-2-oxo-glutarate

Isocitrate DH

IN:NAD+
OUT:NADH + H+ +CO2

Question 6

2-oxo-glutarate onwards

Answer 6

SuccinylCoA formation
2-oxoglutarate DH complex (E3 same as PDHC)

IN: NAD+ + CoA
OUT: NADH + H+ +CO2

Question 7

Succinyl coA to ?

Answer 7

Succinate

enzyme: Succinate thiokinase

IN:ADP +Pi
OUT: ATP, CoA

Question 8

Succinate goes to

Answer 8

Fumarate

succinate DH

FAD and UQ reduced (2 h’s each)

Question 9

Fumarate onwards?

Answer 9

Maltate formation

h20 in

Fumerase enzyme

Question 10

Formation of oxaloacetate

Answer 10

Maltatate +NAD+

NADH + H+

Maltate dehydrogenase

Question 11

Glyoxylate Pathway?

Answer 11

Isocitrate forms glyoxylate and one molecule of succinate. Glyoxylate combines with acetyle CoA to form Malate.