Citratzyklus Flashcards

1
Q

Start des Citratzykluses:

A

Oxalacetat und Acetyl-CoA -> Citrat

Unter H2O mittels Citrat- Synthase -> CoA-SH wird frei

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2
Q

Schritt 2a

A

Citrat -> Cis-Aconitat

Mittels Aconitase -> H2O wird frei

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3
Q

Schritt 2b

A

Cis-Aconitat -> Isocitrat

Unter H2O mittels Aconitase

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4
Q

Schritt 3a

A

Isocitrat-> Oxalsuccinat

Unter NAD+ mittels Isocitrat-Dehydrogenase -> NADH/H+ entsteht

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5
Q

Schritt 3b

A

Oxalsuccinat-> Alpha-Ketogluterat

Unter H+ mittels Isocitrat-Dehydrogenase-> CO2 wird frei

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6
Q

Schritt 4

A

Alpha- Ketogluterat -> Succinyl-CoA

Unter NAD+ und CoA-SH mittels Alpha- Ketogluterat- Dehydrogenase-> NADH/H+ entsteht, CO2 wird frei

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7
Q

Schritt 5

A

Succinyl-CoA -> Succinat

Unter GDP+Pi mittels Succinyl-CoA-Synthase -> GTP entsteht

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8
Q

Schritt 6

A

Succinat-> Fumerat

Unter FAD mittels Succinyl- Dehydrogenase -> FADH2 entsteht

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9
Q

Schritt 7

A

Fumerat -> L-Malat

Unter H2O mittels Fumerase

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10
Q

Schritt 8

A

L-Malat -> Oxalacetat

Unter NAD+ mittels Malat- Dehydrogenase -> NADH/H+ entsteht

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11
Q

Bilanz des Citratzyklusses

A
2x H2O verbraucht
2x CO2 wird frei
3x NAD+ zu NADH/H+
1x FAD zu FADH2
1x GDP zu GTP

Verbrauch von 1x Acetyl-CoA

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