citrate cycle Flashcards
1
Q
what names
A
- citric acid cycle
- krbs cucle
- tca cycle
2
Q
where is citrc acid cycle located
A
mitochondrion
3
Q
startt component of cac
A
pyruvate from glycolysis
- first it must be transformed to acetyl CoA
- acetyl coa cobines with oxaloacetate from cycle, make citrate
4
Q
what happens to citrate
A
turnes into isocitrate
- isocitrate oxidized by NAD which gives alpha ketoglutarate
5
Q
what happen to alpha ketoglutarate
A
- oxidized by NAD+ to produce succinyl-CoA
- oxidation of succinyl CoA gives succinate and gtp
6
Q
what happen to succinate
A
oxidation by FAD give fumarate
-fumarate converts into malate
7
Q
what happens to malate
A
oxidation by NA produce oxaloacetate
8
Q
what is produced by cac
A
- 6 NADH+H+
- 2 FADH2
- 2ATP
- 4 CO2
nadh+h+ and fadh2 molecules carry electrons to produce ATP
9
Q
what inhibit/activate citrate synthase
A
- NADH+H+ -
- ATP -
- Fatty acyl-CoA -
- AcCoA +
- ADP +
10
Q
what activate/ inhibit isocitrate dehydrogenase
A
- NADH+H+ -
- ATP -
- NAD+ +
- ADP +
11
Q
what activate/ inhibit succinate dehydrogenase
A
- oxaloacetate -
- succinate+
12
Q
energy gain of cac
A
12 ATP per cycle
