Citalopram Flashcards
1
Q
What class of drugs is citalopram part of?
A
SSRIs (antidepressants)
Inhibits the reuptake of serotonin into presynaptic serotonergic nerve terminals
2
Q
What conditions is citalopram licensed to treat?
A
-Depression
-Panic disorder +/- agoraphobia
3
Q
What are the common / most serious side effects of citalopram?
A
-GI: N+V, dyspepsia, abdo pain, diarrhoea
-QT prolongation / torsades de pointes
-Sweating
-Headache
-Insomnia
-Sexual dysfunction
-Increase in anxiety / agitation (in first few weeks)
-Hyponatraemia
-Bleeding disorders
4
Q
What is the recommended dose of citalopram?
A
-20-40mg
-Max dose used to be 60mg but QTc prolongation seen in doses >40mg
