Amitriptyline Flashcards

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1
Q

What class of drugs is amitriptyline?

A

-Tricyclic antidepressant (TCA)
-Block reuptake of serotonin and noradrenaline in presynaptic terminals leading to increased concentrations of these neurotransmitters

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2
Q

What is amitriptyline licensed to treat?

A

-Depression

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3
Q

What are the known side effects of amitriptyline?

A

-Anti-cholinergic: sedation, postural hypotension, tachycardia / arrhythmias, blurred vision, dry mouth, constipation, urinary retention
-Toxic in overdose

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4
Q

What is the recommended dose of amitriptyline?

A

50-200mg

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