Cirrosis/Pancreatitis/Liver Ca/Pancreatic Ca Flashcards
Two causes of pancreatits
Gallstones/Alcohol use
Acute pancreatitis
Release of pancreatic enzymes that “audodigest” the pancreas.
It is reversible
Symptoms of Acute Pancreatitis
LUQ epigastric pain** that is deep and sharp, it intensifies when eating fatty foods ** Abdominal fullness Gas bloating Hiccups and indigestion Fever/Tachy/Hypotension
Diagnosis of Acute Pancreatits
Physical exam: Guarding, rebound tenderness, brusing around umbilicus/flank (indicate bleeding)
Lab tests: Metabolic panel, hemotological, Specific Pancreatic tests (amylase & lipase Most important) elevated BUN (renal function, in sever pancreatitis, indicator of mortality/shock) , Liver enzymes, WBC
Acute pancreatitis management
NPO-prevent release of pancreatic enzymes
IV Fluid-Several L followed by high maintenance fluid to maintain Intravascular volume (lactated ringers/ colloids)
IC level of care if organs involved
Treat cause of pancreatitis
necrotic (IV) vs inflammed (no IV)
Gall bladder vs alcohol
Medications used for patients with Acute pancreatitis
Opiod analgesics Anticholinergics Histamine blockers Pancreatic enzymes Antibiotic therapy
Complication acute pancreatitis
Necrotizing pancreatitis
High rate of complications/mortality
Caused by the pancreatic enzymes that eat through the pancreas and surrounding tissues. Can also cause hemorrhaging from rupture of surround BV
Two types of necrotizing pancreatitis
sterile areas free of bacteria
infected caused by bacteria
Nursing: How would a patient with acute pancreatitis present in hospital (ie vitals, pain level, labs)
Sudden onset of acute unbearable abdominal pain
Elevated heart rate and respiratory rate & low BP
Pain
Elevated serum lipase, amylase, glucose values
Hypocalcemia
Steatorrhea: clay colored stools
MODS: ARDS, PE, Hypoxia, Hypovolemia
What would you assess in a patient with acute pancreatitis
Vital signs O2 status Pain location intensity & duration Abdominal assessment Grey Turners+/o cullens signs Serum lipase & amylase
Serum calcium in acute pancreatitis
Trosseau sign & Chvostek sign
NM irritability bc of the low calcium levels and the the accumulation of fatty acids which cheleate with calcium salts causing deposits in the abd
Trosseau: Hand spasms
Chvostek: :Facial spasms
Why is stool clay colored in acute pancreatits
Obstruction of the bile flow
Nutritional intake acute pancreatits
Loss of appetite because of the pain, or NPO monitor length of NPO and how well they tolerate feedings
Nursing interventions & MEDS acute pancreatits
NPO status
NGT low suction as ordered prevent abd distension
Administer meds: Analgesics, antiemetics, histamine blockers, sedatives/antianxiety meds
What position should acute pancreatits be in bed
Semi fowlers position or fetal position
Encourage coughing and deep breathing
Nurisng teaching acute pancreatitis
Appropiate diet and intake of small freq meals (carbs due to less pancreatic stimulation) and vitamin supplements
abstain from alcohol
abstain from smoking
Disease symptoms, progression, diagnostic procedures and interventions
Patients are progressing well during acute pancreatitis when they have
Stable vitals, weight
Electrolytes w/in normal limits
Decreased pain**
Decreased liver enzymes
Chronic pancreatitis cause
Most common cause is prolonged alcohol use, not reversible (acute is), exocrine and endocrine is altered.
Chronic pancreatitis patho
Inflammation of pancreas
pancreatic enzymes auto-digest pancreas for a long period of time
Scarring occurs resulting in enzyme imbalances
Chronic pancreatitis symptoms
Upper abd pain that can spread to back, worse after eating and drinking (LUQ pain) N/V Weight loss Diarrhea Pale or clay colored stools Steatorrhea (oily stools)
Diagnostic work up of chronic pancreatitis
Abd CT
US
ERCP
Lab analysis (amylase & lipase levels)
Managment of Chronic pancreatitis
Pain mngmnt IV fluid replacement Electrolyte management Nutritional support (significant weight loss) Insulin therapy
Chronic pancreatitis surgical managemnt
Surgical resection
Puestow Procedure
Chronic pancreatitis nursing assessments
Vital signs
Serum BGC levels
Amylase and lipase levels
Serum bilirubin & alkaline phosphatase
Weight, pain, abd
Skin color (jaundice due to obstruction of bile ducts)
Stool
Nursing actions in Chronic pancreatitis
Administer pancreatic enzymes Provide GI prophylaxis (histamine/PPI) Rest and calm environment Implement pain relief measures collaborate with dietician
Nurse teaching Chronic pancreatitis
Avoid alcohol DONT chew pancreatic enzymes bc slow release is needed Limit fat in diet avoid intake of irritating food/bev Referral to support groups
Well managed Chronic pancreatitis
Pain management
Minimize weight loss
Decrease steatorrhea
Risk factors of liver cancer
45-60 yrs Hx of heavy alcohol/smoking Chronic viral hep B or C Enviormental exposure Cirrosis
Liver cancer pathophysiology
Primary hepatocellular carcinoma HCC
Secondary: High blood flow rate/extensive capillary network (cancer components travel via blood to the liver)
Liver cells enlarge and proliferate
Leads to necrosis