Circulatory system Flashcards
Name the two circulating fluids
Blood and Lymph
Another name for tissue fluid
Interstitial fluid
Name two lymphatic organs
Spleen and tonsil
Fluid present in skeletal joints : _________
Fluid present in eye : _____
Synovial fluid
Vitreous humour
pH of Blood
7.3 to 7.45 `
Process by which blood is formed
Haemopoesis
90% of plasma is made of
Water
Plasma from which fibrinogen is removed
Serum
RBCs are also called :
WBCs are also called:
Platelets are also called:
Erythrocyte
Leukocyte
Thrombocyte
Shape of RBCs
Biconcave disc like structure
No. of RBCs/ mm^3 in adult male and female
5 million, 4.5 million
Effective chemical constituent of RBCs
Haemoglobin
Haemoglobin is present in ____ of RBCs
Stroma
Haemoglobin with CO2 and CO
CO2 - Carbaminohaemoglobin
CO - Carboxyhaemoglobin
RBCS in embryo are produced in
Liver and spleen
RBCS in children up to 5 yrs are produced in
bone marrow of all bones
RBCS in adults are produced in
Bone marrow of long bones - rib, breast bone, ilium of hip girdle
avg life of RBCs
120 days
old RBCs are destroyed in
Spleen, liver, bone marrow
three organelles which mature RBC lacks
Nucleus, mitochondria, ER
RBC count lowers by ___% during sleep
5
Abnormal increase in number of RBCs
Polycythaemia
Abnormal decrease in the number of RBCs
Erythropenia
no of WBCs / mm^3 of blood
4000-8000
process by which WBCs can squeeze through walls of capillaries into tissues
Diapedesis
WBCs are mainly produced in
Red bone marrow and lymph nodes
avg life of WBCs
2 weeks
life of neutrophils
few hours
abnormal decrease in number of WBCs
Leukopenia
Cancer of tissue forming WBCs resulting in its increase at the cost of RBCs
Leukaemia
two major categories of WBCs
Granular and non granular
How is the nucleus in granular WBCs
Lobed
How is the nucleus in non-granular WBCs
Single large
multi-lobed WBC
Neutrophil
function of neutrophil
Phagocytosis
neutrophils stain with __ dyes
neutral
bi-lobed WBC
Eosinophil
WBC stained with acidic dyes is ______ and it turns dark red with ____
Eosinophil, eosin
Function of eosinophil
- Phagocytosis
- antitoxins
- associated with allergy
WBC with nucleus large and indistinctly lobed
Basophil
______ WBC stains with basic dyes like ______
Basophil , methylene blue
function of Basophil
Release chemical Histamine for inflammation
What does histamine do
dilates blood vessels
major kind of WBCs
Neutrophils
Smallest of WBCs
Lymphocytes
function of Lymphocytes
Produce antibodies
Largest of WBCs
Monocytes
Shape of nucleus in monocytes
Kidney shaped
at the site of infection , monocytes transform into
Macrophages
function of monocyte
Ingest germs
dead white blood cells together with the tissue cells destroyed by bacteria
Pus
process by which WBCs engulf particle like solid substances, especially bacteria
Phagocytosis
Deliberate introduction of weakened disease germs to stimulate production of specific antibodies
Vaccination
shape of blood platelets
Oval/round
no. of platelets per mm^3 of blood
2 lakh to 4 lakh
Where r platelets produced ?
Megakaryocytes in red bone marrow
Where r platelets destroyed
spleen
life span of platelets
3 to5 days
________ intiate clotting of blood
Thrombokinase
Another name for blood clotting
Coagulation
another name for thrombokinase
thromboplastin , factor X , Stuart factor
What is essential for producing prothrombin
Vitamin K
inactive Prothrombin with the help of thrombokinase and ___ ions coverts into active ____
Calcium, thrombin
Thrombin with the help of ca ions convert _______ which is ___(solubility) in plasma to _____(solubility) ___
Fibrinogen, soluble, insoluble fibrin
fibrin forms ______ combine with RBCs to form a ___
Sticky threads , clot
Clot is also called
Thrombus
Liquid which squeeze out when blood clots
Serum
Is clotting dependent on exposure of blood to air
no
Clotting can even be caused by
movement of blood over rough surface
a condition in which blood fails to clot due to lack of blood clotting proteins
Haemophilia
Who introduced the concept of blood group
Karl Landsteiner
Antigens are present on
Surface of RBCs