Circulatory 2 Flashcards

1
Q

Pulse pressure

A

Difference between systolic and diastolic pressures

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2
Q

Pulse pressure does what in vessels farther from the heart?

A

Widens

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3
Q

Mean arterial pressure continuously ___ throughout the circulatory system

A

Declines

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4
Q

Mean arterial pressure is more dependent on which one: systolic or diastolic pressure?

A

Diastolic pressure; more time is spent in diastole than systole

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5
Q

Where is the greatest decrease in arterial pressure?

A

Across the arterioles

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6
Q

Why does the pulse pressure widen in farther from the heart?

A

Systolic pressure increases and diastolic pressure decreases

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7
Q

Four alterations in pressure profile

A
  1. Widened pulse pressure farther from the heart
  2. High frequency components are dampened
  3. Systolic peak increased and waveform narrowed
  4. Late diastolic hump in the waveform
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8
Q

Possible causes for the diastolic hump

A

Reflection at branch points, vascular tapering, or decrease in arterial compliance

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9
Q

Three layers of the vessel wall

A

Tunica intima, tunica media, tunica adventitia

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10
Q

Tunica intima in the artery wall

A

Subendothelial connective tissue; internal elastic lamina

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11
Q

Tunica media of the artery wall

A

Smooth muscle cells and external elastic lamina

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12
Q

Tunica adventitia of the artery wall

A

Mostly connective tissue with some smooth muscle cells, vasa vasorum, innervation

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13
Q

Tunica intima of the vein wall

A

Subendothelial connective tissue; NO internal elastic lamina

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14
Q

Tunica media in the vein wall

A

Less smooth muscle cells, NO external elastic lamina

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15
Q

Tunica adventitia

A

Well-developed connective tissue with some smooth muscle cells, with vasa vasorum

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16
Q

Main differences between an artery and vein

A

Artery has elastic lamina, more smooth muscle, and less connective tissue

17
Q

Compliance properties of arterial wall components

A

Elastic lamina - highest compliance
Smooth muscle - less compliant than elastin, but more compliant than collagen
Collagen - lowest compliance

18
Q

Continuous capillary

A

Continuous endothelial cells, no fenestrations, tight junctions between cells, continuous basal lamina

19
Q

Where are continuous capillaries found?

A

In muscle and connective tissues

20
Q

Fenestrated capillaries

A

Continuous endothelial cells with fenestrations with or without diaphragms and continuous basal lamina

21
Q

Where are fenestrated capillaries?

A

Found in kidneys and intestines

22
Q

Discontinuous (sinusoidal) capillary

A

Discontinuous endothelial cells separated by wide spaces, discontinuous basal lamina

23
Q

Where are discontinuous capillaries?

A

Liver, bone marrow, spleen

24
Q

Wall thickness/lumen diameter ratio

A

The higher it is, the greater the control of vessel diameter and blood flow

25
Q

Pre-capillary sphincters

A

Highest ratio and greatest control