CINV Flashcards

Question 1

Q

Doxorubicin/Epirubicin + cyclophosphamide

Answer

A

High risk

Question 2

Q

Cisplatin

Answer

A

High risk

Question 3

Q

Doxorubicin > 60 mg/m2

Answer

A

High risk

Question 4

Q

Carboplatin

Answer

A

Moderate risk

Question 5

Q

Irinotecan

Answer

A

Moderate risk

Question 6

Q

Oxaliplatin

Answer

A

Moderate risk

Question 7

Q

Docetaxel/Paclitaxel

Question 8

Q

Etoposide/Topotecan

Question 9

Q

5-FU

Gemcitabine

Question 10

Q

Pemetrexed

Question 11

Q

Bevacizumab
Cetuimab
Ipilumumab
Nivolumab
Pembrolizumab
Pertuzumab
Rituximab
Trastuzumab

Answer

A

Minimal risk

Question 12

Q

Vinca alkaloids

Answer

A

Minimal risk

Question 13

Q

Ceritinib

Crizotonib

Answer

A

Moderate-High risk

Question 14

Q

TKIs

Answer

A

Minimal-low risk

Question 15

Q

Capecitabine

Answer

A

Minimal-low risk

Question 16

Q

Anticipatory

Answer

A

Lorazepam 0.5-2mg Q6H PRN

Question 17

Q

Breakthrough/Refractory

Answer

A

Olanzapine
Lorazepam
Cannabinoids
Haloperidol
Metoclopramide
Scopolamine patch
Prochlorperazine/Promethazine
5-HT3 antagonist
Dexamethasone

Question 18

Q

Minimal risk IV

Answer

A

Breakthrough
+/- Lorazepam 0.5-2 mg Q6H PRN
+/- H2RA or PPI

Question 19

Q

Low risk IV

Answer

A

Dexamethasone 8-12 mg PO/IV daily
+/- Lorazepam
+/- H2RA or PPI

Question 20

Q

Moderate risk IV

Answer

A

Dexamethasone + 5-HT3 antagonist +/- NK-1

Day 1

Dexamethasone 12 mg PO/IV once
Ondansetron 16 mg PO once
+/- Aprepitant 125 mg PO once

Day 2-3
1. Ondansetron 16 mg PO daily
0r
2. Aprepitant 80mg PO daily

Question 21

Q

High risk IV

Answer

A

Dexamehtasone + 5-HT3 + NK-1 antagonist

Day 1

Dexamethasone 12 mg PO/IV once
Ondansetron 16 mg PO once
Aprepitant 125 mg PO once

Day 2-4

Dexamethasone 8 mg PO/IV daily
Aprepitant 80 mg PO daily

Question 22

Q

Low risk oral

Answer

A

Ondansetron 8-16 mg PO daily PRN

Question 23

Q

Moderate-High risk oral

Answer

A

Ondansetron 16-24 mg PO daily