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Pharmacotherapy 7 > CINV > Flashcards

CINV Flashcards

1
Q

Doxorubicin/Epirubicin + cyclophosphamide

A

High risk

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2
Q

Cisplatin

A

High risk

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3
Q

Doxorubicin > 60 mg/m2

A

High risk

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4
Q

Carboplatin

A

Moderate risk

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5
Q

Irinotecan

A

Moderate risk

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6
Q

Oxaliplatin

A

Moderate risk

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7
Q

Docetaxel/Paclitaxel

A

Low risk

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8
Q

Etoposide/Topotecan

A

Low risk

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9
Q

5-FU

Gemcitabine

A

Low risk

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10
Q

Pemetrexed

A

Low risk

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11
Q 
Bevacizumab
Cetuimab
Ipilumumab
Nivolumab
Pembrolizumab
Pertuzumab
Rituximab
Trastuzumab
A

Minimal risk

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12
Q

Vinca alkaloids

A

Minimal risk

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13
Q

Ceritinib

Crizotonib

A

Moderate-High risk

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14
Q

TKIs

A

Minimal-low risk

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15
Q

Capecitabine

A

Minimal-low risk

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16
Q

Anticipatory

A

Lorazepam 0.5-2mg Q6H PRN

17
Q

Breakthrough/Refractory

A 
Olanzapine
Lorazepam
Cannabinoids
Haloperidol
Metoclopramide
Scopolamine patch
Prochlorperazine/Promethazine
5-HT3 antagonist
Dexamethasone
18
Q

Minimal risk IV

A

Breakthrough
+/- Lorazepam 0.5-2 mg Q6H PRN
+/- H2RA or PPI

19
Q

Low risk IV

A

Dexamethasone 8-12 mg PO/IV daily
+/- Lorazepam
+/- H2RA or PPI

20
Q

Moderate risk IV

A

Dexamethasone + 5-HT3 antagonist +/- NK-1

Day 1

  1. Dexamethasone 12 mg PO/IV once
  2. Ondansetron 16 mg PO once
  3. +/- Aprepitant 125 mg PO once

Day 2-3
1. Ondansetron 16 mg PO daily
0r
2. Aprepitant 80mg PO daily

21
Q

High risk IV

A

Dexamehtasone + 5-HT3 + NK-1 antagonist

Day 1

  1. Dexamethasone 12 mg PO/IV once
  2. Ondansetron 16 mg PO once
  3. Aprepitant 125 mg PO once

Day 2-4

  1. Dexamethasone 8 mg PO/IV daily
  2. Aprepitant 80 mg PO daily
22
Q

Low risk oral

A

Ondansetron 8-16 mg PO daily PRN

23
Q

Moderate-High risk oral

A

Ondansetron 16-24 mg PO daily

Pharmacotherapy 7 (7 decks)

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